CGEN (Compugen) Return-on-Tangible-Equity: -30.97% (As of Mar. 2026)


CGEN Compugen Ltd CGEN
60 GF Score
Price $2.14
GF Value $5.21
Valuation Possible Value Trap
! 4 Warning Signs
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What is Compugen Return-on-Tangible-Equity?

Compugen CGEN -0.47% 60 Return-on-Tangible-Equity is -30.97% as of Mar. 2026. GuruFocus rates CGEN with a GF Score™ of 60/100 and a GF Value™ of $5.21 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 1,199 Biotechnology companies, Compugen ranks better than 95.33% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Compugen's annualized net income for the quarter that ended in Mar. 2026 was $-30.68 Mil. Compugen's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $99.04 Mil. Therefore, Compugen's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -30.97%.

The historical rank and industry rank for Compugen's Return-on-Tangible-Equity or its related term are showing as below:

CGEN' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -79.87   Med: -37.06   Max: 49.9
Current: 49.9

During the past 13 years, Compugen's highest Return-on-Tangible-Equity was 49.90%. The lowest was -79.87%. And the median was -37.06%.

CGEN's Return-on-Tangible-Equity is ranked better than
95.33% of 1199 companies
in the Biotechnology industry
Industry Median: -42.4 vs CGEN: 49.90

Compugen  (NAS:CGEN) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Compugen Return-on-Tangible-Equity Related Terms


Compugen Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Compugen's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Compugen Return-on-Tangible-Equity Chart

Compugen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial Premium Member Only Premium Member Only -30.20 -36.55 -26.19 -23.63 44.84

Compugen Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -51.28 -54.71 -59.34 310.30 -30.97

CGEN vs VRTX, REGN, ALNY: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Compugen's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Compugen Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Compugen's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Compugen's Return-on-Tangible-Equity falls into.


CGEN
60GF Score
Compugen Ltd CGEN
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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Compugen Return-on-Tangible-Equity Calculation

Compugen's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=35.343/( (54.914+102.731 )/ 2 )
=35.343/78.8225
=44.84 %

Compugen's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-30.676/( (102.731+95.353)/ 2 )
=-30.676/99.042
=-30.97 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -30.97% mean?
Compugen (CGEN) has a Return-on-Tangible-Equity of -30.97% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Compugen and its competitors. According to the industry distribution chart, Compugen ranks #56 out of 1199 companies in the Biotechnology industry, placing it in the top 4.7%.
Is Compugen's Return-on-Tangible-Equity too high?
Compugen's current Return-on-Tangible-Equity is -30.97%. Based on the distribution chart, Compugen ranks #56 out of 1199 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Compugen has a GF Score™ of 60/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Compugen's Return-on-Tangible-Equity compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Compugen ranks #56 out of 1199 companies for Return-on-Tangible-Equity. This places Compugen in the top 5% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Compugen and its competitors. Compugen's current Return-on-Tangible-Equity is -30.97%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Compugen stock overvalued right now?
Based on GuruFocus' analysis, Compugen (CGEN) is currently considered Possible Value Trap. The stock's GF Value™ is $5.21, compared to a current price of $2.14 — trading 59% below its estimated fair value. The current Return-on-Tangible-Equity is -30.97%. Compugen's overall GF Score™ is 60/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Compugen (CGEN), the current Return-on-Tangible-Equity is -30.97% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Compugen (CGEN) Overvalued in 2026?

Based on GuruFocus' analysis, Compugen stock appears to be undervalued. The current stock price of $2.14 is trading 59% below its estimated GF Value™ of $5.21. GuruFocus considers Compugen to be Possible Value Trap.

Key valuation signals for CGEN:

  • Return-on-Tangible-Equity: -30.97%
  • GF Value™: $5.21 vs. price of $2.14 (59% below fair value)
  • GF Score™: 60/100 with 4 warning signs

No single metric tells the full story. See the CGEN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Compugen Business Description

Other Exchanges CGEN:Israel
Address 26 Harokmim Street, Building D, Azrieli Center, Holon, ISR, 5885849
Compugen Ltd is a clinical-stage therapeutic discovery and development company utilizing Unigen, its AI/ML-powered computational discovery capabilities, to identify novel drug targets and new biological pathways to develop therapeutics in the field of cancer immunotherapy. Its immuno-oncology pipeline consists of four clinical-stage programs: COM701, COM902, rilvegostomig, and GS-0321 (previously COM503), targeting immune checkpoints the company discovered computationally. The company's revenues are generated mainly from collaborative and license agreements. Geographically, it generates maximum revenue from the United Kingdom, and the rest from the United States.
60GF Score

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Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.14
Price
$5.21
GF Value