Hyloris Pharmaceuticals (LTS:0AB6) Operating Margin %: -99.93% (As of Dec. 2025)


LTS:0AB6 Hyloris Pharmaceuticals SA LTS:0AB6
63 GF Score
Price €4.64
GF Value €9.49
Valuation Possible Value Trap
! 3 Warning Signs
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What is Hyloris Pharmaceuticals Operating Margin %?

Hyloris Pharmaceuticals LTS:0AB6 63 Operating Margin % is -99.93% as of Dec. 2025. GuruFocus rates LTS:0AB6 with a GF Score™ of 63/100 and a GF Value™ of €9.49 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 945 Biotechnology companies, Hyloris Pharmaceuticals ranks worse than 52.28% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Hyloris Pharmaceuticals's Operating Income for the six months ended in Dec. 2025 was €-4.19 Mil. Hyloris Pharmaceuticals's Revenue for the six months ended in Dec. 2025 was €4.19 Mil. Therefore, Hyloris Pharmaceuticals's Operating Margin % for the quarter that ended in Dec. 2025 was -99.93%.

Good Sign:

Hyloris Pharmaceuticals SA operating margin is expanding. Margin expansion is usually a good sign.

The historical rank and industry rank for Hyloris Pharmaceuticals's Operating Margin % or its related term are showing as below:

LTS:0AB6' s Operating Margin % Range Over the Past 10 Years
Min: -6009.89   Med: -1278.67   Max: -75.3
Current: -106.97


LTS:0AB6's Operating Margin % is ranked worse than
52.28% of 945 companies
in the Biotechnology industry
Industry Median: -86.89 vs LTS:0AB6: -106.97

Hyloris Pharmaceuticals's 5-Year Average Operating Margin % Growth Rate was 46.60% per year.

Hyloris Pharmaceuticals's Operating Income for the six months ended in Dec. 2025 was €-4.19 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was €-7.71 Mil.


Hyloris Pharmaceuticals  (LTS:0AB6) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Hyloris Pharmaceuticals Operating Margin % Related Terms


Hyloris Pharmaceuticals Operating Margin % Historical Data

* Premium members only.

The historical data trend for Hyloris Pharmaceuticals's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Hyloris Pharmaceuticals Operating Margin % Chart

Hyloris Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -334.24 -1,278.67 -759.27 -75.30 -106.97

Hyloris Pharmaceuticals Semi-Annual Data
Dec16 Dec17 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -667.41 -94.65 -56.63 -116.73 -99.93

LTS:0AB6 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Hyloris Pharmaceuticals's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Hyloris Pharmaceuticals Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Hyloris Pharmaceuticals's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Hyloris Pharmaceuticals's Operating Margin % falls into.


LTS:0AB6
63GF Score
Hyloris Pharmaceuticals SA LTS:0AB6
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Hyloris Pharmaceuticals Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Hyloris Pharmaceuticals's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-7.709 / 7.207
=-106.97 %

Hyloris Pharmaceuticals's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-4.186 / 4.189
=-99.93 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -99.93% mean?
Hyloris Pharmaceuticals (LTS:0AB6) has a Operating Margin % of -99.93% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Hyloris Pharmaceuticals and its competitors. According to the industry distribution chart, Hyloris Pharmaceuticals ranks #494 out of 945 companies in the Biotechnology industry, placing it in the top 52.3%.
Is Hyloris Pharmaceuticals' Operating Margin % too high?
Hyloris Pharmaceuticals' current Operating Margin % is -99.93%. Based on the distribution chart, Hyloris Pharmaceuticals ranks #494 out of 945 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Hyloris Pharmaceuticals has a GF Score™ of 63/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Hyloris Pharmaceuticals' Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Hyloris Pharmaceuticals ranks #494 out of 945 companies for Operating Margin %. This places Hyloris Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Hyloris Pharmaceuticals and its competitors. Hyloris Pharmaceuticals's current Operating Margin % is -99.93%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Hyloris Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Hyloris Pharmaceuticals (LTS:0AB6) is currently considered Possible Value Trap. The stock's GF Value™ is €9.49, compared to a current price of €4.64 — trading 51.1% below its estimated fair value. The current Operating Margin % is -99.93%. Hyloris Pharmaceuticals' overall GF Score™ is 63/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Hyloris Pharmaceuticals (LTS:0AB6), the current Operating Margin % is -99.93% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Hyloris Pharmaceuticals (LTS:0AB6) Overvalued in 2026?

Based on GuruFocus' analysis, Hyloris Pharmaceuticals stock appears to be undervalued. The current stock price of €4.64 is trading 51.1% below its estimated GF Value™ of €9.49. GuruFocus considers Hyloris Pharmaceuticals to be Possible Value Trap.

Key valuation signals for LTS:0AB6:

  • Operating Margin %: -99.93%
  • GF Value™: €9.49 vs. price of €4.64 (51.1% below fair value)
  • GF Score™: 63/100 with 3 warning signs

No single metric tells the full story. See the LTS:0AB6 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Hyloris Pharmaceuticals Business Description

Other Exchanges 52U:GermanyHYL:Belgium
Address Boulevard Patience et Beaujonc No. 3/1, Liege, BEL, 4000
Hyloris Pharmaceuticals SA is an early-stage specialty pharmaceutical company focused on adding value to the healthcare system by reformulating pharmaceuticals. The company develops proprietary products it believes offer advantages compared to available alternatives, to address the underserved medical needs of patients, hospitals, physicians, payors, and other stakeholders in the healthcare system. Its portfolio spans areas such as cardiovascular, other reformulations, and established markets (high-barrier generics). It has three early commercial-stage products, Sotalol IV for the treatment of atrial fibrillation, Podofilox Ge, and Maxigesic IV. Its revenue is mainly generated in the United States.
63GF Score

Get the complete analysis for LTS:0AB6

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.64
Price
€9.49
GF Value