ZYBT (Zhengye Biotechnology Holding) Operating Margin %: -73.80% (As of Dec. 2025)

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ZYBT Zhengye Biotechnology Holding Ltd ZYBT
20 GF Score
Price $1.91
! 5 Warning Signs
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What is Zhengye Biotechnology Holding Operating Margin %?

Zhengye Biotechnology Holding ZYBT -2.05% 20 Operating Margin % is -73.80% as of Dec. 2025. GuruFocus rates ZYBT with a GF Score™ of 20/100. The stock has 5 warning signs investors should review. Among 957 Drug Manufacturers companies, Zhengye Biotechnology Holding ranks worse than 88.92% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Zhengye Biotechnology Holding's Operating Income for the six months ended in Dec. 2025 was $-5.66 Mil. Zhengye Biotechnology Holding's Revenue for the six months ended in Dec. 2025 was $7.67 Mil. Therefore, Zhengye Biotechnology Holding's Operating Margin % for the quarter that ended in Dec. 2025 was -73.80%.

The historical rank and industry rank for Zhengye Biotechnology Holding's Operating Margin % or its related term are showing as below:

ZYBT' s Operating Margin % Range Over the Past 10 Years
Min: -58.79   Med: 22.51   Max: 25.98
Current: -58.79


ZYBT's Operating Margin % is ranked worse than
88.92% of 957 companies
in the Drug Manufacturers industry
Industry Median: 7.96 vs ZYBT: -58.79

Zhengye Biotechnology Holding's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Zhengye Biotechnology Holding's Operating Income for the six months ended in Dec. 2025 was $-5.66 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was $-9.61 Mil.

Warning Sign:

Zhengye Biotechnology Holding Ltd has recorded a loss in operating income at least once over the past 3 years.


Zhengye Biotechnology Holding  (NAS:ZYBT) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Zhengye Biotechnology Holding Operating Margin % Related Terms


Zhengye Biotechnology Holding Operating Margin % Historical Data

* Premium members only.

The historical data trend for Zhengye Biotechnology Holding's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zhengye Biotechnology Holding Operating Margin % Chart

Zhengye Biotechnology Holding Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
25.98 25.39 22.51 9.22 -58.66

Zhengye Biotechnology Holding Semi-Annual Data
Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only 14.27 15.85 2.32 -45.53 -73.80

ZYBT vs TLPH, CPHI, CPIX: Operating Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Zhengye Biotechnology Holding's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zhengye Biotechnology Holding Operating Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Zhengye Biotechnology Holding's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Zhengye Biotechnology Holding's Operating Margin % falls into.


ZYBT
20GF Score
Zhengye Biotechnology Holding Ltd ZYBT
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Zhengye Biotechnology Holding Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Zhengye Biotechnology Holding's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-9.691 / 16.521
=-58.66 %

Zhengye Biotechnology Holding's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-5.662 / 7.672
=-73.80 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -73.80% mean?
Zhengye Biotechnology Holding (ZYBT) has a Operating Margin % of -73.80% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Zhengye Biotechnology Holding and its competitors. According to the industry distribution chart, Zhengye Biotechnology Holding ranks #851 out of 957 companies in the Drug Manufacturers industry, placing it in the top 88.9%.
Is Zhengye Biotechnology Holding's Operating Margin % too high?
Zhengye Biotechnology Holding's current Operating Margin % is -73.80%. Based on the distribution chart, Zhengye Biotechnology Holding ranks #851 out of 957 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Zhengye Biotechnology Holding has a GF Score™ of 20/100, reflecting its overall financial health beyond just this single metric.
How does Zhengye Biotechnology Holding's Operating Margin % compare to TLPH and CPHI?
According to the Drug Manufacturers industry distribution chart, Zhengye Biotechnology Holding ranks #851 out of 957 companies for Operating Margin %. This places Zhengye Biotechnology Holding in the lower half of its industry. The industry median Operating Margin % is 7.96. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.96, based on 957 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Zhengye Biotechnology Holding and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.96 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Zhengye Biotechnology Holding's current Operating Margin % is -73.80%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zhengye Biotechnology Holding stock overvalued right now?
Zhengye Biotechnology Holding (ZYBT) has a current Operating Margin % of -73.80%. The current Operating Margin % is -73.80%. Zhengye Biotechnology Holding's overall GF Score™ is 20/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Zhengye Biotechnology Holding (ZYBT), the current Operating Margin % is -73.80% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Zhengye Biotechnology Holding Business Description

Address No. 1 Lianmeng Road, Jilin Economic & Technical Development Zone, Jilin Province, Jilin City, CHN
Zhengye Biotechnology Holding Ltd is engaged in research, development, manufacturing, and sales of veterinary vaccines, with an emphasis on vaccines for livestock. It has a diverse range of vaccines, including vaccines for swine, cattle, goats, waterfowl, sheep, poultry, and pets, available in various provincial regions across China and are exported overseas to Vietnam, Pakistan, and Egypt. The company generates maximum revenue from the sale of swine vaccines, followed by poultry and other vaccines.
20GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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