CRSP (CRISPR Therapeutics AG) OCF Margin %: -10,889.70% (As of Mar. 2026)


CRSP CRISPR Therapeutics AG CRSP
41 GF Score
Price $55.12
GF Value $2.42
Valuation Significantly Overvalued
! 4 Warning Signs
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What is CRISPR Therapeutics AG OCF Margin %?

CRISPR Therapeutics AG CRSP +2.92% 41 OCF Margin % is -10,889.70% as of Mar. 2026. GuruFocus rates CRSP with a GF Score™ of 41/100 and a GF Value™ of $2.42 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 960 Biotechnology companies, CRISPR Therapeutics AG ranks worse than 97.4% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. CRISPR Therapeutics AG's Cash Flow from Operations for the three months ended in Mar. 2026 was $-108.90 Mil. CRISPR Therapeutics AG's Revenue for the three months ended in Mar. 2026 was $1.00 Mil. Therefore, CRISPR Therapeutics AG's OCF Margin % for the quarter that ended in Mar. 2026 was -10,889.70%.

As of today, CRISPR Therapeutics AG's current OCF Yield % is -7.37%.

The historical rank and industry rank for CRISPR Therapeutics AG's OCF Margin % or its related term are showing as below:

CRSP' s OCF Margin % Range Over the Past 10 Years
Min: -113702.06   Med: -407.93   Max: 59.03
Current: -39996.4


During the past 12 years, the highest OCF Margin % of CRISPR Therapeutics AG was 59.03%. The lowest was -113702.06%. And the median was -407.93%.

CRSP's OCF Margin % is ranked worse than
97.4% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs CRSP: -39996.40


CRISPR Therapeutics AG OCF Margin % Related Terms


CRISPR Therapeutics AG OCF Margin % Historical Data

* Premium members only.

The historical data trend for CRISPR Therapeutics AG's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CRISPR Therapeutics AG OCF Margin % Chart

CRISPR Therapeutics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 59.03 -113,702.06 -70.37 -407.93 0.00

CRISPR Therapeutics AG Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -10,889.70

CRSP vs CGON, XENE, DNTH: OCF Margin % Comparison

For the Biotechnology subindustry, CRISPR Therapeutics AG's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CRISPR Therapeutics AG OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, CRISPR Therapeutics AG's OCF Margin % distribution charts can be found below:

* The bar in red indicates where CRISPR Therapeutics AG's OCF Margin % falls into.


CRSP
41GF Score
CRISPR Therapeutics AG CRSP
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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CRISPR Therapeutics AG OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

CRISPR Therapeutics AG's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-345.014/0
= %

CRISPR Therapeutics AG's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-108.897/1
=-10,889.70 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -10,889.70% mean?
CRISPR Therapeutics AG (CRSP) has a OCF Margin % of -10,889.70% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on CRISPR Therapeutics AG and its competitors. According to the industry distribution chart, CRISPR Therapeutics AG ranks #935 out of 960 companies in the Biotechnology industry, placing it in the top 97.4%.
Is CRISPR Therapeutics AG's OCF Margin % too high?
CRISPR Therapeutics AG's current OCF Margin % is -10,889.70%. Based on the distribution chart, CRISPR Therapeutics AG ranks #935 out of 960 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, CRISPR Therapeutics AG has a GF Score™ of 41/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CRISPR Therapeutics AG's OCF Margin % compare to CGON and XENE?
According to the Biotechnology industry distribution chart, CRISPR Therapeutics AG ranks #935 out of 960 companies for OCF Margin %. This places CRISPR Therapeutics AG in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on CRISPR Therapeutics AG and its competitors. CRISPR Therapeutics AG's current OCF Margin % is -10,889.70%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CRISPR Therapeutics AG stock overvalued right now?
Based on GuruFocus' analysis, CRISPR Therapeutics AG (CRSP) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.42, compared to a current price of $55.12 — trading 2177.5% above its estimated fair value. The current OCF Margin % is -10,889.70%. CRISPR Therapeutics AG's overall GF Score™ is 41/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For CRISPR Therapeutics AG (CRSP), the current OCF Margin % is -10,889.70% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CRISPR Therapeutics AG (CRSP) Overvalued in 2026?

Based on GuruFocus' analysis, CRISPR Therapeutics AG stock appears to be overvalued. The current stock price of $55.12 is trading 2177.5% above its estimated GF Value™ of $2.42. GuruFocus considers CRISPR Therapeutics AG to be Significantly Overvalued.

Key valuation signals for CRSP:

  • OCF Margin %: -10,889.70%
  • GF Value™: $2.42 vs. price of $55.12 (2177.5% above fair value)
  • GF Score™: 41/100 with 4 warning signs

No single metric tells the full story. See the CRSP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CRISPR Therapeutics AG Business Description

Address Baarerstrasse 14, Zug, CHE, 6300
Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.
41GF Score

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OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$55.12
Price
$2.42
GF Value