Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
uniQure NVLTS:0EE0 +13.28%43 Return-on-Tangible-Asset is -40.98% as of Jun. 2026. GuruFocus rates LTS:0EE0 with a GF Score™ of 43/100 and a GF Value™ of $7.30 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,415 Biotechnology companies, uniQure NV ranks better than 52.72% on this metric.
Return-on-Tangible-Asset is calculated as Net Income divided by its average total tangible assets. Total tangible assets equals to Total Assets minus Intangible Assets. uniQure NV's annualizedNet Income for the quarter that ended in Jun. 2026 was $-324.24 Mil. uniQure NV's average total tangible assets for the quarter that ended in Jun. 2026 was $791.16 Mil. Therefore, uniQure NV's annualized Return-on-Tangible-Asset for the quarter that ended in Jun. 2026 was -40.98%.
The historical rank and industry rank for uniQure NV's Return-on-Tangible-Asset or its related term are showing as below:
LTS:0EE0'
s Return-on-Tangible-Asset Range Over the Past 10 Years
Min: -45.18 Med: -34.27 Max: 62.46
Current: -35.21
During the past 13 years, uniQure NV's highest Return-on-Tangible-Asset was 62.46%. The lowest was -45.18%. And the median was -34.27%.
LTS:0EE0's Return-on-Tangible-Asset is ranked better than 52.72% of 1415
companies
in the Biotechnology industry
Industry Median: -35.49
vs LTS:0EE0: -35.21
Return-on-Tangible-Asset measures the rate of return on the average total tangible assets (total assets minus intangible assets). Tangible means physical in nature. Intangible Assets are assets that are not physical in nature, and typically "derive their value from legal or intellectual rights." Return-on-Tangible-Asset measures a firm's efficiency at generating profits from its tangible assets. It shows how well a company uses what it has to generate earnings. Return-on-Tangible-Assets can vary drastically across industries. Therefore, Return-on-Tangible-Asset should not be used to compare companies in different industries.
Be Aware
Like ROE and ROA, Return-on-Tangible-Asset is calculated with only 12 months data. Fluctuations in the companys earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. Return-on-Tangible-Asset can be affected by events such as stock buyback or issuance, and by a companys tax rate and its interest payment. Return-on-Tangible-Asset may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).
Many analysts argue the higher return the better. Buffett states that really high Return-on-Tangible-Asset may indicate vulnerability in the durability of the competitive advantage.
uniQure NV Return-on-Tangible-Asset Related Terms
uniQure NV Return-on-Tangible-Asset Historical Data
* Premium members only.
The historical data trend for uniQure NV's Return-on-Tangible-Asset can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
LTS:0EE0 vs ATAI, RARE, CLDX: Return-on-Tangible-Asset Comparison
For the Biotechnology subindustry, uniQure NV's Return-on-Tangible-Asset, along with its competitors' market caps and Return-on-Tangible-Asset data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
uniQure NV Return-on-Tangible-Asset vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, uniQure NV's Return-on-Tangible-Asset distribution charts can be found below:
* The bar in red indicates where uniQure NV's Return-on-Tangible-Asset falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Asset, the net income of the last fiscal year and the average total tangible assets over the fiscal year are used. In calculating the quarterly data,
the Net Income data used here is four times the quarterly (Jun. 2026) net income data.
What does a Return-on-Tangible-Asset of -40.98% mean?
uniQure NV (LTS:0EE0) has a Return-on-Tangible-Asset of -40.98% as of Jun. 2026. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on uniQure NV and its competitors. According to the industry distribution chart, uniQure NV ranks #669 out of 1415 companies in the Biotechnology industry, placing it in the top 47.3%.
Is uniQure NV's Return-on-Tangible-Asset too high?
uniQure NV's current Return-on-Tangible-Asset is -40.98%. Based on the distribution chart, uniQure NV ranks #669 out of 1415 companies in the Biotechnology industry, which is above the industry midpoint. Overall, uniQure NV has a GF Score™ of 43/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does uniQure NV's Return-on-Tangible-Asset compare to ATAI and RARE?
According to the Biotechnology industry distribution chart, uniQure NV ranks #669 out of 1415 companies for Return-on-Tangible-Asset. This puts uniQure NV in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Asset for a Biotechnology company?
A good Return-on-Tangible-Asset depends on the Biotechnology industry context. However, Return-on-Tangible-Asset should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Asset mean?
A high Return-on-Tangible-Asset can signal that a stock is expensive relative to its fundamentals. Return on tangible assets is the ratio of current-period net income to average two-period tangible assets. View historical data on uniQure NV and its competitors. uniQure NV's current Return-on-Tangible-Asset is -40.98%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is uniQure NV stock overvalued right now?
Based on GuruFocus' analysis, uniQure NV (LTS:0EE0) is currently considered Significantly Overvalued. The stock's GF Value™ is $7.30, compared to a current price of $40.60 — trading 456.2% above its estimated fair value. The current Return-on-Tangible-Asset is -40.98%. uniQure NV's overall GF Score™ is 43/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Asset calculated?
Return-on-Tangible-Asset is calculated from a company's financial statements. For uniQure NV (LTS:0EE0), the current Return-on-Tangible-Asset is -40.98% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is uniQure NV (LTS:0EE0) Overvalued in 2026?
Based on GuruFocus' analysis, uniQure NV stock appears to be overvalued.
The current stock price of $40.60 is trading 456.2% above its estimated GF Value™ of $7.30.
GuruFocus considers uniQure NV to be Significantly Overvalued.
Key valuation signals for LTS:0EE0:
Return-on-Tangible-Asset: -40.98%
GF Value™: $7.30 vs. price of $40.60 (456.2% above fair value)
No single metric tells the full story. See the LTS:0EE0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
uniQure NV is a gene therapy company. It develops treatments and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntington's disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases. Its program and pipeline involves: Huntington's Disease, Temporal Lobe Epilepsy (TLE), Fabry Disease, ALS (SOD1), Hemophilia B, Clinical Trials, and Research Programs.
43GF Score
Get the complete analysis for LTS:0EE0
Return-on-Tangible-Asset is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
LTS:0EE0 has been successfully added to your 
