MGX (Metagenomi Therapeutics) Profitability Rank: 1 (As of Jun. 2026) — Near Median

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MGX Metagenomi Therapeutics Inc MGX
8 GF Score
Price $1.17
GF Value $0.75
Valuation Significantly Overvalued
! 3 Warning Signs
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What is Metagenomi Therapeutics Profitability Rank?

Metagenomi Therapeutics MGX -0.43% 8 Profitability Rank is 1 as of Jun. 2026, which is at its 10-year median of 1.00. GuruFocus rates MGX with a GF Score™ of 8/100 and a GF Value™ of $0.75 (Significantly Overvalued). The stock has 3 warning signs investors should review.

Metagenomi Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way. It is rated on a scale of 1 to 10 and is based on these factors:

1. Operating Margin %
2. Piotroski F-Score
3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.
4. Consistency of the profitability
5. Predictability Rank

A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Metagenomi Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 was 11,195.72%. As of today, Metagenomi Therapeutics's Piotroski F-Score is 1.


Metagenomi Therapeutics Profitability Rank Related Terms


MGX vs TVGN, VERU, GRCE: Profitability Rank Comparison

For the Biotechnology subindustry, Metagenomi Therapeutics's Profitability Rank, along with its competitors' market caps and Profitability Rank data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Metagenomi Therapeutics Profitability Rank vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Metagenomi Therapeutics's Profitability Rank distribution charts can be found below:

* The bar in red indicates where Metagenomi Therapeutics's Profitability Rank falls into.


MGX
8GF Score
Metagenomi Therapeutics Inc MGX
Profitability Rank is just one metric. See GF Score™, valuation, warning signs, and more.
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Metagenomi Therapeutics Profitability Rank Calculation

GuruFocus Profitability Rank ranks how profitable a company is and how likely the company's business will stay that way.

The rank is rated on a scale of 1 to 10. A higher score indicates superior profitability, with companies rated 7 or above considered to have more robust and sustainable profit generation. Conversely, a score of 3 or lower suggests challenges in generating consistent profits.

Metagenomi Therapeutics has the Profitability Rank of 1. It has had trouble to make a profit.

Profitability Rank is not directly related to the Financial Strength. But if a company is consistently profitable, its financial strength will be stronger.

Profitability Rank is based on these factors:

1. Operating Margin %

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Metagenomi Therapeutics's Operating Margin % for the quarter that ended in Jun. 2026 is calculated as:

Operating Margin %=Operating Income (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=-28.773 / -0.257
=11,195.72 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2. Piotroski F-Score

Warning Sign:

Piotroski F-Score of 1 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 8 or 9
Bad or low score = 0 or 1

Metagenomi Therapeutics has an F-score of 1. It is a bad or low score, which usually implies poor business operation.

3. Trend of the Operating Margin % (5-year average). The company with an uptrend profit margin has a higher rank.

4. Consistency of the profitability

5. Predictability Rank

Frequently Asked Questions Learn more about Profitability Rank →
What does a Profitability Rank of 1 mean?
Metagenomi Therapeutics (MGX) has a Profitability Rank of 1 as of Jun. 2026. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Metagenomi Therapeutics and its competitors. This is near median its historical median of 1.00. Over the past decade, Metagenomi Therapeutics' Profitability Rank has ranged from 1.00 to 1.00.
Is Metagenomi Therapeutics' Profitability Rank too high?
Metagenomi Therapeutics' current Profitability Rank of 1 is near median its 10-year median of 1.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 1.00. Overall, Metagenomi Therapeutics has a GF Score™ of 8/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Metagenomi Therapeutics' Profitability Rank compare to TVGN and VERU?
Metagenomi Therapeutics' Profitability Rank of 1 can be compared against companies in the Biotechnology industry. Historically, Metagenomi Therapeutics' own Profitability Rank has ranged from 1.00 to 1.00 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Profitability Rank for a Biotechnology company?
A good Profitability Rank depends on the Biotechnology industry context. However, Profitability Rank should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Profitability Rank mean?
A high Profitability Rank can signal that a stock is expensive relative to its fundamentals. Profitability and Growth ranks a company based on its profit margins and earnings growth. View historical data on Metagenomi Therapeutics and its competitors. Metagenomi Therapeutics's current Profitability Rank is 1, which is near median its own 10-year median of 1.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Metagenomi Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Metagenomi Therapeutics (MGX) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.75, compared to a current price of $1.17 — trading 56% above its estimated fair value. The current Profitability Rank is 1, which is near median its 10-year median of 1.00. Metagenomi Therapeutics' overall GF Score™ is 8/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Profitability Rank calculated?
Profitability Rank is calculated from a company's financial statements. For Metagenomi Therapeutics (MGX), the current Profitability Rank is 1 as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Metagenomi Therapeutics (MGX) Overvalued in 2026?

Based on GuruFocus' analysis, Metagenomi Therapeutics stock appears to be overvalued. The current stock price of $1.17 is trading 56% above its estimated GF Value™ of $0.75. GuruFocus considers Metagenomi Therapeutics to be Significantly Overvalued.

Key valuation signals for MGX:

  • Profitability Rank: 1 (near median its 10-year median of 1.00)
  • GF Value™: $0.75 vs. price of $1.17 (56% above fair value)
  • GF Score™: 8/100 with 3 warning signs

No single metric tells the full story. See the MGX stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Metagenomi Therapeutics Business Description

Address 5959 Horton Street, 7th Floor, Emeryville, CA, USA, 94608
Metagenomi Therapeutics Inc is an vivo genome editing company capitalizing on its proprietary technologies to create curative genetic medicines for patients. The company leverages machine learning and artificial intelligence to enhance its signature gene editing systems. MGX-001 is its, wholly-owned development program in hemophilia A, where the company have demonstrated targeted genome editing and durable gene expression from a one-time treatment in non-human primates (NHPs) and an overall profile potentially competitive with best-in-class treatment options. MGX-001 is designed to provide curative, life-long protection from bleeding events and joint damage in adults and children with hemophilia A from a single administration.
8GF Score

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Profitability Rank is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.17
Price
$0.75
GF Value