ITRMF (Iterum Therapeutics) OCF Margin %: -1,909.49% (As of Sep. 2025)


What is Iterum Therapeutics OCF Margin %?

Iterum Therapeutics ITRMF +18.86% OCF Margin % is -1,909.49% as of Sep. 2025. The stock has 4 warning signs investors should review. Among 960 Biotechnology companies, Iterum Therapeutics ranks worse than 91.04% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. Iterum Therapeutics's Cash Flow from Operations for the three months ended in Sep. 2025 was $-7.45 Mil. Iterum Therapeutics's Revenue for the three months ended in Sep. 2025 was $0.39 Mil. Therefore, Iterum Therapeutics's OCF Margin % for the quarter that ended in Sep. 2025 was -1,909.49%.

As of today, Iterum Therapeutics's current OCF Yield % is -652.64%.

The historical rank and industry rank for Iterum Therapeutics's OCF Margin % or its related term are showing as below:

ITRMF' s OCF Margin % Range Over the Past 10 Years
Min: -221410.81   Med: -8889.76   Max: -6024.41
Current: -5003.59

During the past 9 years, the highest OCF Margin % of Iterum Therapeutics was -6024.41%. The lowest was -221410.81%. And the median was -8889.76%.

ITRMF's OCF Margin % is ranked worse than
91.04% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs ITRMF: -5003.59

Iterum Therapeutics OCF Margin % Related Terms

Iterum Therapeutics OCF Margin % Historical Data

* Premium members only.

The historical data trend for Iterum Therapeutics's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Iterum Therapeutics OCF Margin % Chart

Iterum Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
OCF Margin %
Get a 7-Day Free Trial Premium Member Only 0.00 0.00 0.00 0.00 0.00

Iterum Therapeutics Quarterly Data
Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25
OCF Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -1,909.49

ITRMF vs ENSC, PPCB, REVB: OCF Margin % Comparison

For the Biotechnology subindustry, Iterum Therapeutics's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Iterum Therapeutics OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Iterum Therapeutics's OCF Margin % distribution charts can be found below:

* The bar in red indicates where Iterum Therapeutics's OCF Margin % falls into.


Iterum Therapeutics OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

Iterum Therapeutics's OCF Margin for the fiscal year that ended in Dec. 2024 is calculated as

OCF Margin=Cash Flow from Operations (A: Dec. 2024 )/Revenue (A: Dec. 2024 )
=-26.77/0
= %

Iterum Therapeutics's OCF Margin for the quarter that ended in Sep. 2025 is calculated as

OCF Margin=Cash Flow from Operations (Q: Sep. 2025 )/Revenue (Q: Sep. 2025 )
=-7.447/0.39
=-1,909.49 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Margin % →
What does a OCF Margin % of -1,909.49% mean?
Iterum Therapeutics (ITRMF) has a OCF Margin % of -1,909.49% as of Sep. 2025. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Iterum Therapeutics and its competitors. According to the industry distribution chart, Iterum Therapeutics ranks #874 out of 960 companies in the Biotechnology industry, placing it in the top 91%.
Is Iterum Therapeutics' OCF Margin % too high?
Iterum Therapeutics' current OCF Margin % is -1,909.49%. Based on the distribution chart, Iterum Therapeutics ranks #874 out of 960 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Iterum Therapeutics' OCF Margin % compare to ENSC and PPCB?
According to the Biotechnology industry distribution chart, Iterum Therapeutics ranks #874 out of 960 companies for OCF Margin %. This places Iterum Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Iterum Therapeutics and its competitors. Iterum Therapeutics's current OCF Margin % is -1,909.49%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Iterum Therapeutics stock overvalued right now?
Iterum Therapeutics (ITRMF) has a current OCF Margin % of -1,909.49%. The current OCF Margin % is -1,909.49%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Iterum Therapeutics (ITRMF), the current OCF Margin % is -1,909.49% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Iterum Therapeutics Business Description

Address 3 Dublin Landings, North Wall Quay, Dublin 1, Dublin, IRL, D01 C4E0
Iterum Therapeutics PLC is a pharmaceutical company dedicated to maximizing the commercial potential of Orlynvah, an oral-branded penem available in the United States and potentially the first and only oral and intravenous (IV) branded penem available globally. Its product Orlynvah has the potential to be a treatment for complicated urinary tract infections caused by the designated microorganisms, without the presence of known toxicities of some other antibiotics. The company operates in a single business segment, which is the development and commercialization of treatments for drug-resistant bacterial infections.