Rhythm Pharmaceuticals (MEX:RYTM) Pretax Margin %: -91.65% (As of Mar. 2026)


MEX:RYTM Rhythm Pharmaceuticals Inc MEX:RYTM
56 GF Score
Price MXN1,866.76
GF Value MXN1,874.87
! 3 Warning Signs
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What is Rhythm Pharmaceuticals Pretax Margin %?

Rhythm Pharmaceuticals MEX:RYTM 56 Pretax Margin % is -91.65% as of Mar. 2026. GuruFocus rates MEX:RYTM with a GF Score™ of 56/100 and a GF Value™ of MXN1,874.87. The stock has 3 warning signs investors should review. Among 942 Biotechnology companies, Rhythm Pharmaceuticals ranks worse than 50.32% on this metric.

Pre-Tax margin is calculated as Pre-Tax Income divided by its Revenue. Rhythm Pharmaceuticals's Pre-Tax Income for the three months ended in Mar. 2026 was MXN-993 Mil. Rhythm Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was MXN1,084 Mil. Therefore, Rhythm Pharmaceuticals's pretax margin for the quarter that ended in Mar. 2026 was -91.65%.

The historical rank and industry rank for Rhythm Pharmaceuticals's Pretax Margin % or its related term are showing as below:

MEX:RYTM' s Pretax Margin % Range Over the Past 10 Years
Min: -2207.1   Med: -237.79   Max: -92.89
Current: -92.89


MEX:RYTM's Pretax Margin % is ranked worse than
50.32% of 942 companies
in the Biotechnology industry
Industry Median: -90.5 vs MEX:RYTM: -92.89

Rhythm Pharmaceuticals  (MEX:RYTM) Pretax Margin % Explanation

The pretax margin, as know as pretax profit margin, is widely used to measure the operating efficiency of a company before deducting taxes.

The pretax margin is sometimes preferred over the net margin as tax expenditures can make profitability comparisons between companies misleading.

It is a useful tool to compare companies operating in the same sector and less effective when comparing companies from other sectors as each industry generally has different operating expenses and sales patterns.

The long term trend of the pretax margin is a good indicator of the competitiveness and health of the business.


Rhythm Pharmaceuticals Pretax Margin % Related Terms


Rhythm Pharmaceuticals Pretax Margin % Historical Data

* Premium members only.

The historical data trend for Rhythm Pharmaceuticals's Pretax Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Rhythm Pharmaceuticals Pretax Margin % Chart

Rhythm Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Pretax Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2,207.11 -766.22 -237.79 -200.00 -103.31

Rhythm Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Pretax Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -151.11 -95.45 -102.91 -83.03 -91.65

MEX:RYTM vs MIRM, SYRE, PTGX: Pretax Margin % Comparison

For the Biotechnology subindustry, Rhythm Pharmaceuticals's Pretax Margin %, along with its competitors' market caps and Pretax Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Rhythm Pharmaceuticals Pretax Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Rhythm Pharmaceuticals's Pretax Margin % distribution charts can be found below:

* The bar in red indicates where Rhythm Pharmaceuticals's Pretax Margin % falls into.


MEX:RYTM
56GF Score
Rhythm Pharmaceuticals Inc MEX:RYTM
Pretax Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Rhythm Pharmaceuticals Pretax Margin % Calculation

Pretax margin - also known as pretax profit margin is the ratio of Pretax Income divided by net sales or Revenue, usually presented in percent.

Rhythm Pharmaceuticals's Pretax Margin for the fiscal year that ended in Dec. 2025 is calculated as

Pretax Margin=Pre-Tax Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-3529.873/3416.708
=-103.31 %

Rhythm Pharmaceuticals's Pretax Margin for the quarter that ended in Mar. 2026 is calculated as

Pretax Margin=Pre-Tax Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-993.494/1083.982
=-91.65 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Pretax Margin % →
What does a Pretax Margin % of -91.65% mean?
Rhythm Pharmaceuticals (MEX:RYTM) has a Pretax Margin % of -91.65% as of Mar. 2026. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Rhythm Pharmaceuticals and its competitors. According to the industry distribution chart, Rhythm Pharmaceuticals ranks #474 out of 942 companies in the Biotechnology industry, placing it in the top 50.3%.
Is Rhythm Pharmaceuticals' Pretax Margin % too high?
Rhythm Pharmaceuticals' current Pretax Margin % is -91.65%. Based on the distribution chart, Rhythm Pharmaceuticals ranks #474 out of 942 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Rhythm Pharmaceuticals has a GF Score™ of 56/100, reflecting its overall financial health beyond just this single metric.
How does Rhythm Pharmaceuticals' Pretax Margin % compare to MIRM and SYRE?
According to the Biotechnology industry distribution chart, Rhythm Pharmaceuticals ranks #474 out of 942 companies for Pretax Margin %. This places Rhythm Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Pretax Margin % for a Biotechnology company?
A good Pretax Margin % depends on the Biotechnology industry context. However, Pretax Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Pretax Margin % mean?
A high Pretax Margin % can signal that a stock is expensive relative to its fundamentals. Pre-Tax margin is the ratio of total pre-tax income to net sales. View historical data on Rhythm Pharmaceuticals and its competitors. Rhythm Pharmaceuticals's current Pretax Margin % is -91.65%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Rhythm Pharmaceuticals stock overvalued right now?
Rhythm Pharmaceuticals (MEX:RYTM) has a current Pretax Margin % of -91.65%. The stock's GF Value™ is MXN1,874.87, compared to a current price of MXN1,866.76 — trading 0.4% below its estimated fair value. The current Pretax Margin % is -91.65%. Rhythm Pharmaceuticals' overall GF Score™ is 56/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Pretax Margin % calculated?
Pretax Margin % is calculated from a company's financial statements. For Rhythm Pharmaceuticals (MEX:RYTM), the current Pretax Margin % is -91.65% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Rhythm Pharmaceuticals (MEX:RYTM) Overvalued in 2026?

Based on GuruFocus' analysis, Rhythm Pharmaceuticals stock appears to be undervalued. The current stock price of MXN1,866.76 is trading 0.4% below its estimated GF Value™ of MXN1,874.87.

Key valuation signals for MEX:RYTM:

  • Pretax Margin %: -91.65%
  • GF Value™: MXN1,874.87 vs. price of MXN1,866.76 (0.4% below fair value)
  • GF Score™: 56/100 with 3 warning signs

No single metric tells the full story. See the MEX:RYTM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Rhythm Pharmaceuticals Business Description

Other Exchanges RYTM:USA1RV:Germany
Address 222 Berkeley Street, 12th Floor, Boston, MA, USA, 02116
Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
56GF Score

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Pretax Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,866.76
Price
MXN1,874.87
GF Value