Iterum TherapeuticsITRMF +18.86% ROA % is -107.99% as of Sep. 2025. The stock has 4 warning signs investors should review. Among 1,423 Biotechnology companies, Iterum Therapeutics ranks worse than 79.34% on this metric.
ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Iterum Therapeutics's annualizedNet Income for the quarter that ended in Sep. 2025 was $-35.92 Mil.
Iterum Therapeutics's average Total Assets over the quarter that ended in Sep. 2025 was $33.26 Mil. Therefore, Iterum Therapeutics's annualized ROA % for the quarter that ended in Sep. 2025 was -107.99%.
The historical rank and industry rank for Iterum Therapeutics's ROA % or its related term are showing as below:
ITRMF'
s ROA % Range Over the Past 10 Years
Min: -177.67 Med: -82.44 Max: -50.02
Current: -84.25
During the past 9 years, Iterum Therapeutics's highest ROA % was -50.02%. The lowest was -177.67%. And the median was -82.44%.
ITRMF's ROA % is ranked worse than 79.34% of 1423
companies
in the Biotechnology industry
Industry Median: -32.9
vs ITRMF: -84.25
Iterum Therapeutics (OTCPK:ITRMF) ROA % Explanation
ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A banks ROA % is typically well under 2%.
Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:
Note:
The Net Income data used here is four times the quarterly (Sep. 2025) net income data. The Revenue data used here is four times the quarterly (Sep. 2025) revenue data.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Be Aware
Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).
Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.
E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.
Iterum Therapeutics ROA % Related Terms
Iterum Therapeutics ROA % Historical Data
* Premium members only.
The historical data trend for Iterum Therapeutics's ROA % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Iterum Therapeutics's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Iterum Therapeutics ROA % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Iterum Therapeutics's ROA % distribution charts can be found below:
* The bar in red indicates where Iterum Therapeutics's ROA % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data,
the Net Income data used here is four times the quarterly (Sep. 2025) net income data.
ROA % is displayed in the 30-year financial page.
Iterum Therapeutics (ITRMF) has a ROA % of -107.99% as of Sep. 2025. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Iterum Therapeutics and its competitors. According to the industry distribution chart, Iterum Therapeutics ranks #1129 out of 1423 companies in the Biotechnology industry, placing it in the top 79.3%.
Is Iterum Therapeutics' ROA % too high?
Iterum Therapeutics' current ROA % is -107.99%. Based on the distribution chart, Iterum Therapeutics ranks #1129 out of 1423 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Iterum Therapeutics' ROA % compare to ENSC and PPCB?
According to the Biotechnology industry distribution chart, Iterum Therapeutics ranks #1129 out of 1423 companies for ROA %. This places Iterum Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Iterum Therapeutics and its competitors. Iterum Therapeutics's current ROA % is -107.99%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Iterum Therapeutics stock overvalued right now?
Iterum Therapeutics (ITRMF) has a current ROA % of -107.99%. The current ROA % is -107.99%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Iterum Therapeutics (ITRMF), the current ROA % is -107.99% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Iterum Therapeutics PLC is a pharmaceutical company dedicated to maximizing the commercial potential of Orlynvah, an oral-branded penem available in the United States and potentially the first and only oral and intravenous (IV) branded penem available globally. Its product Orlynvah has the potential to be a treatment for complicated urinary tract infections caused by the designated microorganisms, without the presence of known toxicities of some other antibiotics. The company operates in a single business segment, which is the development and commercialization of treatments for drug-resistant bacterial infections.
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