CELZ (Creative Medical Technology Holdings) ROE % Adjusted to Book Value: -66.00% (As of Mar. 2026)


CELZ Creative Medical Technology Holdings Inc CELZ
34 GF Score
Price $0.81
GF Value $0.32
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Creative Medical Technology Holdings ROE % Adjusted to Book Value?

Creative Medical Technology Holdings CELZ -32.48% 34 ROE % Adjusted to Book Value is -66.00% as of Mar. 2026. GuruFocus rates CELZ with a GF Score™ of 34/100 and a GF Value™ of $0.32 (Significantly Overvalued). The stock has 4 warning signs investors should review.

Creative Medical Technology Holdings's ROE % for the quarter that ended in Mar. 2026 was -82.50%. Creative Medical Technology Holdings's PB Ratio for the quarter that ended in Mar. 2026 was 1.25. Creative Medical Technology Holdings's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -66.00%.


Creative Medical Technology Holdings ROE % Adjusted to Book Value Related Terms


Creative Medical Technology Holdings ROE % Adjusted to Book Value Historical Data

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The historical data trend for Creative Medical Technology Holdings's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Creative Medical Technology Holdings ROE % Adjusted to Book Value Chart

Creative Medical Technology Holdings Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only Negative Equity -228.76 -66.13 -102.88 -90.14

Creative Medical Technology Holdings Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -131.87 -66.25 -51.69 -120.04 -66.00

CELZ vs FBLG, GLMD, ALZN: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Creative Medical Technology Holdings's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Creative Medical Technology Holdings ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Creative Medical Technology Holdings's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Creative Medical Technology Holdings's ROE % Adjusted to Book Value falls into.


CELZ
34GF Score
Creative Medical Technology Holdings Inc CELZ
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Creative Medical Technology Holdings ROE % Adjusted to Book Value Calculation

Creative Medical Technology Holdings's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-86.53% / 0.96
=-90.14%

Creative Medical Technology Holdings's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-82.50% / 1.25
=-66.00%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -66.00% mean?
Creative Medical Technology Holdings (CELZ) has a ROE % Adjusted to Book Value of -66.00% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Creative Medical Technology Holdings and its competitors.
Is Creative Medical Technology Holdings' ROE % Adjusted to Book Value too high?
Creative Medical Technology Holdings' current ROE % Adjusted to Book Value is -66.00%. Overall, Creative Medical Technology Holdings has a GF Score™ of 34/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Creative Medical Technology Holdings' ROE % Adjusted to Book Value compare to FBLG and GLMD?
Creative Medical Technology Holdings' ROE % Adjusted to Book Value of -66.00% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Creative Medical Technology Holdings and its competitors. Creative Medical Technology Holdings's current ROE % Adjusted to Book Value is -66.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Creative Medical Technology Holdings stock overvalued right now?
Based on GuruFocus' analysis, Creative Medical Technology Holdings (CELZ) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.32, compared to a current price of $0.81 — trading 153.2% above its estimated fair value. The current ROE % Adjusted to Book Value is -66.00%. Creative Medical Technology Holdings' overall GF Score™ is 34/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Creative Medical Technology Holdings (CELZ), the current ROE % Adjusted to Book Value is -66.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Creative Medical Technology Holdings (CELZ) Overvalued in 2026?

Based on GuruFocus' analysis, Creative Medical Technology Holdings stock appears to be overvalued. The current stock price of $0.81 is trading 153.2% above its estimated GF Value™ of $0.32. GuruFocus considers Creative Medical Technology Holdings to be Significantly Overvalued.

Key valuation signals for CELZ:

  • ROE % Adjusted to Book Value: -66.00%
  • GF Value™: $0.32 vs. price of $0.81 (153.2% above fair value)
  • GF Score™: 34/100 with 4 warning signs

No single metric tells the full story. See the CELZ stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Creative Medical Technology Holdings Business Description

Address 211 E Osborn Road, Phoenix, AZ, USA, 85012
Creative Medical Technology Holdings Inc is a commercial-stage biotechnology company focused on the advancement of regenerative therapies in the fields of immunotherapy, endocrinology, urology, neurology, and orthopedics. Its pipeline consists of AlloStem (CELZ-201-DDT); ImmCelz (CELZ-100), a personalized supercharged immune therapy platform; CELZ-201 CREATE-1, an intervention for the treatment of recent onset Type 1 Diabetes; AlloStemSpine for treatment of lower back pain; the Alova program to treat infertility as a result of premature ovarian failure; and other regenerative treatment programs and technologies like OvaStem, CaverStem, FemCelz, StemSpine, and others for the treatment of various indications related to sexual health, spine disc disease, kidney failure, liver failure, etc.
34GF Score

Get the complete analysis for CELZ

ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.81
Price
$0.32
GF Value