HRMY (Harmony Biosciences Holdings) ROE % Adjusted to Book Value: 14.91% (As of Jun. 2026)

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HRMY Harmony Biosciences Holdings Inc HRMY
94 GF Score
Price $38.74
GF Value $46.81
Valuation Modestly Undervalued
! 2 Warning Signs
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What is Harmony Biosciences Holdings ROE % Adjusted to Book Value?

Harmony Biosciences Holdings HRMY +1.35% 94 ROE % Adjusted to Book Value is 14.91% as of Jun. 2026. GuruFocus rates HRMY with a GF Score™ of 94/100 and a GF Value™ of $46.81 (Modestly Undervalued). The stock has 2 warning signs investors should review.

Harmony Biosciences Holdings's ROE % for the quarter that ended in Jun. 2026 was 31.60%. Harmony Biosciences Holdings's PB Ratio for the quarter that ended in Jun. 2026 was 2.12. Harmony Biosciences Holdings's ROE % Adjusted to Book Value for the quarter that ended in Jun. 2026 was 14.91%.


Harmony Biosciences Holdings ROE % Adjusted to Book Value Related Terms


Harmony Biosciences Holdings ROE % Adjusted to Book Value Historical Data

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The historical data trend for Harmony Biosciences Holdings's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Harmony Biosciences Holdings ROE % Adjusted to Book Value Chart

Harmony Biosciences Holdings Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial 1.81 7.56 7.54 8.67 8.37

Harmony Biosciences Holdings Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 9.06 13.32 4.25 8.20 14.91

HRMY vs SION, URGN, PVLA: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Harmony Biosciences Holdings's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Harmony Biosciences Holdings ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Harmony Biosciences Holdings's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Harmony Biosciences Holdings's ROE % Adjusted to Book Value falls into.


HRMY
94GF Score
Harmony Biosciences Holdings Inc HRMY
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Harmony Biosciences Holdings ROE % Adjusted to Book Value Calculation

Harmony Biosciences Holdings's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=20.75% / 2.48
=8.37%

Harmony Biosciences Holdings's ROE % Adjusted to Book Value for the quarter that ended in Jun. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=31.60% / 2.12
=14.91%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of 14.91% mean?
Harmony Biosciences Holdings (HRMY) has a ROE % Adjusted to Book Value of 14.91% as of Jun. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Harmony Biosciences Holdings and its competitors.
Is Harmony Biosciences Holdings' ROE % Adjusted to Book Value too high?
Harmony Biosciences Holdings' current ROE % Adjusted to Book Value is 14.91%. Overall, Harmony Biosciences Holdings has a GF Score™ of 94/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Harmony Biosciences Holdings' ROE % Adjusted to Book Value compare to SION and URGN?
Harmony Biosciences Holdings' ROE % Adjusted to Book Value of 14.91% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Harmony Biosciences Holdings and its competitors. Harmony Biosciences Holdings's current ROE % Adjusted to Book Value is 14.91%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Harmony Biosciences Holdings stock overvalued right now?
Based on GuruFocus' analysis, Harmony Biosciences Holdings (HRMY) is currently considered Modestly Undervalued. The stock's GF Value™ is $46.81, compared to a current price of $38.74 — trading 17.2% below its estimated fair value. The current ROE % Adjusted to Book Value is 14.91%. Harmony Biosciences Holdings' overall GF Score™ is 94/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Harmony Biosciences Holdings (HRMY), the current ROE % Adjusted to Book Value is 14.91% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Harmony Biosciences Holdings (HRMY) Overvalued in 2026?

Based on GuruFocus' analysis, Harmony Biosciences Holdings stock appears to be undervalued. The current stock price of $38.74 is trading 17.2% below its estimated GF Value™ of $46.81. GuruFocus considers Harmony Biosciences Holdings to be Modestly Undervalued.

Key valuation signals for HRMY:

  • ROE % Adjusted to Book Value: 14.91%
  • GF Value™: $46.81 vs. price of $38.74 (17.2% below fair value)
  • GF Score™: 94/100 with 2 warning signs

No single metric tells the full story. See the HRMY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Harmony Biosciences Holdings Business Description

Address 630 W. Germantown Pike, Suite 215, Plymouth Meeting, PA, USA, 19462
Harmony Biosciences Holdings Inc is a commercial-stage pharmaceutical company focused on developing and commercializing therapies for patients living with rare neurological diseases who have unmet medical needs. The company has one reportable segment: rare neurological diseases. Its product WAKIX (pitolisant) is a molecule with a novel mechanism of action specifically designed to increase histamine signaling in the brain by binding to H3 receptors and is used for the treatment of cataplexy in adult patients with narcolepsy. The other drug candidates in its pipeline are Pitolisant, HBS-102 (MCHR1 antagonist), BP1.15205 (orexin-2 receptor agonist), ZYN002 (cannabidiol gel), EPX-100 (clemizole hydrochloride), and EPX-200 (lorcaserin), among others.
94GF Score

Get the complete analysis for HRMY

ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$38.74
Price
$46.81
GF Value