ZYBT (Zhengye Biotechnology Holding) ROE %: -35.44% (As of Dec. 2025)

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ZYBT Zhengye Biotechnology Holding Ltd ZYBT
20 GF Score
Price $1.91
! 5 Warning Signs
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What is Zhengye Biotechnology Holding ROE %?

Zhengye Biotechnology Holding ZYBT -2.05% 20 ROE % is -35.44% as of Dec. 2025. GuruFocus rates ZYBT with a GF Score™ of 20/100. The stock has 5 warning signs investors should review. Among 934 Drug Manufacturers companies, Zhengye Biotechnology Holding ranks worse than 85.55% on this metric.

ROE % is calculated as Net Income divided by its average Total Stockholders Equity over a certain period of time. Zhengye Biotechnology Holding's annualized net income for the quarter that ended in Dec. 2025 was $-13.66 Mil. Zhengye Biotechnology Holding's average Total Stockholders Equity over the quarter that ended in Dec. 2025 was $38.55 Mil. Therefore, Zhengye Biotechnology Holding's annualized ROE % for the quarter that ended in Dec. 2025 was -35.44%.

The historical rank and industry rank for Zhengye Biotechnology Holding's ROE % or its related term are showing as below:

ZYBT' s ROE % Range Over the Past 10 Years
Min: -26.61   Med: 10.91   Max: 15.86
Current: -25.45

During the past 5 years, Zhengye Biotechnology Holding's highest ROE % was 15.86%. The lowest was -26.61%. And the median was 10.91%.

ZYBT's ROE % is ranked worse than
85.55% of 934 companies
in the Drug Manufacturers industry
Industry Median: 6.215 vs ZYBT: -25.45

Zhengye Biotechnology Holding  (NAS:ZYBT) ROE % Explanation

ROE % measures the rate of return on the ownership interest (shareholder's equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' equity (also known as net assets or assets minus liabilities). ROE % shows how well a company uses investment funds to generate earnings growth. ROE %s between 15% and 20% are considered desirable.

The factors that affect a company's ROE % can be illustrated with the three-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-13.664/38.5525
=(Net Income / Revenue )*(Revenue / Total Assets)*(Total Assets / Total Stockholders Equity)
=(-13.664 / 15.344)*(15.344 / 66.125)*(66.125 / 38.5525)
=Net Margin %*Asset Turnover*Equity Multiplier
=-89.05 %*0.232*1.7152
=ROA %*Equity Multiplier
=-20.66 %*1.7152
=-35.44 %

With this breakdown, it is clear that if a company grows its Net Profit Margin, its Asset Turnover, or its Leverage, it can grow its ROE %.

The factors that affect a company's ROE % can also be illustrated with the five-step DuPont Analysis:

ROE %(Q: Dec. 2025 )
=Net Income/Total Stockholders Equity
=-13.664/38.5525
=(Net Income / Pre-Tax Income) * (Pre-Tax Income / Operating Income) * (Operating Income / Revenue) * (Revenue / Total Assets) * (Total Assets / Total Stockholders Equity)
= (-13.664 / -11.638) * (-11.638 / -11.324) * (-11.324 / 15.344) * (15.344 / 66.125) * (66.125 / 38.5525)
= Tax Burden * Interest Burden * Operating Margin % * Asset Turnover * Equity Multiplier
= 1.1741 * 1.0277 * -73.8 % * 0.232 * 1.7152
=-35.44 %

Note: The net income data used here is two times the semi-annual (Dec. 2025) net income data. The Revenue data used here is two times the semi-annual (Dec. 2025) revenue data. The same rule applies to Pre-Tax Income and Operating Income.
* In the five-step DuPont Analysis, Operating Income is only available for non-financial companies. Thus, for Insurance companies, we use EBIT as a substitution of Operating Income. For Banks, both Operating Income and EBIT is unavailable. Thus we combined Interest Burden and Operating Margin % into Pretax Margin %, and the DuPont Analysis is divided into four components instead.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Net Income is used.

Because a company can increase its ROE % by having more financial leverage, it is important to watch the equity multiplier when investing in high ROE % companies. Like ROA %, ROE % is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their ROE %s can be extremely high.


Zhengye Biotechnology Holding ROE % Related Terms


Zhengye Biotechnology Holding ROE % Historical Data

* Premium members only.

