CASBF (CanSino Biologics) Operating Margin %: 0.36% (As of Dec. 2025)

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CASBF CanSino Biologics Inc CASBF
69 GF Score
Price $2.60
GF Value $8.72
Valuation Significantly Undervalued
! 3 Warning Signs
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What is CanSino Biologics Operating Margin %?

CanSino Biologics CASBF 69 Operating Margin % is 0.36% as of Dec. 2025. GuruFocus rates CASBF with a GF Score™ of 69/100 and a GF Value™ of $8.72 (Significantly Undervalued). The stock has 3 warning signs investors should review. Among 961 Drug Manufacturers companies, CanSino Biologics ranks worse than 57.44% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. CanSino Biologics's Operating Income for the three months ended in Dec. 2025 was $0.19 Mil. CanSino Biologics's Revenue for the three months ended in Dec. 2025 was $52.08 Mil. Therefore, CanSino Biologics's Operating Margin % for the quarter that ended in Dec. 2025 was 0.36%.

The historical rank and industry rank for CanSino Biologics's Operating Margin % or its related term are showing as below:

CASBF' s Operating Margin % Range Over the Past 10 Years
Min: -13357.39   Med: -140.5   Max: 41.88
Current: 5.17


CASBF's Operating Margin % is ranked worse than
57.44% of 961 companies
in the Drug Manufacturers industry
Industry Median: 7.57 vs CASBF: 5.17

CanSino Biologics's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

CanSino Biologics's Operating Income for the three months ended in Dec. 2025 was $0.19 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was $5.00 Mil.


CanSino Biologics  (OTCPK:CASBF) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


CanSino Biologics Operating Margin % Related Terms


CanSino Biologics Operating Margin % Historical Data

* Premium members only.

The historical data trend for CanSino Biologics's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

CanSino Biologics Operating Margin % Chart

CanSino Biologics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 41.88 -140.50 -602.27 -41.41 2.57

CanSino Biologics Quarterly Data
Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Dec24 Jun25 Sep25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -35.92 0.00 0.00 10.77 0.36

CASBF vs ZTS, UTHR: Operating Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, CanSino Biologics's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


CanSino Biologics Operating Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, CanSino Biologics's Operating Margin % distribution charts can be found below:

* The bar in red indicates where CanSino Biologics's Operating Margin % falls into.


CASBF
69GF Score
CanSino Biologics Inc CASBF
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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CanSino Biologics Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

CanSino Biologics's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=3.864 / 150.414
=2.57 %

CanSino Biologics's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=0.185 / 52.082
=0.36 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.36% mean?
CanSino Biologics (CASBF) has a Operating Margin % of 0.36% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on CanSino Biologics and its competitors. According to the industry distribution chart, CanSino Biologics ranks #552 out of 961 companies in the Drug Manufacturers industry, placing it in the top 57.4%.
Is CanSino Biologics' Operating Margin % too high?
CanSino Biologics' current Operating Margin % is 0.36%. The Drug Manufacturers industry median Operating Margin % is 7.57. CanSino Biologics' value of 0.36% is 95.2% below this industry median. Based on the distribution chart, CanSino Biologics ranks #552 out of 961 companies in the Drug Manufacturers industry, which is below the industry midpoint. Overall, CanSino Biologics has a GF Score™ of 69/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does CanSino Biologics' Operating Margin % compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, CanSino Biologics ranks #552 out of 961 companies for Operating Margin %. This places CanSino Biologics in the lower half of its industry. The industry median Operating Margin % is 7.57. CanSino Biologics' value of 0.36% is 95.2% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.57, based on 961 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. CanSino Biologics's current Operating Margin % of 0.36% is 95.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on CanSino Biologics and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.57 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. CanSino Biologics's current Operating Margin % is 0.36%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is CanSino Biologics stock overvalued right now?
Based on GuruFocus' analysis, CanSino Biologics (CASBF) is currently considered Significantly Undervalued. The stock's GF Value™ is $8.72, compared to a current price of $2.60 — trading 70.2% below its estimated fair value. The current Operating Margin % is 0.36% and 95.2% below the Drug Manufacturers industry median of 7.57. CanSino Biologics' overall GF Score™ is 69/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For CanSino Biologics (CASBF), the current Operating Margin % is 0.36% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is CanSino Biologics (CASBF) Overvalued in 2026?

Based on GuruFocus' analysis, CanSino Biologics stock appears to be undervalued. The current stock price of $2.60 is trading 70.2% below its estimated GF Value™ of $8.72. GuruFocus considers CanSino Biologics to be Significantly Undervalued.

Key valuation signals for CASBF:

  • Operating Margin %: 0.36%
  • GF Value™: $8.72 vs. price of $2.60 (70.2% below fair value)
  • GF Score™: 69/100 with 3 warning signs
  • Industry Position: 95.2% below the Drug Manufacturers median (#552 of 961)

No single metric tells the full story. See the CASBF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


CanSino Biologics Business Description

Address 185 South Avenue, 401-420, 4th Floor, Biomedical Park, TEDA West District, Tianjin, CHN
CanSino Biologics Inc is engaged in the research and development, manufacturing, and commercialization of vaccine products for human use. The company has a broad portfolio of vaccines and vaccine candidates for several disease areas. Its commercial-stage products are Menhycia and Menphecia, iPneucia, Convidecia and Convidecia Air, and XBB.1.5 Variant, and Ad5-EBOV. The company's clinical-stage products include Tetanus Vaccine, DTcP Infant, Tdcp Adolescent and Adult, Recombinant Poliomyelitis Vaccine, PBPV, and Recombinant Zoster Vaccine, among others. Additionally, it has various vaccine candidates in pre-clinical programs, targeting diseases such as influenza, meningitis, pneumonia, and others. Geographically, the company generates maximum revenue from the People's Republic of China.
69GF Score

Get the complete analysis for CASBF

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.60
Price
$8.72
GF Value