OPKO HealthOPK +2.41%55 OCF Margin % is -15.55% as of Mar. 2026. GuruFocus rates OPK with a GF Score™ of 55/100 and a GF Value™ of $1.06 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 204 Medical Diagnostics & Research companies, OPKO Health ranks worse than 74.51% on this metric.
The historical rank and industry rank for OPKO Health's OCF Margin % or its related term are showing as below:
OPK'
s OCF Margin % Range Over the Past 10 Years
Min: -29.42 Med: -9.51 Max: 2.87
Current: -28.1
During the past 13 years, the highest OCF Margin % of OPKO Health was 2.87%. The lowest was -29.42%. And the median was -9.51%.
OPK's OCF Margin % is ranked worse than 74.51% of 204
companies
in the Medical Diagnostics & Research industry
Industry Median: 4.755
vs OPK: -28.10
OPKO Health OCF Margin % Related Terms
OPKO Health OCF Margin % Historical Data
* Premium members only.
The historical data trend for OPKO Health's OCF Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, OPKO Health's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
OPKO Health OCF Margin % vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, OPKO Health's OCF Margin % distribution charts can be found below:
* The bar in red indicates where OPKO Health's OCF Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
OPKO Health (OPK) has a OCF Margin % of -15.55% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on OPKO Health and its competitors. According to the industry distribution chart, OPKO Health ranks #152 out of 204 companies in the Medical Diagnostics & Research industry, placing it in the top 74.5%.
Is OPKO Health's OCF Margin % too high?
OPKO Health's current OCF Margin % is -15.55%. Based on the distribution chart, OPKO Health ranks #152 out of 204 companies in the Medical Diagnostics & Research industry, which is below the industry midpoint. Overall, OPKO Health has a GF Score™ of 55/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does OPKO Health's OCF Margin % compare to CDNA and PSNL?
According to the Medical Diagnostics & Research industry distribution chart, OPKO Health ranks #152 out of 204 companies for OCF Margin %. This places OPKO Health in the lower half of its industry. The industry median OCF Margin % is 4.76. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Medical Diagnostics & Research company?
The median OCF Margin % among Medical Diagnostics & Research companies is 4.76, based on 204 companies in the industry. Companies in the top quartile (top 25%) have a OCF Margin % significantly above this median, while those in the bottom quartile fall well below. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on OPKO Health and its competitors. For the Medical Diagnostics & Research industry, the median OCF Margin % is 4.76 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. OPKO Health's current OCF Margin % is -15.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is OPKO Health stock overvalued right now?
Based on GuruFocus' analysis, OPKO Health (OPK) is currently considered Significantly Overvalued. The stock's GF Value™ is $1.06, compared to a current price of $1.50 — trading 41.5% above its estimated fair value. The current OCF Margin % is -15.55%. OPKO Health's overall GF Score™ is 55/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For OPKO Health (OPK), the current OCF Margin % is -15.55% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is OPKO Health (OPK) Overvalued in 2026?
Based on GuruFocus' analysis, OPKO Health stock appears to be overvalued.
The current stock price of $1.50 is trading 41.5% above its estimated GF Value™ of $1.06.
GuruFocus considers OPKO Health to be Significantly Overvalued.
Key valuation signals for OPK:
OCF Margin %: -15.55%
GF Value™: $1.06 vs. price of $1.50 (41.5% above fair value)
No single metric tells the full story. See the OPK stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
OPKO Health Inc is a diversified biotechnology company that operates pharmaceutical and diagnostic development programs. Its segments include pharmaceutical and diagnostics. The Pharmaceutical segment consists of its pharmaceutical operations in Chile, Mexico, Ireland, Israel, Spain, Ecuador, France, the United States, and its pharmaceutical research and development operations. The Diagnostics segment consists of clinical and genomics laboratory operations through BioReference and point-of-care operations. It generates the majority of its revenue from the Diagnostics segment.
55GF Score
Get the complete analysis for OPK
OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
OPK has been successfully added to your 
