CELZ (Creative Medical Technology Holdings) Operating Margin %: 0.00% (As of Mar. 2026)


CELZ Creative Medical Technology Holdings Inc CELZ
36 GF Score
Price $2.01
GF Value $0.32
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Creative Medical Technology Holdings Operating Margin %?

Creative Medical Technology Holdings CELZ +0.50% 36 Operating Margin % is 0.00% as of Mar. 2026. GuruFocus rates CELZ with a GF Score™ of 36/100 and a GF Value™ of $0.32 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 945 Biotechnology companies, Creative Medical Technology Holdings ranks worse than 98.73% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Creative Medical Technology Holdings's Operating Income for the three months ended in Mar. 2026 was $-1.46 Mil. Creative Medical Technology Holdings's Revenue for the three months ended in Mar. 2026 was $0.00 Mil. Therefore, Creative Medical Technology Holdings's Operating Margin % for the quarter that ended in Mar. 2026 was 0.00%.

Warning Sign:

Creative Medical Technology Holdings Inc operating margin has been in a 5-year decline. The average rate of decline per year is -170.7%.

The historical rank and industry rank for Creative Medical Technology Holdings's Operating Margin % or its related term are showing as below:

CELZ' s Operating Margin % Range Over the Past 10 Years
Min: -198066.67   Med: -11510.11   Max: -675.76
Current: -198066.67


CELZ's Operating Margin % is ranked worse than
98.73% of 945 companies
in the Biotechnology industry
Industry Median: -86.89 vs CELZ: -198066.67

Creative Medical Technology Holdings's 5-Year Average Operating Margin % Growth Rate was -170.70% per year.

Creative Medical Technology Holdings's Operating Income for the three months ended in Mar. 2026 was $-1.46 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-5.94 Mil.


Creative Medical Technology Holdings  (NAS:CELZ) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Creative Medical Technology Holdings Operating Margin % Related Terms


Creative Medical Technology Holdings Operating Margin % Historical Data

* Premium members only.

The historical data trend for Creative Medical Technology Holdings's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Creative Medical Technology Holdings Operating Margin % Chart

Creative Medical Technology Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -3,552.27 -11,510.11 -62,444.44 -52,218.18 -102,383.33

Creative Medical Technology Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -55,333.33 0.00 0.00 -64,866.67 0.00

CELZ vs APM, BCLI, GNPX: Operating Margin % Comparison

For the Biotechnology subindustry, Creative Medical Technology Holdings's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Creative Medical Technology Holdings Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Creative Medical Technology Holdings's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Creative Medical Technology Holdings's Operating Margin % falls into.


CELZ
36GF Score
Creative Medical Technology Holdings Inc CELZ
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Creative Medical Technology Holdings Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Creative Medical Technology Holdings's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-6.143 / 0.006
=-102,383.33 %

Creative Medical Technology Holdings's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-1.459 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.00% mean?
Creative Medical Technology Holdings (CELZ) has a Operating Margin % of 0.00% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Creative Medical Technology Holdings and its competitors. According to the industry distribution chart, Creative Medical Technology Holdings ranks #933 out of 945 companies in the Biotechnology industry, placing it in the top 98.7%.
Is Creative Medical Technology Holdings' Operating Margin % too high?
Creative Medical Technology Holdings' current Operating Margin % is 0.00%. Based on the distribution chart, Creative Medical Technology Holdings ranks #933 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Creative Medical Technology Holdings has a GF Score™ of 36/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Creative Medical Technology Holdings' Operating Margin % compare to APM and BCLI?
According to the Biotechnology industry distribution chart, Creative Medical Technology Holdings ranks #933 out of 945 companies for Operating Margin %. This places Creative Medical Technology Holdings in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Creative Medical Technology Holdings and its competitors. Creative Medical Technology Holdings's current Operating Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Creative Medical Technology Holdings stock overvalued right now?
Based on GuruFocus' analysis, Creative Medical Technology Holdings (CELZ) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.32, compared to a current price of $2.01 — trading 528.1% above its estimated fair value. The current Operating Margin % is 0.00%. Creative Medical Technology Holdings' overall GF Score™ is 36/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Creative Medical Technology Holdings (CELZ), the current Operating Margin % is 0.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Creative Medical Technology Holdings (CELZ) Overvalued in 2026?

Based on GuruFocus' analysis, Creative Medical Technology Holdings stock appears to be overvalued. The current stock price of $2.01 is trading 528.1% above its estimated GF Value™ of $0.32. GuruFocus considers Creative Medical Technology Holdings to be Significantly Overvalued.

Key valuation signals for CELZ:

  • Operating Margin %: 0.00%
  • GF Value™: $0.32 vs. price of $2.01 (528.1% above fair value)
  • GF Score™: 36/100 with 4 warning signs

No single metric tells the full story. See the CELZ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Creative Medical Technology Holdings Business Description

Address 211 E Osborn Road, Phoenix, AZ, USA, 85012
Creative Medical Technology Holdings Inc is a commercial-stage biotechnology company focused on the advancement of regenerative therapies in the fields of immunotherapy, endocrinology, urology, neurology, and orthopedics. Its pipeline consists of AlloStem (CELZ-201-DDT); ImmCelz (CELZ-100), a personalized supercharged immune therapy platform; CELZ-201 CREATE-1, an intervention for the treatment of recent onset Type 1 Diabetes; AlloStemSpine for treatment of lower back pain; the Alova program to treat infertility as a result of premature ovarian failure; and other regenerative treatment programs and technologies like OvaStem, CaverStem, FemCelz, StemSpine, and others for the treatment of various indications related to sexual health, spine disc disease, kidney failure, liver failure, etc.
36GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.01
Price
$0.32
GF Value