RLFTY (MindMaze Therapeutics Holding) Operating Margin %: -1,637.10% (As of Dec. 2025)


RLFTY MindMaze Therapeutics Holding SA RLFTY
11 GF Score
Price $0.42
! 2 Warning Signs
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What is MindMaze Therapeutics Holding Operating Margin %?

MindMaze Therapeutics Holding RLFTY 11 Operating Margin % is -1,637.10% as of Dec. 2025. GuruFocus rates RLFTY with a GF Score™ of 11/100. The stock has 2 warning signs investors should review. Among 941 Biotechnology companies, MindMaze Therapeutics Holding ranks worse than 83.1% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. MindMaze Therapeutics Holding's Operating Income for the six months ended in Dec. 2025 was $-13.20 Mil. MindMaze Therapeutics Holding's Revenue for the six months ended in Dec. 2025 was $0.81 Mil. Therefore, MindMaze Therapeutics Holding's Operating Margin % for the quarter that ended in Dec. 2025 was -1,637.10%.

The historical rank and industry rank for MindMaze Therapeutics Holding's Operating Margin % or its related term are showing as below:

RLFTY' s Operating Margin % Range Over the Past 10 Years
Min: -1637.85   Med: -1637.85   Max: -1637.85
Current: -1637.85


RLFTY's Operating Margin % is ranked worse than
83.1% of 941 companies
in the Biotechnology industry
Industry Median: -86.89 vs RLFTY: -1637.85

MindMaze Therapeutics Holding's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

MindMaze Therapeutics Holding's Operating Income for the six months ended in Dec. 2025 was $-13.20 Mil.


MindMaze Therapeutics Holding  (OTCPK:RLFTY) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


MindMaze Therapeutics Holding Operating Margin % Related Terms


MindMaze Therapeutics Holding Operating Margin % Historical Data

* Premium members only.

The historical data trend for MindMaze Therapeutics Holding's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

MindMaze Therapeutics Holding Operating Margin % Chart

MindMaze Therapeutics Holding Annual Data
Trend Dec24 Dec25
Operating Margin %
0.00 -1,637.10

MindMaze Therapeutics Holding Semi-Annual Data
Dec24 Dec25
Operating Margin % 0.00 -1,637.10

RLFTY vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, MindMaze Therapeutics Holding's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


MindMaze Therapeutics Holding Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, MindMaze Therapeutics Holding's Operating Margin % distribution charts can be found below:

* The bar in red indicates where MindMaze Therapeutics Holding's Operating Margin % falls into.


RLFTY
11GF Score
MindMaze Therapeutics Holding SA RLFTY
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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MindMaze Therapeutics Holding Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

MindMaze Therapeutics Holding's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-13.195 / 0.806
=-1,637.10 %

MindMaze Therapeutics Holding's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-13.195 / 0.806
=-1,637.10 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -1,637.10% mean?
MindMaze Therapeutics Holding (RLFTY) has a Operating Margin % of -1,637.10% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on MindMaze Therapeutics Holding and its competitors. According to the industry distribution chart, MindMaze Therapeutics Holding ranks #782 out of 941 companies in the Biotechnology industry, placing it in the top 83.1%.
Is MindMaze Therapeutics Holding's Operating Margin % too high?
MindMaze Therapeutics Holding's current Operating Margin % is -1,637.10%. Based on the distribution chart, MindMaze Therapeutics Holding ranks #782 out of 941 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, MindMaze Therapeutics Holding has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does MindMaze Therapeutics Holding's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, MindMaze Therapeutics Holding ranks #782 out of 941 companies for Operating Margin %. This places MindMaze Therapeutics Holding in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on MindMaze Therapeutics Holding and its competitors. MindMaze Therapeutics Holding's current Operating Margin % is -1,637.10%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is MindMaze Therapeutics Holding stock overvalued right now?
MindMaze Therapeutics Holding (RLFTY) has a current Operating Margin % of -1,637.10%. The current Operating Margin % is -1,637.10%. MindMaze Therapeutics Holding's overall GF Score™ is 11/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For MindMaze Therapeutics Holding (RLFTY), the current Operating Margin % is -1,637.10% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

MindMaze Therapeutics Holding Business Description

Other Exchanges MMTXz:UKMMTX:Switzerland
Address Avenue de Secheron 15, Geneva, CHE, 1202
MindMaze Therapeutics Holding SA is a Swiss-based, commercial-stage biopharmaceutical and neurotechnology company. The company develops and commercializes digital treatments for neurological diseases and brain disorders. Its technology platform integrates software, sensors, and telehealth, and its solutions are used in clinical and home settings internationally. The company has developed evidence-based, next-generation neurotherapeutics that provide evidence-based motor and cognitive treatments to redefine clinical outcomes in patients with neurological disease and brain disorders. The company also manages Relief's existing portfolio of clinical and commercial biopharmaceutical assets focused on rare dermatological, metabolic, and respiratory diseases.
11GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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