TKNO (Alpha Teknova) ROE %: -27.26% (As of Mar. 2026)

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TKNO Alpha Teknova Inc TKNO
63 GF Score
Price $5.34
GF Value $3.55
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Alpha Teknova ROE %?

Alpha Teknova TKNO +0.56% 63 ROE % is -27.26% as of Mar. 2026. GuruFocus rates TKNO with a GF Score™ of 63/100 and a GF Value™ of $3.55 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 937 Drug Manufacturers companies, Alpha Teknova ranks worse than 85.49% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Alpha Teknova's annualized net income for the quarter that ended in Mar. 2026 was $-18.22 Mil. Alpha Teknova's average Total Stockholders Equity over the quarter that ended in Mar. 2026 was $66.85 Mil. Therefore, Alpha Teknova's annualized ROE % for the quarter that ended in Mar. 2026 was -27.26%.

The historical rank and industry rank for Alpha Teknova's ROE % or its related term are showing as below:

TKNO' s ROE % Range Over the Past 10 Years
Min: -39.05   Med: -22.83   Max: 24.06
Current: -23.78

During the past 7 years, Alpha Teknova's highest ROE % was 24.06%. The lowest was -39.05%. And the median was -22.83%.

TKNO's ROE % is ranked worse than
85.49% of 937 companies
in the Drug Manufacturers industry
Industry Median: 6.06 vs TKNO: -23.78

Alpha Teknova  (NAS:TKNO) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-18.22/66.8495
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-18.22 / 44.308)*(44.308 / 101.1205)*(101.1205 / 66.8495)
=Net Margin %*Asset Turnover*Equity Multiplier
=-41.12 %*0.4382*1.5127
=ROA %*Equity Multiplier
=-18.02 %*1.5127
=-27.26 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Mar. 2026 )
=Net Income/Total Stockholders Equity
=-18.22/66.8495
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-18.22 / -18.032) * (-18.032 / -17.192) * (-17.192 / 44.308) * (44.308 / 101.1205) * (101.1205 / 66.8495)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1.0104 * 1.0489 * -38.8 % * 0.4382 * 1.5127
=-27.26 %

Note: The net income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Alpha Teknova ROE % Related Terms


Alpha Teknova ROE % Historical Data

* Premium members only.

The historical data trend for Alpha Teknova's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Alpha Teknova ROE % Chart

Alpha Teknova Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
Get a 7-Day Free Trial -12.26 -39.05 -38.73 -31.02 -22.83

Alpha Teknova Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.08 -18.47 -23.06 -26.91 -27.26

TKNO vs AKBA, ORGO, SIGA: ROE % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Alpha Teknova's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Alpha Teknova ROE % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Alpha Teknova's ROE % distribution charts can be found below:

* The bar in red indicates where Alpha Teknova's ROE % falls into.


TKNO
63GF Score
Alpha Teknova Inc TKNO
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Alpha Teknova ROE % Calculation

Alpha Teknova's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-17.259/( (82.394+68.775)/ 2 )
=-17.259/75.5845
=-22.83 %

Alpha Teknova's annualized ROE % for the quarter that ended in Mar. 2026 is calculated as

ROE %=Net Income (Q: Mar. 2026 )/( (Total Stockholders Equity (Q: Dec. 2025 )+Total Stockholders Equity (Q: Mar. 2026 ))/ count )
=-18.22/( (68.775+64.924)/ 2 )
=-18.22/66.8495
=-27.26 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -27.26% mean?
Alpha Teknova (TKNO) has a ROE % of -27.26% as of Mar. 2026. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Alpha Teknova and its competitors. According to the industry distribution chart, Alpha Teknova ranks #801 out of 937 companies in the Drug Manufacturers industry, placing it in the top 85.5%.
Is Alpha Teknova's ROE % too high?
Alpha Teknova's current ROE % is -27.26%. Based on the distribution chart, Alpha Teknova ranks #801 out of 937 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Alpha Teknova has a GF Score™ of 63/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Alpha Teknova's ROE % compare to AKBA and ORGO?
According to the Drug Manufacturers industry distribution chart, Alpha Teknova ranks #801 out of 937 companies for ROE %. This places Alpha Teknova in the lower half of its industry. The industry median ROE % is 6.06. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Drug Manufacturers company?
The median ROE % among Drug Manufacturers companies is 6.06, based on 937 companies in the industry. Companies in the top quartile (top 25%) have a ROE % significantly above this median, while those in the bottom quartile fall well below. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Alpha Teknova and its competitors. For the Drug Manufacturers industry, the median ROE % is 6.06 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Alpha Teknova's current ROE % is -27.26%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Alpha Teknova stock overvalued right now?
Based on GuruFocus' analysis, Alpha Teknova (TKNO) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.55, compared to a current price of $5.34 — trading 50.4% above its estimated fair value. The current ROE % is -27.26%. Alpha Teknova's overall GF Score™ is 63/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Alpha Teknova (TKNO), the current ROE % is -27.26% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Alpha Teknova (TKNO) Overvalued in 2026?

Based on GuruFocus' analysis, Alpha Teknova stock appears to be overvalued. The current stock price of $5.34 is trading 50.4% above its estimated GF Value™ of $3.55. GuruFocus considers Alpha Teknova to be Significantly Overvalued.

Key valuation signals for TKNO:

  • ROE %: -27.26%
  • GF Value™: $3.55 vs. price of $5.34 (50.4% above fair value)
  • GF Score™: 63/100 with 3 warning signs

No single metric tells the full story. See the TKNO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Alpha Teknova Business Description

Address 2451 Bert Drive, Hollister, CA, USA, 95023
Alpha Teknova Inc is a producer of critical reagents for the discovery, development, and commercialization of novel therapies, vaccines, and molecular diagnostics. Its offer two primary product categories: Lab Essentials and Clinical Solutions. It derives key revenue from the United States. The company offers three primary product types: (i) pre-poured media plates for cell growth and cloning; (ii) liquid microbial culture media and supplements for cellular expansion; and (iii) molecular biology reagents for sample manipulation, resuspension, and purification.
63GF Score

Get the complete analysis for TKNO

ROE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$5.34
Price
$3.55
GF Value