GPCR (Structure Therapeutics) PB Ratio: 2.49 (As of Jul. 23, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

GPCR Structure Therapeutics Inc GPCR
32 GF Score
Price $50.80
View Full Analysis

What is Structure Therapeutics PB Ratio?

Structure Therapeutics GPCR +0.70% 32 PB Ratio is 2.49 as of Jul. 23, 2026. GuruFocus rates GPCR with a GF Score™ of 32/100. Among 1,230 Biotechnology companies, Structure Therapeutics ranks better than 54.47% on this metric.

The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-07-23), Structure Therapeutics's share price is $50.80. Structure Therapeutics's Book Value per Share for the quarter that ended in Mar. 2026 was $20.36. Hence, Structure Therapeutics's PB Ratio of today is 2.49.

The historical rank and industry rank for Structure Therapeutics's PB Ratio or its related term are showing as below:

GPCR' s PB Ratio Range Over the Past 10 Years
Min: 0   Med: 0   Max: 2.58
Current: 2.5

During the past 6 years, Structure Therapeutics's highest PB Ratio was 2.58. The lowest was 0.00. And the median was 0.00.

GPCR's PB Ratio is ranked better than
54.47% of 1230 companies
in the Biotechnology industry
Industry Median: 2.82 vs GPCR: 2.50

During the past 12 months, Structure Therapeutics's average Book Value Per Share Growth Rate was 41.80% per year.

Back to Basics: PB Ratio


Structure Therapeutics  (NAS:GPCR) PB Ratio Explanation

Unlike valuation ratios relative to the earning power such as PE Ratio, PE Ratio without NRI, PS Ratio, Price-to-Operating-Cash-Flow , or Price-to-Free-Cash-Flow, the PB Ratio measures the valuation of the stock relative to the underlying asset of the company.

The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.


Be Aware

Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.


Structure Therapeutics PB Ratio Related Terms


Structure Therapeutics PB Ratio Historical Data

* Premium members only.

The historical data trend for Structure Therapeutics's PB Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Structure Therapeutics PB Ratio Chart

Structure Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
PB Ratio
Get a 7-Day Free Trial 0.00 0.00 4.18 1.80 3.25

Structure Therapeutics Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
PB Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.21 1.55 2.21 3.25 2.37

GPCR vs PBLS, IDYA, ELVN: PB Ratio Comparison

For the Biotechnology subindustry, Structure Therapeutics's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Structure Therapeutics PB Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Structure Therapeutics's PB Ratio distribution charts can be found below:

* The bar in red indicates where Structure Therapeutics's PB Ratio falls into.


GPCR
32GF Score
Structure Therapeutics Inc GPCR
PB Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Structure Therapeutics PB Ratio Calculation

The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.

Structure Therapeutics's PB Ratio for today is calculated as follows:

PB Ratio=Share Price/Book Value per Share (Q: Mar. 2026)
=50.80/20.362
=2.49

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

It can also be calculated from the numbers for the whole company:

A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.

Frequently Asked Questions Learn more about PB Ratio →
What does a PB Ratio of 2.49 mean?
Structure Therapeutics (GPCR) has a PB Ratio of 2.49 as of Jul. 23, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Structure Therapeutics and its competitors. According to the industry distribution chart, Structure Therapeutics ranks #560 out of 1230 companies in the Biotechnology industry, placing it in the top 45.5%.
Is Structure Therapeutics' PB Ratio too high?
Structure Therapeutics' current PB Ratio is 2.49. The Biotechnology industry median PB Ratio is 2.82. Structure Therapeutics' value of 2.49 is 11.7% below this industry median. Based on the distribution chart, Structure Therapeutics ranks #560 out of 1230 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Structure Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Structure Therapeutics' PB Ratio compare to PBLS and IDYA?
According to the Biotechnology industry distribution chart, Structure Therapeutics ranks #560 out of 1230 companies for PB Ratio. This puts Structure Therapeutics in the upper half of its industry. The industry median PB Ratio is 2.82. Structure Therapeutics' value of 2.49 is 11.7% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.82, based on 1,230 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Structure Therapeutics's current PB Ratio of 2.49 is 11.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Structure Therapeutics and its competitors. For the Biotechnology industry, the median PB Ratio is 2.82 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Structure Therapeutics's current PB Ratio is 2.49. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Structure Therapeutics stock overvalued right now?
Structure Therapeutics (GPCR) has a current PB Ratio of 2.49. The current PB Ratio is 2.49 and 11.7% below the Biotechnology industry median of 2.82. Structure Therapeutics' overall GF Score™ is 32/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Structure Therapeutics (GPCR), the current PB Ratio is 2.49 as of Jul. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Structure Therapeutics Business Description

Address 601 Gateway Boulevard, Suite 900, South San Francisco, CA, USA, 94080
Structure Therapeutics Inc is a clinical-stage biopharmaceutical company developing novel oral small-molecule therapeutics to treat a wide range of chronic diseases with unmet medical needs. Its differentiated technology platform leverages both structure-based drug discovery and expertise in computational chemistry to discover and develop small molecule therapeutics against G-protein coupled receptors (GPCRs). The group operates and manages its business as one reportable and operating segment, which is the business of research and development of medicines that target chronic diseases with unmet medical needs.
32GF Score

Get the complete analysis for GPCR

PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$50.80
Price