Zhaoke Ophthalmology (FRA:9FX) Operating Margin %: -722.90% (As of Dec. 2025)

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FRA:9FX Zhaoke Ophthalmology Ltd FRA:9FX
47 GF Score
Price €0.26
GF Value €0.27
! 5 Warning Signs
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What is Zhaoke Ophthalmology Operating Margin %?

Zhaoke Ophthalmology FRA:9FX +0.78% 47 Operating Margin % is -722.90% as of Dec. 2025. GuruFocus rates FRA:9FX with a GF Score™ of 47/100 and a GF Value™ of €0.27. The stock has 5 warning signs investors should review. Among 945 Biotechnology companies, Zhaoke Ophthalmology ranks worse than 76.93% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Zhaoke Ophthalmology's Operating Income for the six months ended in Dec. 2025 was €-14.18 Mil. Zhaoke Ophthalmology's Revenue for the six months ended in Dec. 2025 was €1.96 Mil. Therefore, Zhaoke Ophthalmology's Operating Margin % for the quarter that ended in Dec. 2025 was -722.90%.

The historical rank and industry rank for Zhaoke Ophthalmology's Operating Margin % or its related term are showing as below:

FRA:9FX' s Operating Margin % Range Over the Past 10 Years
Min: -2409.16   Med: -861.57   Max: -411.94
Current: -860.8


FRA:9FX's Operating Margin % is ranked worse than
76.93% of 945 companies
in the Biotechnology industry
Industry Median: -81.29 vs FRA:9FX: -860.80

Zhaoke Ophthalmology's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Zhaoke Ophthalmology's Operating Income for the six months ended in Dec. 2025 was €-14.18 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was €-33.32 Mil.

Warning Sign:

Zhaoke Ophthalmology Ltd has never been profitable in the past 3 years. It lost money every year.


Zhaoke Ophthalmology  (FRA:9FX) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Zhaoke Ophthalmology Operating Margin % Related Terms


Zhaoke Ophthalmology Operating Margin % Historical Data

* Premium members only.

The historical data trend for Zhaoke Ophthalmology's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zhaoke Ophthalmology Operating Margin % Chart

Zhaoke Ophthalmology Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial 0.00 0.00 -2,409.14 -411.95 -861.54

Zhaoke Ophthalmology Semi-Annual Data
Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -2,564.12 -214.31 -914.93 -1,003.46 -722.90

FRA:9FX vs VRTX, REGN, MRNA: Operating Margin % Comparison

For the Biotechnology subindustry, Zhaoke Ophthalmology's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zhaoke Ophthalmology Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Zhaoke Ophthalmology's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Zhaoke Ophthalmology's Operating Margin % falls into.


FRA:9FX
47GF Score
Zhaoke Ophthalmology Ltd FRA:9FX
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Zhaoke Ophthalmology Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Zhaoke Ophthalmology's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-33.402 / 3.877
=-861.54 %

Zhaoke Ophthalmology's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-14.176 / 1.961
=-722.90 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -722.90% mean?
Zhaoke Ophthalmology (FRA:9FX) has a Operating Margin % of -722.90% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Zhaoke Ophthalmology and its competitors. According to the industry distribution chart, Zhaoke Ophthalmology ranks #727 out of 945 companies in the Biotechnology industry, placing it in the top 76.9%.
Is Zhaoke Ophthalmology's Operating Margin % too high?
Zhaoke Ophthalmology's current Operating Margin % is -722.90%. Based on the distribution chart, Zhaoke Ophthalmology ranks #727 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Zhaoke Ophthalmology has a GF Score™ of 47/100, reflecting its overall financial health beyond just this single metric.
How does Zhaoke Ophthalmology's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Zhaoke Ophthalmology ranks #727 out of 945 companies for Operating Margin %. This places Zhaoke Ophthalmology in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Zhaoke Ophthalmology and its competitors. Zhaoke Ophthalmology's current Operating Margin % is -722.90%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zhaoke Ophthalmology stock overvalued right now?
Zhaoke Ophthalmology (FRA:9FX) has a current Operating Margin % of -722.90%. The stock's GF Value™ is €0.27, compared to a current price of €0.26 — trading 4.4% below its estimated fair value. The current Operating Margin % is -722.90%. Zhaoke Ophthalmology's overall GF Score™ is 47/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Zhaoke Ophthalmology (FRA:9FX), the current Operating Margin % is -722.90% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Zhaoke Ophthalmology (FRA:9FX) Overvalued in 2026?

Based on GuruFocus' analysis, Zhaoke Ophthalmology stock appears to be undervalued. The current stock price of €0.26 is trading 4.4% below its estimated GF Value™ of €0.27.

Key valuation signals for FRA:9FX:

  • Operating Margin %: -722.90%
  • GF Value™: €0.27 vs. price of €0.26 (4.4% below fair value)
  • GF Score™: 47/100 with 5 warning signs

No single metric tells the full story. See the FRA:9FX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Zhaoke Ophthalmology Business Description

Other Exchanges 06622:Hong Kong
Address No. 1 Meide 3rd Road, Pearl River Industrial Park, Nansha District, Guangdong Province, Guangzhou, CHN
Zhaoke Ophthalmology Ltd is an ophthalmic pharmaceutical company dedicated to the research, development, manufacture and commercialization of therapies that address unmet medical needs. The company has three flagship drug assets progressing towards potential market approval: NVK002 for myopia, CsA Ophthalmic Gel for DED and TAB014 for wAMD; and two drug assets in the clinical stage BRIMOCHOL PF for presbyopia and ZKY001 for corneal epithelial defects. Geographically the company operates in Hong Kong, Chinese Mainland, South Korea, and Others, of which it generates maximum revenue from Chinese Mainland.
47GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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