HRMY (Harmony Biosciences Holdings) Profitability Rank: 8 (As of Jun. 2026) — 60% Above Median

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HRMY Harmony Biosciences Holdings Inc HRMY
95 GF Score
Price $39.61
GF Value $46.94
Valuation Modestly Undervalued
! 2 Warning Signs
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What is Harmony Biosciences Holdings Profitability Rank?

Harmony Biosciences Holdings HRMY +1.89% 95 Profitability Rank is 8 as of Jun. 2026, which is 60% above its 10-year median of 5.00. GuruFocus rates HRMY with a GF Score™ of 95/100 and a GF Value™ of $46.94 (Modestly Undervalued). The stock has 2 warning signs investors should review.

Harmony Biosciences Holdings has the Profitability Rank of 8. It has a higher profitability and may stay that way.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Harmony Biosciences Holdings's Operating Margin % for the quarter that ended in Jun. 2026 was 34.18%. As of today, Harmony Biosciences Holdings's Piotroski F-Score is 4.


Harmony Biosciences Holdings Profitability Rank Related Terms


HRMY vs SION, URGN, PVLA: Profitability Rank Comparison

For the Biotechnology subindustry, Harmony Biosciences Holdings's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Harmony Biosciences Holdings Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Harmony Biosciences Holdings's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Harmony Biosciences Holdings's Profitability Rank falls into.


HRMY
95GF Score
Harmony Biosciences Holdings Inc HRMY
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Harmony Biosciences Holdings Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Harmony Biosciences Holdings has the Profitability Rank of 8. It has a higher profitability and may stay that way.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Harmony Biosciences Holdings's Operating Margin % for the quarter that ended in Jun. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=89.316 / 261.28
=34.18 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Harmony Biosciences Holdings has an F-score of 4 indicating the company's financial situation is typical for a stable company.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

Good Sign:

Harmony Biosciences Holdings Inc operating margin is expanding. Margin expansion is usually a good sign.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 8 mean?
Harmony Biosciences Holdings (HRMY) has a Profitability Rank of 8 as of Jun. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Harmony Biosciences Holdings and its competitors. This is 60% above median its historical median of 5.00. Over the past decade, Harmony Biosciences Holdings' Profitability Rank has ranged from 1.00 to 8.00.
Is Harmony Biosciences Holdings' Profitability Rank too high?
Harmony Biosciences Holdings' current Profitability Rank of 8 is 60% above median its 10-year median of 5.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 8.00. Overall, Harmony Biosciences Holdings has a GF Score™ of 95/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Harmony Biosciences Holdings' Profitability Rank compare to SION and URGN?
Harmony Biosciences Holdings' Profitability Rank of 8 can be compared against companies in the Biotechnology industry. Historically, Harmony Biosciences Holdings' own Profitability Rank has ranged from 1.00 to 8.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Harmony Biosciences Holdings and its competitors. Harmony Biosciences Holdings's current Profitability Rank is 8, which is 60% above median its own 10-year median of 5.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Harmony Biosciences Holdings stock overvalued right now?
Based on GuruFocus' analysis, Harmony Biosciences Holdings (HRMY) is currently considered Modestly Undervalued. The stock's GF Value™ is $46.94, compared to a current price of $39.61 — trading 15.6% below its estimated fair value. The current Profitability Rank is 8, which is 60% above median its 10-year median of 5.00. Harmony Biosciences Holdings' overall GF Score™ is 95/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Harmony Biosciences Holdings (HRMY), the current Profitability Rank is 8 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Harmony Biosciences Holdings (HRMY) Overvalued in 2026?

Based on GuruFocus' analysis, Harmony Biosciences Holdings stock appears to be undervalued. The current stock price of $39.61 is trading 15.6% below its estimated GF Value™ of $46.94. GuruFocus considers Harmony Biosciences Holdings to be Modestly Undervalued.

Key valuation signals for HRMY:

  • Profitability Rank: 8 (60% above median its 10-year median of 5.00)
  • GF Value™: $46.94 vs. price of $39.61 (15.6% below fair value)
  • GF Score™: 95/100 with 2 warning signs

No single metric tells the full story. See the HRMY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Harmony Biosciences Holdings Business Description

Address 630 W. Germantown Pike, Suite 215, Plymouth Meeting, PA, USA, 19462
Harmony Biosciences Holdings Inc is a commercial-stage pharmaceutical company focused on developing and commercializing therapies for patients living with rare neurological diseases who have unmet medical needs. The company has one reportable segment: rare neurological diseases. Its product WAKIX (pitolisant) is a molecule with a novel mechanism of action specifically designed to increase histamine signaling in the brain by binding to H3 receptors and is used for the treatment of cataplexy in adult patients with narcolepsy. The other drug candidates in its pipeline are Pitolisant, HBS-102 (MCHR1 antagonist), BP1.15205 (orexin-2 receptor agonist), ZYN002 (cannabidiol gel), EPX-100 (clemizole hydrochloride), and EPX-200 (lorcaserin), among others.
95GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$39.61
Price
$46.94
GF Value