LXEO (Lexeo Therapeutics) Profitability Rank: 1 (As of Jun. 2026) — Near Median

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LXEO Lexeo Therapeutics Inc LXEO
12 GF Score
Price $5.24
! 3 Warning Signs
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What is Lexeo Therapeutics Profitability Rank?

Lexeo Therapeutics LXEO +5.97% 12 Profitability Rank is 1 as of Jun. 2026, which is at its 10-year median of 1.00. GuruFocus rates LXEO with a GF Score™ of 12/100. The stock has 3 warning signs investors should review.

Lexeo Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Lexeo Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 was %. As of today, Lexeo Therapeutics's Piotroski F-Score is 3.


Lexeo Therapeutics Profitability Rank Related Terms


LXEO vs IKT, XFOR, DMAC: Profitability Rank Comparison

For the Biotechnology subindustry, Lexeo Therapeutics's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Lexeo Therapeutics Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Lexeo Therapeutics's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Lexeo Therapeutics's Profitability Rank falls into.


LXEO
12GF Score
Lexeo Therapeutics Inc LXEO
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Lexeo Therapeutics Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Lexeo Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Lexeo Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=-28.02 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Lexeo Therapeutics has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 1 mean?
Lexeo Therapeutics (LXEO) has a Profitability Rank of 1 as of Jun. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Lexeo Therapeutics and its competitors. This is near median its historical median of 1.00. Over the past decade, Lexeo Therapeutics' Profitability Rank has ranged from 1.00 to 1.00.
Is Lexeo Therapeutics' Profitability Rank too high?
Lexeo Therapeutics' current Profitability Rank of 1 is near median its 10-year median of 1.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 1.00. Overall, Lexeo Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Lexeo Therapeutics' Profitability Rank compare to IKT and XFOR?
Lexeo Therapeutics' Profitability Rank of 1 can be compared against companies in the Biotechnology industry. Historically, Lexeo Therapeutics' own Profitability Rank has ranged from 1.00 to 1.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Lexeo Therapeutics and its competitors. Lexeo Therapeutics's current Profitability Rank is 1, which is near median its own 10-year median of 1.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Lexeo Therapeutics stock overvalued right now?
Lexeo Therapeutics (LXEO) has a current Profitability Rank of 1. The current Profitability Rank is 1, which is near median its 10-year median of 1.00. Lexeo Therapeutics' overall GF Score™ is 12/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Lexeo Therapeutics (LXEO), the current Profitability Rank is 1 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Lexeo Therapeutics Business Description

Address 345 Park Avenue South, Floor 6, New York, NY, USA, 10010
Lexeo Therapeutics Inc is a clinical-stage genetic medicine company engaged in the development of gene therapy candidates targeting the underlying genetic causes of cardiovascular diseases. The company is advancing a portfolio of programs focused on conditions such as Friedreich ataxia, cardiomyopathy, plakophilin-2, or PKP2, and arrhythmogenic cardiomyopathy, with its lead candidates including LX2006 and LX2020. Its therapies utilize AAV-based vectors designed to deliver functional genes to cardiac cells to restore normal function and address high unmet medical needs.
12GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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