IlluminaXSWX:ILMN -0.79%76 PB Ratio is 10.39 as of Jun. 27, 2026, which is 11% above its 10-year median of 9.40. GuruFocus rates XSWX:ILMN with a GF Score™ of 76/100 and a GF Value™ of CHF105.33. The stock has 7 warning signs investors should review. Among 196 Medical Diagnostics & Research companies, Illumina ranks worse than 87.76% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-06-27), Illumina's share price is CHF143.95. Illumina's Book Value per Share for the quarter that ended in Mar. 2026 was CHF13.86. Hence, Illumina's PB Ratio of today is 10.39.
Warning Sign:
Illumina Inc stock PB Ratio (=10.03) is close to 1-year high of 10.03.
The historical rank and industry rank for Illumina's PB Ratio or its related term are showing as below:
XSWX:ILMN'
s PB Ratio Range Over the Past 10 Years
Min: 2.47 Med: 9.4 Max: 16.1
Current: 10.03
During the past 13 years, Illumina's highest PB Ratio was 16.10. The lowest was 2.47. And the median was 9.40.
XSWX:ILMN's PB Ratio is ranked worse than 87.76% of 196
companies
in the Medical Diagnostics & Research industry
Industry Median: 2.05
vs XSWX:ILMN: 10.03
During the past 12 months, Illumina's average Book Value Per Share Growth Rate was 18.20% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -24.70% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -19.70% per year.
During the past 10 years, the average Book Value Per Share Growth Rate was 5.10% per year.
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of Illumina was 95.90% per year. The lowest was -39.80% per year. And the median was 10.10% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Illumina PB Ratio Related Terms
Illumina PB Ratio Historical Data
* Premium members only.
The historical data trend for Illumina's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Diagnostics & Research subindustry, Illumina's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Illumina PB Ratio vs Medical Diagnostics & Research Industry
For the Medical Diagnostics & Research industry and Healthcare sector, Illumina's PB Ratio distribution charts can be found below:
* The bar in red indicates where Illumina's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
Illumina's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Illumina (XSWX:ILMN) has a PB Ratio of 10.39 as of Jun. 27, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Illumina and its competitors. This is 11% above median its historical median of 9.40. Over the past decade, Illumina's PB Ratio has ranged from 2.47 to 16.10. According to the industry distribution chart, Illumina ranks #172 out of 196 companies in the Medical Diagnostics & Research industry, placing it in the top 87.8%.
Is Illumina's PB Ratio too high?
Illumina's current PB Ratio of 10.39 is 11% above median its 10-year median of 9.40. Over the past 10 years, this metric has ranged from a low of 2.47 to a high of 16.10. The Medical Diagnostics & Research industry median PB Ratio is 2.05. Illumina's value of 10.39 is 406.8% above this industry median. Based on the distribution chart, Illumina ranks #172 out of 196 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, Illumina has a GF Score™ of 76/100, reflecting its overall financial health beyond just this single metric.
How does Illumina's PB Ratio compare to MTD and DGX?
According to the Medical Diagnostics & Research industry distribution chart, Illumina ranks #172 out of 196 companies for PB Ratio. This places Illumina in the lower half of its industry. The industry median PB Ratio is 2.05. Illumina's value of 10.39 is 406.8% above this benchmark. Historically, Illumina's own PB Ratio has ranged from 2.47 to 16.10 over the past decade. While the company's 10-year median is 9.40 vs. the industry median of 2.05, Illumina has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Medical Diagnostics & Research company?
The median PB Ratio among Medical Diagnostics & Research companies is 2.05, based on 196 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Illumina's current PB Ratio of 10.39 is 406.8% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Illumina and its competitors. For the Medical Diagnostics & Research industry, the median PB Ratio is 2.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Illumina's current PB Ratio is 10.39, which is 11% above median its own 10-year median of 9.40. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Illumina (XSWX:ILMN) has a current PB Ratio of 10.39. The stock's GF Value™ is CHF105.33, compared to a current price of CHF143.95 — trading 36.7% above its estimated fair value. The current PB Ratio is 10.39, which is 11% above median its 10-year median of 9.40 and 406.8% above the Medical Diagnostics & Research industry median of 2.05. Illumina's overall GF Score™ is 76/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Illumina (XSWX:ILMN), the current PB Ratio is 10.39 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Illumina (XSWX:ILMN) Overvalued in 2026?
Based on GuruFocus' analysis, Illumina stock appears to be overvalued.
The current stock price of CHF143.95 is trading 36.7% above its estimated GF Value™ of CHF105.33.
Key valuation signals for XSWX:ILMN:
PB Ratio: 10.39 (11% above median its 10-year median of 9.40)
GF Value™: CHF105.33 vs. price of CHF143.95 (36.7% above fair value)
Industry Position: 406.8% above the Medical Diagnostics & Research median (#172 of 196)
No single metric tells the full story. See the XSWX:ILMN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
76GF Score
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