EZZ Life Science Holdings (ASX:EZZ) Operating Margin %: -0.43% (As of Dec. 2025)

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ASX:EZZ EZZ Life Science Holdings Ltd ASX:EZZ
49 GF Score
Price A$0.48
GF Value A$1.45
Valuation Possible Value Trap
! 4 Warning Signs
View Full Analysis

What is EZZ Life Science Holdings Operating Margin %?

EZZ Life Science Holdings ASX:EZZ +3.23% 49 Operating Margin % is -0.43% as of Dec. 2025. GuruFocus rates ASX:EZZ with a GF Score™ of 49/100 and a GF Value™ of A$1.45 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 941 Biotechnology companies, EZZ Life Science Holdings ranks better than 80.02% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. EZZ Life Science Holdings's Operating Income for the six months ended in Dec. 2025 was A$-0.11 Mil. EZZ Life Science Holdings's Revenue for the six months ended in Dec. 2025 was A$24.82 Mil. Therefore, EZZ Life Science Holdings's Operating Margin % for the quarter that ended in Dec. 2025 was -0.43%.

The historical rank and industry rank for EZZ Life Science Holdings's Operating Margin % or its related term are showing as below:

ASX:EZZ' s Operating Margin % Range Over the Past 10 Years
Min: 8.56   Med: 12.42   Max: 14.85
Current: 8.56


ASX:EZZ's Operating Margin % is ranked better than
80.02% of 941 companies
in the Biotechnology industry
Industry Median: -86.77 vs ASX:EZZ: 8.56

EZZ Life Science Holdings's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

EZZ Life Science Holdings's Operating Income for the six months ended in Dec. 2025 was A$-0.11 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was A$5.26 Mil.


EZZ Life Science Holdings  (ASX:EZZ) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


EZZ Life Science Holdings Operating Margin % Related Terms


EZZ Life Science Holdings Operating Margin % Historical Data

* Premium members only.

The historical data trend for EZZ Life Science Holdings's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

EZZ Life Science Holdings Operating Margin % Chart

EZZ Life Science Holdings Annual Data
Trend Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
Operating Margin %
Get a 7-Day Free Trial 11.54 10.93 12.42 14.62 14.85

EZZ Life Science Holdings Semi-Annual Data
Jun20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only 6.88 18.38 15.08 14.66 -0.43

ASX:EZZ vs VRTX, REGN, RVMD: Operating Margin % Comparison

For the Biotechnology subindustry, EZZ Life Science Holdings's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


EZZ Life Science Holdings Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, EZZ Life Science Holdings's Operating Margin % distribution charts can be found below:

* The bar in red indicates where EZZ Life Science Holdings's Operating Margin % falls into.


ASX:EZZ
49GF Score
EZZ Life Science Holdings Ltd ASX:EZZ
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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EZZ Life Science Holdings Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

EZZ Life Science Holdings's Operating Margin % for the fiscal year that ended in Jun. 2025 is calculated as

Operating Margin %=Operating Income (A: Jun. 2025 ) / Revenue (A: Jun. 2025 )
=9.93 / 66.874
=14.85 %

EZZ Life Science Holdings's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-0.107 / 24.816
=-0.43 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -0.43% mean?
EZZ Life Science Holdings (ASX:EZZ) has a Operating Margin % of -0.43% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on EZZ Life Science Holdings and its competitors. Over the past decade, EZZ Life Science Holdings' Operating Margin % has ranged from 8.56 to 14.85. According to the industry distribution chart, EZZ Life Science Holdings ranks #188 out of 941 companies in the Biotechnology industry, placing it in the top 20%.
Is EZZ Life Science Holdings' Operating Margin % too high?
EZZ Life Science Holdings' current Operating Margin % is -0.43%. Over the past 10 years, this metric has ranged from a low of 8.56 to a high of 14.85. Based on the distribution chart, EZZ Life Science Holdings ranks #188 out of 941 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, EZZ Life Science Holdings has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does EZZ Life Science Holdings' Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, EZZ Life Science Holdings ranks #188 out of 941 companies for Operating Margin %. This places EZZ Life Science Holdings in the top 20% of its industry — outperforming the majority of peers. Historically, EZZ Life Science Holdings' own Operating Margin % has ranged from 8.56 to 14.85 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on EZZ Life Science Holdings and its competitors. EZZ Life Science Holdings's current Operating Margin % is -0.43%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is EZZ Life Science Holdings stock overvalued right now?
Based on GuruFocus' analysis, EZZ Life Science Holdings (ASX:EZZ) is currently considered Possible Value Trap. The stock's GF Value™ is A$1.45, compared to a current price of A$0.48 — trading 66.9% below its estimated fair value. The current Operating Margin % is -0.43%. EZZ Life Science Holdings' overall GF Score™ is 49/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For EZZ Life Science Holdings (ASX:EZZ), the current Operating Margin % is -0.43% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is EZZ Life Science Holdings (ASX:EZZ) Overvalued in 2026?

Based on GuruFocus' analysis, EZZ Life Science Holdings stock appears to be undervalued. The current stock price of A$0.48 is trading 66.9% below its estimated GF Value™ of A$1.45. GuruFocus considers EZZ Life Science Holdings to be Possible Value Trap.

Key valuation signals for ASX:EZZ:

  • Operating Margin %: -0.43%
  • GF Value™: A$1.45 vs. price of A$0.48 (66.9% below fair value)
  • GF Score™: 49/100 with 4 warning signs

No single metric tells the full story. See the ASX:EZZ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


EZZ Life Science Holdings Business Description

Address 55-59 Parramatta Road, Shop 1, Lidcombe, NSW, AUS, 2141
EZZ Life Science Holdings Ltd is a genomic life science company with a mission to improve quality of life and human health. EZZ has a focus on genomic research and development to address four key human health challenges: genetic longevity, human papillomavirus (HPV), helicobacter pylori, and weight management. The company is engaged in formulation, production, marketing and sale of the EZZ branded health and wellbeing products to retailers and consumers domestically and internationally, and wholesale distribution of the EAORON branded skin care products to retailers in Australia and New Zealand.
49GF Score

Get the complete analysis for ASX:EZZ

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

A$0.48
Price
A$1.45
GF Value