GYRE (Gyre Therapeutics) OCF Margin %: -57.47% (As of Jun. 2026)

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GYRE Gyre Therapeutics Inc GYRE
43 GF Score
Price $6.64
GF Value $9.16
Valuation Modestly Undervalued
! 3 Warning Signs
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What is Gyre Therapeutics OCF Margin %?

Gyre Therapeutics GYRE -0.75% 43 OCF Margin % is -57.47% as of Jun. 2026. GuruFocus rates GYRE with a GF Score™ of 43/100 and a GF Value™ of $9.16 (Modestly Undervalued). The stock has 3 warning signs investors should review. Among 953 Biotechnology companies, Gyre Therapeutics ranks better than 65.69% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Gyre Therapeutics's Cash Flow from Operations for the three months ended in Jun. 2026 was $-16.7 Mil. Gyre Therapeutics's Revenue for the three months ended in Jun. 2026 was $29.1 Mil. Therefore, Gyre Therapeutics's OCF Margin % for the quarter that ended in Jun. 2026 was -57.47%.

As of today, Gyre Therapeutics's current OCF Yield % is -0.70%.

The historical rank and industry rank for Gyre Therapeutics's OCF Margin % or its related term are showing as below:

GYRE' s OCF Margin % Range Over the Past 10 Years
Min: -3.44   Med: 10.44   Max: 23.17
Current: -4.13


During the past 5 years, the highest OCF Margin % of Gyre Therapeutics was 23.17%. The lowest was -3.44%. And the median was 10.44%.

GYRE's OCF Margin % is ranked better than
65.69% of 953 companies
in the Biotechnology industry
Industry Median: -66.92 vs GYRE: -4.13


Gyre Therapeutics OCF Margin % Related Terms


Gyre Therapeutics OCF Margin % Historical Data

* Premium members only.

The historical data trend for Gyre Therapeutics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Gyre Therapeutics OCF Margin % Chart

Gyre Therapeutics Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
OCF Margin %
23.17 10.44 22.82 -3.44 0.87

Gyre Therapeutics Quarterly Data
Dec21 Mar22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -25.14 46.58 -15.12 14.12 -57.47

GYRE vs OCS, RIGL, SGP: OCF Margin % Comparison

For the Biotechnology subindustry, Gyre Therapeutics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Gyre Therapeutics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Gyre Therapeutics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Gyre Therapeutics's OCF Margin % falls into.


GYRE
43GF Score
Gyre Therapeutics Inc GYRE
OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Gyre Therapeutics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Gyre Therapeutics's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=1.01/116.588
=0.87 %

Gyre Therapeutics's OCF Margin for the quarter that ended in Jun. 2026 is calculated as

OCF Margin=Cash Flow from Operations (Q: Jun. 2026 )/Revenue (Q: Jun. 2026 )
=-16.728/29.105
=-57.47 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -57.47% mean?
Gyre Therapeutics (GYRE) has a OCF Margin % of -57.47% as of Jun. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Gyre Therapeutics and its competitors. According to the industry distribution chart, Gyre Therapeutics ranks #327 out of 953 companies in the Biotechnology industry, placing it in the top 34.3%.
Is Gyre Therapeutics' OCF Margin % too high?
Gyre Therapeutics' current OCF Margin % is -57.47%. Based on the distribution chart, Gyre Therapeutics ranks #327 out of 953 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Gyre Therapeutics has a GF Score™ of 43/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Gyre Therapeutics' OCF Margin % compare to OCS and RIGL?
According to the Biotechnology industry distribution chart, Gyre Therapeutics ranks #327 out of 953 companies for OCF Margin %. This puts Gyre Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Gyre Therapeutics and its competitors. Gyre Therapeutics's current OCF Margin % is -57.47%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Gyre Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Gyre Therapeutics (GYRE) is currently considered Modestly Undervalued. The stock's GF Value™ is $9.16, compared to a current price of $6.64 — trading 27.5% below its estimated fair value. The current OCF Margin % is -57.47%. Gyre Therapeutics' overall GF Score™ is 43/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Gyre Therapeutics (GYRE), the current OCF Margin % is -57.47% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Gyre Therapeutics (GYRE) Overvalued in 2026?

Based on GuruFocus' analysis, Gyre Therapeutics stock appears to be undervalued. The current stock price of $6.64 is trading 27.5% below its estimated GF Value™ of $9.16. GuruFocus considers Gyre Therapeutics to be Modestly Undervalued.

Key valuation signals for GYRE:

  • OCF Margin %: -57.47%
  • GF Value™: $9.16 vs. price of $6.64 (27.5% below fair value)
  • GF Score™: 43/100 with 3 warning signs

No single metric tells the full story. See the GYRE stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Gyre Therapeutics Business Description

Other Exchanges L9S:Germany
Address 12770 High Bluff Drive, Suite 150, San Diego, CA, USA, 92130
Gyre Therapeutics Inc is a commercial-stage biopharmaceutical company focused on the development and commercialization of small-molecule therapies for the treatment of organ fibrosis and inflammatory diseases. The company's commercial-stage products include ETUARY, Avatrombopag, and Nintedanib. In addition, it is focused on the development and commercialization of Hydronidone (F351) for the treatment of Metabolic Dysfunction Associated Steatohepatitis (MASH-associated liver fibrosis (MASH fibrosis). Gyre is also advancing a diverse pipeline of different drug candidates in China, including F573, F528, and F230. The company's reportable segments are Gyre Pharmaceuticals, which derives maximum revenue from the sale of ETUARY and certain generic drugs in the PRC, Gyre, and Other.
43GF Score

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OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$6.64
Price
$9.16
GF Value