The historical data trend for Zhengye Biotechnology Holding's ROE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Zhengye Biotechnology Holding ROE % Chart

Zhengye Biotechnology Holding Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
ROE %
14.57 15.86 10.91 4.03 -26.61

Zhengye Biotechnology Holding Semi-Annual Data
Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Get a 7-Day Free Trial Premium Member Only 8.45 6.45 1.62 -14.97 -35.44

ZYBT vs TLPH, CPHI, CPIX: ROE % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Zhengye Biotechnology Holding's ROE %, along with its competitors' market caps and ROE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Zhengye Biotechnology Holding ROE % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Zhengye Biotechnology Holding's ROE % distribution charts can be found below:

* The bar in red indicates where Zhengye Biotechnology Holding's ROE % falls into.


ZYBT
20GF Score
Zhengye Biotechnology Holding Ltd ZYBT
ROE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Zhengye Biotechnology Holding ROE % Calculation

Zhengye Biotechnology Holding's annualized ROE % for the fiscal year that ended in Dec. 2025 is calculated as

ROE %=Net Income (A: Dec. 2025 )/( (Total Stockholders Equity (A: Dec. 2024 )+Total Stockholders Equity (A: Dec. 2025 ))/ count )
=-9.908/( (39.002+35.474)/ 2 )
=-9.908/37.238
=-26.61 %

Zhengye Biotechnology Holding's annualized ROE % for the quarter that ended in Dec. 2025 is calculated as

ROE %=Net Income (Q: Dec. 2025 )/( (Total Stockholders Equity (Q: Jun. 2025 )+Total Stockholders Equity (Q: Dec. 2025 ))/ count )
=-13.664/( (41.631+35.474)/ 2 )
=-13.664/38.5525
=-35.44 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROE %, the net income of the last fiscal year and the average total shareholder equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is two times the semi-annual (Dec. 2025) net income data. ROE % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROE % →
What does a ROE % of -35.44% mean?
Zhengye Biotechnology Holding (ZYBT) has a ROE % of -35.44% as of Dec. 2025. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Zhengye Biotechnology Holding and its competitors. According to the industry distribution chart, Zhengye Biotechnology Holding ranks #799 out of 934 companies in the Drug Manufacturers industry, placing it in the top 85.5%.
Is Zhengye Biotechnology Holding's ROE % too high?
Zhengye Biotechnology Holding's current ROE % is -35.44%. Based on the distribution chart, Zhengye Biotechnology Holding ranks #799 out of 934 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Zhengye Biotechnology Holding has a GF Score™ of 20/100, reflecting its overall financial health beyond just this single metric.
How does Zhengye Biotechnology Holding's ROE % compare to TLPH and CPHI?
According to the Drug Manufacturers industry distribution chart, Zhengye Biotechnology Holding ranks #799 out of 934 companies for ROE %. This places Zhengye Biotechnology Holding in the lower half of its industry. The industry median ROE % is 6.22. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % for a Drug Manufacturers company?
The median ROE % among Drug Manufacturers companies is 6.22, based on 934 companies in the industry. Companies in the top quartile (top 25%) have a ROE % significantly above this median, while those in the bottom quartile fall well below. However, ROE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % mean?
A high ROE % can signal that a stock is expensive relative to its fundamentals. Return on equity is the ratio of current-period net income to average two-period total equity. View historical data on Zhengye Biotechnology Holding and its competitors. For the Drug Manufacturers industry, the median ROE % is 6.22 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Zhengye Biotechnology Holding's current ROE % is -35.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Zhengye Biotechnology Holding stock overvalued right now?
Zhengye Biotechnology Holding (ZYBT) has a current ROE % of -35.44%. The current ROE % is -35.44%. Zhengye Biotechnology Holding's overall GF Score™ is 20/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % calculated?
ROE % is calculated from a company's financial statements. For Zhengye Biotechnology Holding (ZYBT), the current ROE % is -35.44% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Zhengye Biotechnology Holding Business Description

Address No. 1 Lianmeng Road, Jilin Economic & Technical Development Zone, Jilin Province, Jilin City, CHN
Zhengye Biotechnology Holding Ltd is engaged in research, development, manufacturing, and sales of veterinary vaccines, with an emphasis on vaccines for livestock. It has a diverse range of vaccines, including vaccines for swine, cattle, goats, waterfowl, sheep, poultry, and pets, available in various provincial regions across China and are exported overseas to Vietnam, Pakistan, and Egypt. The company generates maximum revenue from the sale of swine vaccines, followed by poultry and other vaccines.
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