ADPT (Adaptive Biotechnologies) Profitability Rank: 3 (As of Mar. 2026) — 50% Above Median

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ADPT Adaptive Biotechnologies Corp ADPT
64 GF Score
Price $25.46
GF Value $10.56
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Adaptive Biotechnologies Profitability Rank?

Adaptive Biotechnologies ADPT +2.09% 64 Profitability Rank is 3 as of Mar. 2026, which is 50% above its 10-year median of 2.00. GuruFocus rates ADPT with a GF Score™ of 64/100 and a GF Value™ of $10.56 (Significantly Overvalued). The stock has 5 warning signs investors should review.

Adaptive Biotechnologies has the Profitability Rank of 3. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Adaptive Biotechnologies's Operating Margin % for the quarter that ended in Mar. 2026 was -27.10%. As of today, Adaptive Biotechnologies's Piotroski F-Score is 5.


Adaptive Biotechnologies Profitability Rank Related Terms


ADPT vs GRAL, VCYT, RDNT: Profitability Rank Comparison

For the Diagnostics & Research subindustry, Adaptive Biotechnologies's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Adaptive Biotechnologies Profitability Rank vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Adaptive Biotechnologies's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Adaptive Biotechnologies's Profitability Rank falls into.


ADPT
64GF Score
Adaptive Biotechnologies Corp ADPT
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Adaptive Biotechnologies Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Adaptive Biotechnologies has the Profitability Rank of 3. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Adaptive Biotechnologies's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-19.206 / 70.874
=-27.10 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Adaptive Biotechnologies has an F-score of 5 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Good Sign:

Adaptive Biotechnologies Corp operating margin is expanding. Margin expansion is usually a good sign.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 3 mean?
Adaptive Biotechnologies (ADPT) has a Profitability Rank of 3 as of Mar. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Adaptive Biotechnologies and its competitors. This is 50% above median its historical median of 2.00. Over the past decade, Adaptive Biotechnologies' Profitability Rank has ranged from 1.00 to 3.00.
Is Adaptive Biotechnologies' Profitability Rank too high?
Adaptive Biotechnologies' current Profitability Rank of 3 is 50% above median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 3.00. Overall, Adaptive Biotechnologies has a GF Score™ of 64/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Adaptive Biotechnologies' Profitability Rank compare to GRAL and VCYT?
Adaptive Biotechnologies' Profitability Rank of 3 can be compared against companies in the Medical Diagnostics & Research industry. Historically, Adaptive Biotechnologies' own Profitability Rank has ranged from 1.00 to 3.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Medical Diagnostics & Research company?
A good Profitability Rank depends on the Medical Diagnostics & Research industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Adaptive Biotechnologies and its competitors. Adaptive Biotechnologies's current Profitability Rank is 3, which is 50% above median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Adaptive Biotechnologies stock overvalued right now?
Based on GuruFocus' analysis, Adaptive Biotechnologies (ADPT) is currently considered Significantly Overvalued. The stock's GF Value™ is $10.56, compared to a current price of $25.46 — trading 141.1% above its estimated fair value. The current Profitability Rank is 3, which is 50% above median its 10-year median of 2.00. Adaptive Biotechnologies' overall GF Score™ is 64/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Adaptive Biotechnologies (ADPT), the current Profitability Rank is 3 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Adaptive Biotechnologies (ADPT) Overvalued in 2026?

Based on GuruFocus' analysis, Adaptive Biotechnologies stock appears to be overvalued. The current stock price of $25.46 is trading 141.1% above its estimated GF Value™ of $10.56. GuruFocus considers Adaptive Biotechnologies to be Significantly Overvalued.

Key valuation signals for ADPT:

  • Profitability Rank: 3 (50% above median its 10-year median of 2.00)
  • GF Value™: $10.56 vs. price of $25.46 (141.1% above fair value)
  • GF Score™: 64/100 with 5 warning signs

No single metric tells the full story. See the ADPT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Adaptive Biotechnologies Business Description

Other Exchanges 1HM:Germany
Address 1165 Eastlake Avenue East, Seattle, WA, USA, 98109
Adaptive Biotechnologies Corp is a company advancing the field of immune-driven medicine by harnessing the inherent biology of the adaptive immune system to transform the diagnosis and treatment of disease. Its clinical diagnostic product, clonoSEQ, is a test authorized by the FDA for the detection and monitoring of minimal residual disease (MRD) in patients with multiple myeloma (MM), B cell acute lymphoblastic leukemia (ALL) and chronic lymphocytic leukemia (CLL) and is also available as a CLIA-validated laboratory developed test (LDT) for patients with other lymphoid cancers. The company has two operating segments: Minimal Residual Disease and Immune Medicine. The company generates the majority of its revenue from the Minimal Residual Disease segment.
64GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$25.46
Price
$10.56
GF Value