The historical rank and industry rank for Prothena's OCF Margin % or its related term are showing as below:
STU:0PT'
s OCF Margin % Range Over the Past 10 Years
Min: -11018.96 Med: -1082.94 Max: 46.17
Current: -139.07
During the past 13 years, the highest OCF Margin % of Prothena was 46.17%. The lowest was -11018.96%. And the median was -1082.94%.
STU:0PT's OCF Margin % is ranked worse than 57.93% of 958
companies
in the Biotechnology industry
Industry Median: -68.59
vs STU:0PT: -139.07
Prothena OCF Margin % Related Terms
Prothena OCF Margin % Historical Data
* Premium members only.
The historical data trend for Prothena's OCF Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
STU:0PT vs EDIT, ACHV, XOMA: OCF Margin % Comparison
For the Biotechnology subindustry, Prothena's OCF Margin %, along with its competitors' market caps and OCF Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Prothena OCF Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Prothena's OCF Margin % distribution charts can be found below:
* The bar in red indicates where Prothena's OCF Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Prothena (STU:0PT) has a OCF Margin % of 56.53% as of Mar. 2026. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Prothena and its competitors. According to the industry distribution chart, Prothena ranks #555 out of 958 companies in the Biotechnology industry, placing it in the top 57.9%.
Is Prothena's OCF Margin % too high?
Prothena's current OCF Margin % is 56.53%. Based on the distribution chart, Prothena ranks #555 out of 958 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Prothena has a GF Score™ of 74/100, reflecting its overall financial health beyond just this single metric.
How does Prothena's OCF Margin % compare to EDIT and ACHV?
According to the Biotechnology industry distribution chart, Prothena ranks #555 out of 958 companies for OCF Margin %. This places Prothena in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Margin % for a Biotechnology company?
A good OCF Margin % depends on the Biotechnology industry context. However, OCF Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Margin % mean?
A high OCF Margin % can signal that a stock is expensive relative to its fundamentals. OCF Margin is the ratio of Cash Flow from Operations to Total Revenue. View historical data on Prothena and its competitors. Prothena's current OCF Margin % is 56.53%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Prothena stock overvalued right now?
Prothena (STU:0PT) has a current OCF Margin % of 56.53%. The stock's GF Value™ is €12.85, compared to a current price of €8.72 — trading 32.2% below its estimated fair value. The current OCF Margin % is 56.53%. Prothena's overall GF Score™ is 74/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Margin % calculated?
OCF Margin % is calculated from a company's financial statements. For Prothena (STU:0PT), the current OCF Margin % is 56.53% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Prothena (STU:0PT) Overvalued in 2026?
Based on GuruFocus' analysis, Prothena stock appears to be undervalued.
The current stock price of €8.72 is trading 32.2% below its estimated GF Value™ of €12.85.
Key valuation signals for STU:0PT:
OCF Margin %: 56.53%
GF Value™: €12.85 vs. price of €8.72 (32.2% below fair value)
No single metric tells the full story. See the STU:0PT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Prothena Corp PLC is a late-stage clinical biotechnology company that focuses on protein dysregulation and a pipeline of investigational therapeutics with the potential to change the course of devastating neurodegenerative and rare and peripheral amyloid diseases. Prothena is developing and applying its proprietary CYTOPE technology to target a broad spectrum of intracellular disease pathways in the brain and periphery. The company's pipeline includes both wholly-owned and partnered programs like Prasinezumab, Coramitug (PRX004), BMS-986446 (PRX005), PRX019, TDP-43 CYTOPE, and PRX012-TfR, being developed for the potential treatment of Parkinson's disease, ATTR amyloidosis with cardiomyopathy, Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases.
74GF Score
Get the complete analysis for STU:0PT
OCF Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
STU:0PT has been successfully added to your 
