Rhythm Pharmaceuticals (MEX:RYTM) Shiller PE Ratio: (As of Aug. 24, 2026)

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MEX:RYTM Rhythm Pharmaceuticals Inc MEX:RYTM
57 GF Score
Price MXN1,866.76
GF Value MXN2,035.63
! 3 Warning Signs
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What is Rhythm Pharmaceuticals Shiller PE Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Rhythm Pharmaceuticals  (MEX:RYTM) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


Rhythm Pharmaceuticals Shiller PE Ratio Related Terms


Rhythm Pharmaceuticals Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for Rhythm Pharmaceuticals's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Rhythm Pharmaceuticals Shiller PE Ratio Chart

Rhythm Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Rhythm Pharmaceuticals Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

MEX:RYTM vs MIRM, COGT, ERAS: Shiller PE Ratio Comparison

For the Biotechnology subindustry, Rhythm Pharmaceuticals's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Rhythm Pharmaceuticals Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Rhythm Pharmaceuticals's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Rhythm Pharmaceuticals's Shiller PE Ratio falls into.


MEX:RYTM
57GF Score
Rhythm Pharmaceuticals Inc MEX:RYTM
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Rhythm Pharmaceuticals Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Rhythm Pharmaceuticals's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, Rhythm Pharmaceuticals's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-12.738/333.9520*333.9520
=-12.738

Current CPI (Jun. 2026) = 333.9520.

Rhythm Pharmaceuticals Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 -8.311 241.428 -11.496
201612 -11.303 241.432 -15.634
201703 -8.470 243.801 -11.602
201706 -5.552 244.955 -7.569
201709 -7.955 246.819 -10.763
201712 -8.052 246.524 -10.908
201803 -10.901 249.554 -14.588
201806 -10.218 251.989 -13.542
201809 -9.727 252.439 -12.868
201812 -14.530 251.233 -19.314
201903 -16.294 254.202 -21.406
201906 -23.819 256.143 -31.055
201909 -20.532 256.759 -26.705
201912 -14.711 256.974 -19.118
202003 -18.289 258.115 -23.663
202006 -16.388 257.797 -21.229
202009 -17.010 260.280 -21.825
202012 -15.715 260.474 -20.148
202103 18.397 264.877 23.195
202106 -13.934 271.696 -17.127
202109 -14.393 274.310 -17.522
202112 -17.437 278.802 -20.886
202203 -20.907 287.504 -24.285
202206 -17.905 296.311 -20.180
202209 -15.891 296.808 -17.880
202212 -14.622 296.797 -16.452
202303 -16.583 301.836 -18.347
202306 -14.058 305.109 -15.387
202309 -13.238 307.789 -14.363
202312 -11.882 306.746 -12.936
202403 -39.001 312.332 -41.701
202406 -10.076 314.175 -10.710
202409 -14.374 315.301 -15.224
202412 -15.016 315.605 -15.889
202503 -16.571 319.799 -17.304
202506 -14.122 322.561 -14.621
202509 -15.042 324.800 -15.466
202512 -13.144 324.054 -13.545
202603 -14.967 330.213 -15.136
202606 -12.738 333.952 -12.738

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Rhythm Pharmaceuticals (MEX:RYTM) Overvalued in 2026?

Based on GuruFocus' analysis, Rhythm Pharmaceuticals stock appears to be undervalued. The current stock price of MXN1,866.76 is trading 8.3% below its estimated GF Value™ of MXN2,035.63.

Key valuation signals for MEX:RYTM:

  • Shiller PE Ratio:
  • GF Value™: MXN2,035.63 vs. price of MXN1,866.76 (8.3% below fair value)
  • GF Score™: 57/100 with 3 warning signs

No single metric tells the full story. See the MEX:RYTM stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Rhythm Pharmaceuticals Business Description

Other Exchanges RYTM:USA1RV:Germany
Address 222 Berkeley Street, 12th Floor, Boston, MA, USA, 02116
Rhythm Pharmaceuticals Inc is a commercial-stage biopharmaceutical company engaged in the development and commercialization of therapies for patients with rare neuroendocrine diseases. The company is focused on advancing its melanocortin-4 receptor (MC4R) agonists, including its main asset, IMCIVREE (setmelanotide), as a precision medicine designed to treat hyperphagia and severe obesity caused by rare MC4R pathway diseases. In addition, it has two early-stage investigational MC4R agonists in clinical development, RM-718 and bivamelagon, designed not to cause hyperpigmentation. The company is also focused on advancing potential candidates for congenital hyperinsulinism. It currently operates in two business segments: the United States, which generates maximum revenue, and International.
57GF Score

Get the complete analysis for MEX:RYTM

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN1,866.76
Price
MXN2,035.63
GF Value