INAB (IN8bio) Return-on-Tangible-Equity: -80.89% (As of Mar. 2026)


INAB IN8bio Inc INAB
24 GF Score
Price $1.43
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What is IN8bio Return-on-Tangible-Equity?

IN8bio INAB +0.35% 24 Return-on-Tangible-Equity is -80.89% as of Mar. 2026. GuruFocus rates INAB with a GF Score™ of 24/100. Among 1,199 Biotechnology companies, IN8bio ranks worse than 73.14% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. IN8bio's annualized net income for the quarter that ended in Mar. 2026 was $-20.36 Mil. IN8bio's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $25.17 Mil. Therefore, IN8bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -80.89%.

The historical rank and industry rank for IN8bio's Return-on-Tangible-Equity or its related term are showing as below:

INAB' s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -238.74   Med: -94.43   Max: -44.78
Current: -102.44

During the past 8 years, IN8bio's highest Return-on-Tangible-Equity was -44.78%. The lowest was -238.74%. And the median was -94.43%.

INAB's Return-on-Tangible-Equity is ranked worse than
73.14% of 1199 companies
in the Biotechnology industry
Industry Median: -42.4 vs INAB: -102.44

IN8bio  (NAS:INAB) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


IN8bio Return-on-Tangible-Equity Related Terms


IN8bio Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for IN8bio's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

IN8bio Return-on-Tangible-Equity Chart

IN8bio Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial -51.87 -93.64 -125.90 -154.44 -92.49

IN8bio Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -156.59 -139.96 -108.46 -97.03 -80.89

INAB vs GDTC, LEXX, TRAW: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, IN8bio's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


IN8bio Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, IN8bio's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where IN8bio's Return-on-Tangible-Equity falls into.


INAB
24GF Score
IN8bio Inc INAB
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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IN8bio Return-on-Tangible-Equity Calculation

IN8bio's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-19.44/( (14.478+27.558 )/ 2 )
=-19.44/21.018
=-92.49 %

IN8bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-20.36/( (27.558+22.781)/ 2 )
=-20.36/25.1695
=-80.89 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -80.89% mean?
IN8bio (INAB) has a Return-on-Tangible-Equity of -80.89% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on IN8bio and its competitors. According to the industry distribution chart, IN8bio ranks #877 out of 1199 companies in the Biotechnology industry, placing it in the top 73.1%.
Is IN8bio's Return-on-Tangible-Equity too high?
IN8bio's current Return-on-Tangible-Equity is -80.89%. Based on the distribution chart, IN8bio ranks #877 out of 1199 companies in the Biotechnology industry, which is below the industry midpoint. Overall, IN8bio has a GF Score™ of 24/100, reflecting its overall financial health beyond just this single metric.
How does IN8bio's Return-on-Tangible-Equity compare to GDTC and LEXX?
According to the Biotechnology industry distribution chart, IN8bio ranks #877 out of 1199 companies for Return-on-Tangible-Equity. This places IN8bio in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on IN8bio and its competitors. IN8bio's current Return-on-Tangible-Equity is -80.89%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is IN8bio stock overvalued right now?
IN8bio (INAB) has a current Return-on-Tangible-Equity of -80.89%. The current Return-on-Tangible-Equity is -80.89%. IN8bio's overall GF Score™ is 24/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For IN8bio (INAB), the current Return-on-Tangible-Equity is -80.89% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

IN8bio Business Description

Address 350 5th Avenue, Suite 5330, New York, NY, USA, 10118
IN8bio Inc is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of gamma-delta T cellular therapy product candidates and gamma-delta T cell engagers (TCEs) for cancer and autoimmune diseases. Gamma-delta T cells are a specialized population of T cells that possess properties. It has conducted two primary investigator-sponsored Phase 1 clinical trials evaluating its gamma-delta T cell technologies in cancer patients, which have both completed primary enrollment. INB-100 is assessing its DeltEx Allogeneic (Allo) gamma-delta T cell therapy in adult patients with high-risk leukemias undergoing haploidentical stem cell transplantation (HSCT). It operates in a single segment.
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