ProQR Therapeutics NV (MEX:PRQRN) OCF Margin %: -548.20% (As of Mar. 2026)

What is ProQR Therapeutics NV OCF Margin %?

ProQR Therapeutics NV MEX:PRQRN 44 OCF Margin % is -548.20% as of Mar. 2026. GuruFocus rates MEX:PRQRN with a GF Score™ of 44/100 and a GF Value™ of MXN40.07. The stock has 5 warning signs investors should review. Among 960 Biotechnology companies, ProQR Therapeutics NV ranks worse than 68.65% on this metric.

OCF Margin % is calculated as Cash Flow from Operations divided by its Revenue. ProQR Therapeutics NV's Cash Flow from Operations for the three months ended in Mar. 2026 was MXN-232.3 Mil. ProQR Therapeutics NV's Revenue for the three months ended in Mar. 2026 was MXN42.4 Mil. Therefore, ProQR Therapeutics NV's OCF Margin % for the quarter that ended in Mar. 2026 was -548.20%.

As of today, ProQR Therapeutics NV's current OCF Yield % is -29.30%.

The historical rank and industry rank for ProQR Therapeutics NV's OCF Margin % or its related term are showing as below:

MEX:PRQRN' s OCF Margin % Range Over the Past 10 Years
Min: -1949.07 Med: -331.9 Max: 330.77
Current: -357.6

During the past 13 years, the highest OCF Margin % of ProQR Therapeutics NV was 330.77%. The lowest was -1949.07%. And the median was -331.90%.

MEX:PRQRN's OCF Margin % is ranked worse than
68.65% of 960 companies
in the Biotechnology industry
Industry Median: -68.59 vs MEX:PRQRN: -357.60

ProQR Therapeutics NV OCF Margin % Related Terms

ProQR Therapeutics NV OCF Margin % Historical Data

* Premium members only.

The historical data trend for ProQR Therapeutics NV's OCF Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ProQR Therapeutics NV OCF Margin % Chart

ProQR Therapeutics NV Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

OCF Margin %

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-1,948.45

-1,906.18

330.80

-192.50

-331.89

ProQR Therapeutics NV Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
OCF Margin %	Get a 7-Day Free Trial															-349.59	-298.69	-424.53	-284.92	-548.20

MEX:PRQRN vs GALT, HRTX, PLYX: OCF Margin % Comparison

For the Biotechnology subindustry, ProQR Therapeutics NV's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

ProQR Therapeutics NV OCF Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ProQR Therapeutics NV's OCF Margin % distribution charts can be found below:

* The bar in red indicates where ProQR Therapeutics NV's OCF Margin % falls into.

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44GF Score

ProQR Therapeutics NV MEX:PRQRN

OCF Margin % is just one metric. See GF Score™, valuation, warning signs, and more.

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ProQR Therapeutics NV OCF Margin % Calculation

OCF Margin % is the ratio of Cash Flow from Operations divided by net sales or Revenue, usually presented in percent.

ProQR Therapeutics NV's OCF Margin for the fiscal year that ended in Dec. 2025 is calculated as

OCF Margin	=	Cash Flow from Operations (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-1113.043	/	335.361
	=	-331.89 %

ProQR Therapeutics NV's OCF Margin for the quarter that ended in Mar. 2026 is calculated as

OCF Margin	=	Cash Flow from Operations (Q: Mar. 2026 )	/	Revenue (Q: Mar. 2026 )
	=	-232.34	/	42.382
	=	-548.20 %

Frequently Asked Questions Learn more about OCF Margin % →

What does a OCF Margin % of -548.20% mean?

ProQR Therapeutics NV (MEX:PRQRN) has a OCF Margin % of -548.20% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on ProQR Therapeutics NV and its competitors. According to the industry distribution chart, ProQR Therapeutics NV ranks #659 out of 960 companies in the Biotechnology industry, placing it in the top 68.6%.

Is ProQR Therapeutics NV's OCF Margin % too high?

ProQR Therapeutics NV's current OCF Margin % is -548.20%. Based on the distribution chart, ProQR Therapeutics NV ranks #659 out of 960 companies in the Biotechnology industry, which is below the industry midpoint. Overall, ProQR Therapeutics NV has a GF Score™ of 44/100, reflecting its overall financial health beyond just this single metric.

How does ProQR Therapeutics NV's OCF Margin % compare to GALT and HRTX?

According to the Biotechnology industry distribution chart, ProQR Therapeutics NV ranks #659 out of 960 companies for OCF Margin %. This places ProQR Therapeutics NV in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good OCF Margin % for a Biotechnology company?

A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high OCF Margin % mean?

A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on ProQR Therapeutics NV and its competitors. ProQR Therapeutics NV's current OCF Margin % is -548.20%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is ProQR Therapeutics NV stock overvalued right now?

ProQR Therapeutics NV (MEX:PRQRN) has a current OCF Margin % of -548.20%. The stock's GF Value™ is MXN40.07, compared to a current price of MXN36.00 — trading 10.2% below its estimated fair value. The current OCF Margin % is -548.20%. ProQR Therapeutics NV's overall GF Score™ is 44/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is OCF Margin % calculated?

OCF Margin % is calculated from a company's financial statements. For ProQR Therapeutics NV (MEX:PRQRN), the current OCF Margin % is -548.20% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is ProQR Therapeutics NV (MEX:PRQRN) Overvalued in 2026?

Based on GuruFocus' analysis, ProQR Therapeutics NV stock appears to be undervalued. The current stock price of MXN36.00 is trading 10.2% below its estimated GF Value™ of MXN40.07.

Key valuation signals for MEX:PRQRN:

OCF Margin %: -548.20%
GF Value™: MXN40.07 vs. price of MXN36.00 (10.2% below fair value)
GF Score™: 44/100 with 5 warning signs

No single metric tells the full story. See the MEX:PRQRN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

ProQR Therapeutics NV Business Description

Industry Healthcare Biotechnology

Comparable Companies GALT HRTX PLYX ORMP SPRO PLX MENS NRXP OKUR MIST VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Other Exchanges PRQR:USA 0PQ:Germany

Address Zernikedreef 9, Leiden, ZH, NLD, 2333 CK

Website https://www.proqr.com

ProQR Therapeutics NV is a biopharmaceutical company. It discovers and develops RNA therapeutics for patients with severe genetic rare diseases such as cystic fibrosis, Leber congenital amaurosis type 10, and dystrophic epidermolysis bullosa. The only reportable segment of the company is the discovery and development of different, RNA-based therapeutics. Geographically, the company operates in United States.

44GF Score

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OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN36.00

Price

MXN40.07

GF Value

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