CGEN (Compugen) Shiller PE Ratio: (As of Sep. 21, 2026)

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Director of Data and Quant Analytics at GuruFocus
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CGEN Compugen Ltd CGEN
59 GF Score
Price $2.48
GF Value $5.31
Valuation Possible Value Trap
! 5 Warning Signs
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What is Compugen Shiller PE Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


Compugen  (NAS:CGEN) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


Compugen Shiller PE Ratio Related Terms


Compugen Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for Compugen's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Compugen Shiller PE Ratio Chart

Compugen Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
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Compugen Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
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CGEN vs VRTX, REGN, MRNA: Shiller PE Ratio Comparison

For the Biotechnology subindustry, Compugen's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Compugen Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Compugen's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where Compugen's Shiller PE Ratio falls into.


CGEN
59GF Score
Compugen Ltd CGEN
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Compugen Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

Compugen's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, Compugen's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-0.074/333.9520*333.9520
=-0.074

Current CPI (Jun. 2026) = 333.9520.

Compugen Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 -0.150 241.428 -0.207
201612 -0.170 241.432 -0.235
201703 -0.170 243.801 -0.233
201706 -0.180 244.955 -0.245
201709 -0.190 246.819 -0.257
201712 -0.180 246.524 -0.244
201803 0.002 249.554 0.003
201806 -0.196 251.989 -0.259
201809 -0.054 252.439 -0.072
201812 -0.158 251.233 -0.210
201903 -0.140 254.202 -0.184
201906 -0.097 256.143 -0.127
201909 -0.099 256.759 -0.129
201912 -0.096 256.974 -0.124
202003 -0.101 258.115 -0.131
202006 -0.077 257.797 -0.099
202009 -0.093 260.280 -0.120
202012 -0.103 260.474 -0.132
202103 -0.118 264.877 -0.149
202106 -0.113 271.696 -0.139
202109 -0.073 274.310 -0.089
202112 -0.101 278.802 -0.121
202203 -0.112 287.504 -0.130
202206 -0.106 296.311 -0.119
202209 -0.136 296.808 -0.153
202212 -0.036 296.797 -0.040
202303 -0.108 301.836 -0.119
202306 -0.106 305.109 -0.116
202309 -0.112 307.789 -0.121
202312 0.110 306.746 0.120
202403 -0.081 312.332 -0.087
202406 -0.024 314.175 -0.025
202409 0.014 315.301 0.015
202412 -0.068 315.605 -0.072
202503 -0.078 319.799 -0.081
202506 -0.079 322.561 -0.081
202509 -0.075 324.800 -0.077
202512 0.600 324.054 0.619
202603 -0.081 330.213 -0.082
202606 -0.074 333.952 -0.074

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is Compugen (CGEN) Overvalued in 2026?

Based on GuruFocus' analysis, Compugen stock appears to be undervalued. The current stock price of $2.48 is trading 53.4% below its estimated GF Value™ of $5.31. GuruFocus considers Compugen to be Possible Value Trap.

Key valuation signals for CGEN:

  • Shiller PE Ratio:
  • GF Value™: $5.31 vs. price of $2.48 (53.4% below fair value)
  • GF Score™: 59/100 with 5 warning signs

No single metric tells the full story. See the CGEN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Compugen Business Description

Other Exchanges CGEN:Israel
Address 26 Harokmim Street, Building D, Azrieli Center, Holon, ISR, 5885849
Compugen Ltd is a clinical-stage therapeutic discovery and development company utilizing Unigen, its AI/ML-powered computational discovery capabilities, to identify novel drug targets and new biological pathways to develop therapeutics in the field of cancer immunotherapy. Its immuno-oncology pipeline consists of four clinical-stage programs: COM701, COM902, rilvegostomig, and GS-0321 (previously COM503), targeting immune checkpoints the company discovered computationally. The company's revenues are generated mainly from collaborative and license agreements. Geographically, it generates maximum revenue from the United Kingdom, and the rest from the United States.
59GF Score

Get the complete analysis for CGEN

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.48
Price
$5.31
GF Value