uniQure NV (LTS:0EE0) 3-Year RORE % : -19.39% (As of Mar. 2026)

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Director of Data and Quant Analytics at GuruFocus
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Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

LTS:0EE0 uniQure NV LTS:0EE0
43 GF Score
Price $40.30
GF Value $5.84
Valuation Significantly Overvalued
! 5 Warning Signs
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What is uniQure NV 3-Year RORE %?

uniQure NV LTS:0EE0 +2.18% 43 3-Year RORE % is -19.39 as of Mar. 2026. GuruFocus rates LTS:0EE0 with a GF Score™ of 43/100 and a GF Value™ of $5.84 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 1,291 Biotechnology companies, uniQure NV ranks worse than 58.09% on this metric.

Return on Retained Earnings (RORE) is an indicator of a company's growth potential, it shows how much a company earns by reinvesting its retained earnings, i.e. profits after dividend payments. uniQure NV's 3-Year RORE % for the quarter that ended in Mar. 2026 was -19.39%.

The industry rank for uniQure NV's 3-Year RORE % or its related term are showing as below:

LTS:0EE0's 3-Year RORE % is ranked worse than
58.09% of 1291 companies
in the Biotechnology industry
Industry Median: -11.44 vs LTS:0EE0: -19.39

uniQure NV  (LTS:0EE0) 3-Year RORE % Explanation

Return on Retained Earnings (RORE) is important to investors because it reveals a company's efficiency and growth potential. A higher RORE indicates a higher return. A high RORE indicates that the company should reinvest profits into the business. A lower RORE suggests that the company should distribute profits to shareholders by paying out dividends, since those dollars aren't generating much additional growth for the company.

There are a several different ways to arrive at the Return on Retained Earnings. The simplest way to calculate it is by using published information on Earnings per Share (EPS) and Dividend per Share (DPS) over a selected period. Here, 3-year period is chosen.

Be Aware

Please keep in mind that the RORE is relative to the nature of the business and its competitors. If another company in the same sector is producing a lower return on retained earnings, it doesn’t necessarily mean it’s a bad investment. It may just suggest the company is older and no longer in a high growth stage. At such a stage in the business cycle, it would be expected to see a lower RORE and higher dividend payout.


uniQure NV 3-Year RORE % Related Terms


uniQure NV 3-Year RORE % Historical Data

* Premium members only.

The historical data trend for uniQure NV's 3-Year RORE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

uniQure NV 3-Year RORE % Chart

uniQure NV Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
3-Year RORE %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 961.90 6.85 609.05 15.72 -20.39

uniQure NV Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
3-Year RORE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 7.53 -0.15 -2.90 -20.39 -19.39

LTS:0EE0 vs ALMS, ARQT, DYN: 3-Year RORE % Comparison

For the Biotechnology subindustry, uniQure NV's 3-Year RORE %, along with its competitors' market caps and 3-Year RORE % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


uniQure NV 3-Year RORE % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, uniQure NV's 3-Year RORE % distribution charts can be found below:

* The bar in red indicates where uniQure NV's 3-Year RORE % falls into.


LTS:0EE0
43GF Score
uniQure NV LTS:0EE0
3-Year RORE % is just one metric. See GF Score™, valuation, warning signs, and more.
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uniQure NV 3-Year RORE % Calculation

uniQure NV's 3-Year RORE % for the quarter that ended in Mar. 2026 is calculated as:

3-Year RORE %=( Most Recent EPS (Diluted)- First Period EPS (Diluted) )/( Cumulative EPS (Diluted) for 3-year -Cumulative Dividends per Share for 3-year )
=( -3.48--6.21 )/( -14.08-0 )
=2.73/-14.08
=-19.39 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of 3-Year RORE %, the most recent and first period EPS (Diluted) is the trailing twelve months (TTM) data ended in Mar. 2026 and 3-year before.

Frequently Asked Questions Learn more about 3-Year RORE % →
What does a 3-Year RORE % of -19.39 mean?
uniQure NV (LTS:0EE0) has a 3-Year RORE % of -19.39 as of Mar. 2026. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on uniQure NV and its competitors. According to the industry distribution chart, uniQure NV ranks #750 out of 1291 companies in the Biotechnology industry, placing it in the top 58.1%.
Is uniQure NV's 3-Year RORE % too high?
uniQure NV's current 3-Year RORE % is -19.39. Based on the distribution chart, uniQure NV ranks #750 out of 1291 companies in the Biotechnology industry, which is below the industry midpoint. Overall, uniQure NV has a GF Score™ of 43/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does uniQure NV's 3-Year RORE % compare to ALMS and ARQT?
According to the Biotechnology industry distribution chart, uniQure NV ranks #750 out of 1291 companies for 3-Year RORE %. This places uniQure NV in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year RORE % for a Biotechnology company?
A good 3-Year RORE % depends on the Biotechnology industry context. However, 3-Year RORE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year RORE % mean?
A high 3-Year RORE % can signal that a stock is expensive relative to its fundamentals. 3-Year RORE % shows how much a company earns by reinvesting its retained earnings in 3-year. View historical data on uniQure NV and its competitors. uniQure NV's current 3-Year RORE % is -19.39. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is uniQure NV stock overvalued right now?
Based on GuruFocus' analysis, uniQure NV (LTS:0EE0) is currently considered Significantly Overvalued. The stock's GF Value™ is $5.84, compared to a current price of $40.30 — trading 590.1% above its estimated fair value. The current 3-Year RORE % is -19.39. uniQure NV's overall GF Score™ is 43/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year RORE % calculated?
3-Year RORE % is calculated from a company's financial statements. For uniQure NV (LTS:0EE0), the current 3-Year RORE % is -19.39 as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is uniQure NV (LTS:0EE0) Overvalued in 2026?

Based on GuruFocus' analysis, uniQure NV stock appears to be overvalued. The current stock price of $40.30 is trading 590.1% above its estimated GF Value™ of $5.84. GuruFocus considers uniQure NV to be Significantly Overvalued.

Key valuation signals for LTS:0EE0:

  • 3-Year RORE %: -19.39
  • GF Value™: $5.84 vs. price of $40.30 (590.1% above fair value)
  • GF Score™: 43/100 with 5 warning signs

No single metric tells the full story. See the LTS:0EE0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


uniQure NV Business Description

Address Paasheuvelweg 25, Amsterdam, NH, NLD, 1105 BP
uniQure NV is a gene therapy company. It develops treatments and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntington's disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases. Its program and pipeline involves: Huntington's Disease, Temporal Lobe Epilepsy (TLE), Fabry Disease, ALS (SOD1), Hemophilia B, Clinical Trials, and Research Programs.
43GF Score

Get the complete analysis for LTS:0EE0

3-Year RORE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$40.30
Price
$5.84
GF Value