CRSP (CRISPR Therapeutics AG) Total Operating Expense: $445.48 Mil (TTM As of Mar. 2026)


CRSP CRISPR Therapeutics AG CRSP
41 GF Score
Price $62.43
GF Value $2.83
Valuation Significantly Overvalued
! 3 Warning Signs
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What is CRISPR Therapeutics AG Total Operating Expense?

CRISPR Therapeutics AG CRSP +3.91% 41 Total Operating Expense is $445.48 Mil as of Mar. 2026. GuruFocus rates CRSP with a GF Score™ of 41/100 and a GF Value™ of $2.83 (Significantly Overvalued). The stock has 3 warning signs investors should review.

CRISPR Therapeutics AG's Total Operating Expense for the three months ended in Mar. 2026 was $85.30 Mil. CRISPR Therapeutics AG's Total Operating Expense for the trailing twelve months (TTM) ended in Mar. 2026 was $445.48 Mil.

CRISPR Therapeutics AG Total Operating Expense Related Terms

CRISPR Therapeutics AG Total Operating Expense Historical Data

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The historical data trend for CRISPR Therapeutics AG's Total Operating Expense can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CRISPR Therapeutics AG Total Operating Expense Chart

CRISPR Therapeutics AG Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Total Operating Expense
Get a 7-Day Free Trial Premium Member Only Premium Member Only 438.38 563.35 462.29 380.90 451.09

CRISPR Therapeutics AG Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Total Operating Expense Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 90.92 184.17 74.94 101.06 85.30
CRSP
41GF Score
CRISPR Therapeutics AG CRSP
Total Operating Expense is just one metric. See GF Score™, valuation, warning signs, and more.
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CRISPR Therapeutics AG Total Operating Expense Calculation

Total Operating Expense is the primary recurring expense associated with central operations that are incurred in order to generate sales.


Total Operating Expense for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $445.48 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Total Operating Expense of $445.48 Mil mean?
CRISPR Therapeutics AG (CRSP) has a Total Operating Expense of $445.48 Mil as of Mar. 2026. Total operating expense is the primary recurring expense associated with central operations. View historical data on CRISPR Therapeutics AG and its competitors.
Is CRISPR Therapeutics AG's Total Operating Expense too high?
CRISPR Therapeutics AG's current Total Operating Expense is $445.48 Mil. Overall, CRISPR Therapeutics AG has a GF Score™ of 41/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does CRISPR Therapeutics AG's Total Operating Expense compare to ORKA and TVTX?
CRISPR Therapeutics AG's Total Operating Expense of $445.48 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Total Operating Expense for a Biotechnology company?
A good Total Operating Expense depends on the Biotechnology industry context. However, Total Operating Expense should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Total Operating Expense mean?
A high Total Operating Expense can signal that a stock is expensive relative to its fundamentals. Total operating expense is the primary recurring expense associated with central operations. View historical data on CRISPR Therapeutics AG and its competitors. CRISPR Therapeutics AG's current Total Operating Expense is $445.48 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CRISPR Therapeutics AG stock overvalued right now?
Based on GuruFocus' analysis, CRISPR Therapeutics AG (CRSP) is currently considered Significantly Overvalued. The stock's GF Value™ is $2.83, compared to a current price of $62.43 — trading 2106% above its estimated fair value. The current Total Operating Expense is $445.48 Mil. CRISPR Therapeutics AG's overall GF Score™ is 41/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Total Operating Expense calculated?
Total Operating Expense is calculated from a company's financial statements. For CRISPR Therapeutics AG (CRSP), the current Total Operating Expense is $445.48 Mil as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CRISPR Therapeutics AG (CRSP) Overvalued in 2026?

Based on GuruFocus' analysis, CRISPR Therapeutics AG stock appears to be overvalued. The current stock price of $62.43 is trading 2106% above its estimated GF Value™ of $2.83. GuruFocus considers CRISPR Therapeutics AG to be Significantly Overvalued.

Key valuation signals for CRSP:

  • Total Operating Expense: $445.48 Mil
  • GF Value™: $2.83 vs. price of $62.43 (2106% above fair value)
  • GF Score™: 41/100 with 3 warning signs

No single metric tells the full story. See the CRSP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

CRISPR Therapeutics AG Business Description

Address Baarerstrasse 14, Zug, CHE, 6300
Crispr Therapeutics is a gene editing company focused on the development of Crispr/Cas9-based therapeutics. Crispr/Cas9 stands for clustered regularly interspaced short palindromic repeats (Crispr)/Crispr-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. Crispr's first approved drug is Casgevy, which was developed in collaboration with Vertex Pharmaceuticals and targets sickle-cell disease and transfusion-dependent beta-thalassemia. The company is advancing a variety of gene editing programs in immuno-oncology, cardiovascular, and a stem cell-derived therapy to treat Type 1 diabetes.
41GF Score

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Total Operating Expense is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$62.43
Price
$2.83
GF Value