Xlife Sciences AG (XSWX:XLS) Operating Margin %: 28,007.59% (As of Dec. 2025)


XSWX:XLS Xlife Sciences AG XSWX:XLS
50 GF Score
Price CHF20.90
GF Value CHF7.30
Valuation Significantly Overvalued
! 13 Warning Signs
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What is Xlife Sciences AG Operating Margin %?

Xlife Sciences AG XSWX:XLS -11.06% 50 Operating Margin % is 28,007.59% as of Dec. 2025. GuruFocus rates XSWX:XLS with a GF Score™ of 50/100 and a GF Value™ of CHF7.30 (Significantly Overvalued). The stock has 13 warning signs investors should review. Among 945 Biotechnology companies, Xlife Sciences AG ranks worse than 93.65% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Xlife Sciences AG's Operating Income for the six months ended in Dec. 2025 was CHF-22.13 Mil. Xlife Sciences AG's Revenue for the six months ended in Dec. 2025 was CHF-0.08 Mil. Therefore, Xlife Sciences AG's Operating Margin % for the quarter that ended in Dec. 2025 was 28,007.59%.

Warning Sign:

Xlife Sciences AG operating margin has been in a 5-year decline. The average rate of decline per year is -63.8%.

The historical rank and industry rank for Xlife Sciences AG's Operating Margin % or its related term are showing as below:

XSWX:XLS' s Operating Margin % Range Over the Past 10 Years
Min: -11475.27   Med: -2041.15   Max: -149.13
Current: -11475.27


XSWX:XLS's Operating Margin % is ranked worse than
93.65% of 945 companies
in the Biotechnology industry
Industry Median: -86.89 vs XSWX:XLS: -11475.27

Xlife Sciences AG's 5-Year Average Operating Margin % Growth Rate was -63.80% per year.

Xlife Sciences AG's Operating Income for the six months ended in Dec. 2025 was CHF-22.13 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was CHF-31.56 Mil.

Warning Sign:

Xlife Sciences AG has never been profitable in the past 3 years. It lost money every year.


Xlife Sciences AG  (XSWX:XLS) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Xlife Sciences AG Operating Margin % Related Terms


Xlife Sciences AG Operating Margin % Historical Data

* Premium members only.

The historical data trend for Xlife Sciences AG's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Xlife Sciences AG Operating Margin % Chart

Xlife Sciences AG Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial -649.26 -2,041.15 -2,055.47 -2,316.89 -11,474.91

Xlife Sciences AG Semi-Annual Data
Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1,460.16 -2,662.86 -2,067.22 -2,664.12 28,007.59

XSWX:XLS vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Xlife Sciences AG's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Xlife Sciences AG Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Xlife Sciences AG's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Xlife Sciences AG's Operating Margin % falls into.


XSWX:XLS
50GF Score
Xlife Sciences AG XSWX:XLS
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Xlife Sciences AG Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Xlife Sciences AG's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-31.556 / 0.275
=-11,474.91 %

Xlife Sciences AG's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-22.126 / -0.079
=28,007.59 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 28,007.59% mean?
Xlife Sciences AG (XSWX:XLS) has a Operating Margin % of 28,007.59% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Xlife Sciences AG and its competitors. According to the industry distribution chart, Xlife Sciences AG ranks #885 out of 945 companies in the Biotechnology industry, placing it in the top 93.7%.
Is Xlife Sciences AG's Operating Margin % too high?
Xlife Sciences AG's current Operating Margin % is 28,007.59%. Based on the distribution chart, Xlife Sciences AG ranks #885 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Xlife Sciences AG has a GF Score™ of 50/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Xlife Sciences AG's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Xlife Sciences AG ranks #885 out of 945 companies for Operating Margin %. This places Xlife Sciences AG in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Xlife Sciences AG and its competitors. Xlife Sciences AG's current Operating Margin % is 28,007.59%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Xlife Sciences AG stock overvalued right now?
Based on GuruFocus' analysis, Xlife Sciences AG (XSWX:XLS) is currently considered Significantly Overvalued. The stock's GF Value™ is CHF7.30, compared to a current price of CHF20.90 — trading 186.3% above its estimated fair value. The current Operating Margin % is 28,007.59%. Xlife Sciences AG's overall GF Score™ is 50/100 with 13 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Xlife Sciences AG (XSWX:XLS), the current Operating Margin % is 28,007.59% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Xlife Sciences AG (XSWX:XLS) Overvalued in 2026?

Based on GuruFocus' analysis, Xlife Sciences AG stock appears to be overvalued. The current stock price of CHF20.90 is trading 186.3% above its estimated GF Value™ of CHF7.30. GuruFocus considers Xlife Sciences AG to be Significantly Overvalued.

Key valuation signals for XSWX:XLS:

  • Operating Margin %: 28,007.59%
  • GF Value™: CHF7.30 vs. price of CHF20.90 (186.3% above fair value)
  • GF Score™: 50/100 with 13 warning signs

No single metric tells the full story. See the XSWX:XLS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Xlife Sciences AG Business Description

Other Exchanges XLSz:UKXLS:Germany
Address Talacker 35, Zurich, CHE, 8001
Xlife Sciences AG is a Swiss incubator and accelerator company focused on the value development and commercialization of research projects from universities and other life science research institutions, to provide solutions for high-unmet medical needs. It holds majority or minority interests in project companies that are engaged in areas of the company's reportable segments, which include Technology platforms, Medical Technology, Biotechnology/Therapeutics, and Artificial Intelligence/Digital Medicine.
50GF Score

Get the complete analysis for XSWX:XLS

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

CHF20.90
Price
CHF7.30
GF Value