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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Alpha TeknovaTKNO +0.56%63 Operating Margin % is -38.80% as of Mar. 2026. GuruFocus rates TKNO with a GF Score™ of 63/100 and a GF Value™ of $3.55 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 959 Drug Manufacturers companies, Alpha Teknova ranks worse than 87.17% on this metric.
Operating Margin % is calculated as Operating Income divided by its Revenue. Alpha Teknova's Operating Income for the
three
months ended in Mar. 2026 was $-4.30 Mil. Alpha Teknova's Revenue for the
three
months ended in Mar. 2026 was $11.08 Mil. Therefore, Alpha Teknova's Operating Margin % for the quarter that ended in Mar. 2026 was -38.80%.
The historical rank and industry rank for Alpha Teknova's Operating Margin % or its related term are showing as below:
TKNO'
s Operating Margin % Range Over the Past 10 Years
Min: -85.05 Med: -41.9 Max: 14.9
Current: -39.02
TKNO's Operating Margin % is ranked worse than 87.17% of 959
companies
in the Drug Manufacturers industry
Industry Median: 7.59
vs TKNO: -39.02
Alpha Teknova's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.
Alpha Teknova's Operating Income for the
three
months ended in Mar. 2026 was $-4.30 Mil.
Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-16.31 Mil.
Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.
Be Aware
Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).
If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.
For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokias Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).
Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.
Alpha Teknova Operating Margin % Related Terms
Alpha Teknova Operating Margin % Historical Data
* Premium members only.
The historical data trend for Alpha Teknova's Operating Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
TKNO vs AKBA, ORGO, SIGA: Operating Margin % Comparison
For the Drug Manufacturers - Specialty & Generic subindustry, Alpha Teknova's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Alpha Teknova Operating Margin % vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Alpha Teknova's Operating Margin % distribution charts can be found below:
* The bar in red indicates where Alpha Teknova's Operating Margin % falls into.
Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.
Alpha Teknova's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Alpha Teknova (TKNO) has a Operating Margin % of -38.80% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Alpha Teknova and its competitors. According to the industry distribution chart, Alpha Teknova ranks #836 out of 959 companies in the Drug Manufacturers industry, placing it in the top 87.2%.
Is Alpha Teknova's Operating Margin % too high?
Alpha Teknova's current Operating Margin % is -38.80%. Based on the distribution chart, Alpha Teknova ranks #836 out of 959 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Alpha Teknova has a GF Score™ of 63/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Alpha Teknova's Operating Margin % compare to AKBA and ORGO?
According to the Drug Manufacturers industry distribution chart, Alpha Teknova ranks #836 out of 959 companies for Operating Margin %. This places Alpha Teknova in the lower half of its industry. The industry median Operating Margin % is 7.59. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.59, based on 959 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Alpha Teknova and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.59 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Alpha Teknova's current Operating Margin % is -38.80%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alpha Teknova stock overvalued right now?
Based on GuruFocus' analysis, Alpha Teknova (TKNO) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.55, compared to a current price of $5.34 — trading 50.4% above its estimated fair value. The current Operating Margin % is -38.80%. Alpha Teknova's overall GF Score™ is 63/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Alpha Teknova (TKNO), the current Operating Margin % is -38.80% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Alpha Teknova (TKNO) Overvalued in 2026?
Based on GuruFocus' analysis, Alpha Teknova stock appears to be overvalued.
The current stock price of $5.34 is trading 50.4% above its estimated GF Value™ of $3.55.
GuruFocus considers Alpha Teknova to be Significantly Overvalued.
Key valuation signals for TKNO:
Operating Margin %: -38.80%
GF Value™: $3.55 vs. price of $5.34 (50.4% above fair value)
No single metric tells the full story. See the TKNO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Alpha Teknova Inc is a producer of critical reagents for the discovery, development, and commercialization of novel therapies, vaccines, and molecular diagnostics. Its offer two primary product categories: Lab Essentials and Clinical Solutions. It derives key revenue from the United States. The company offers three primary product types: (i) pre-poured media plates for cell growth and cloning; (ii) liquid microbial culture media and supplements for cellular expansion; and (iii) molecular biology reagents for sample manipulation, resuspension, and purification.
63GF Score
Get the complete analysis for TKNO
Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
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