ISPC (iSpecimen) Return-on-Tangible-Equity: 0.00% (As of Mar. 2026)


ISPC iSpecimen Inc ISPC
49 GF Score
Price $2.63
GF Value $6.69
Valuation Possible Value Trap
! 7 Warning Signs
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What is iSpecimen Return-on-Tangible-Equity?

iSpecimen ISPC -3.30% 49 Return-on-Tangible-Equity is 0.00% as of Mar. 2026. GuruFocus rates ISPC with a GF Score™ of 49/100 and a GF Value™ of $6.69 (Possible Value Trap). The stock has 7 warning signs investors should review. Among 192 Medical Diagnostics & Research companies, iSpecimen ranks worse than 520832.81% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. iSpecimen's annualized net income for the quarter that ended in Mar. 2026 was $-9.10 Mil. iSpecimen's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $-0.60 Mil. Therefore, iSpecimen's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was N/A%.

The historical rank and industry rank for iSpecimen's Return-on-Tangible-Equity or its related term are showing as below:

ISPC's Return-on-Tangible-Equity is not ranked *
in the Medical Diagnostics & Research industry.
Industry Median: -0.405
* Ranked among companies with meaningful Return-on-Tangible-Equity only.

iSpecimen  (NAS:ISPC) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


iSpecimen Return-on-Tangible-Equity Related Terms


iSpecimen Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for iSpecimen's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

iSpecimen Return-on-Tangible-Equity Chart

iSpecimen Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial 0.00 -47.78 -121.20 -5,080.49 0.00

iSpecimen Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

ISPC vs BIAF, FUNI, IVRO: Return-on-Tangible-Equity Comparison

For the Diagnostics & Research subindustry, iSpecimen's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


iSpecimen Return-on-Tangible-Equity vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, iSpecimen's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where iSpecimen's Return-on-Tangible-Equity falls into.


ISPC
49GF Score
iSpecimen Inc ISPC
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

iSpecimen Return-on-Tangible-Equity Calculation

iSpecimen's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-10.488/( (-2.018+0.818 )/ 2 )
=-10.488/-0.6
=N/A %

iSpecimen's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-9.1/( (0.818+-2.022)/ 2 )
=-9.1/-0.602
=N/A %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of 0.00% mean?
iSpecimen (ISPC) has a Return-on-Tangible-Equity of 0.00% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on iSpecimen and its competitors. According to the industry distribution chart, iSpecimen ranks #999999 out of 192 companies in the Medical Diagnostics & Research industry.
Is iSpecimen's Return-on-Tangible-Equity too high?
iSpecimen's current Return-on-Tangible-Equity is 0.00%. Based on the distribution chart, iSpecimen ranks #999999 out of 192 companies in the Medical Diagnostics & Research industry, which is in the bottom quartile relative to peers. Overall, iSpecimen has a GF Score™ of 49/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does iSpecimen's Return-on-Tangible-Equity compare to BIAF and FUNI?
According to the Medical Diagnostics & Research industry distribution chart, iSpecimen ranks #999999 out of 192 companies for Return-on-Tangible-Equity. This places iSpecimen in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Medical Diagnostics & Research company?
A good Return-on-Tangible-Equity depends on the Medical Diagnostics & Research industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on iSpecimen and its competitors. iSpecimen's current Return-on-Tangible-Equity is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is iSpecimen stock overvalued right now?
Based on GuruFocus' analysis, iSpecimen (ISPC) is currently considered Possible Value Trap. The stock's GF Value™ is $6.69, compared to a current price of $2.63 — trading 60.7% below its estimated fair value. The current Return-on-Tangible-Equity is 0.00%. iSpecimen's overall GF Score™ is 49/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For iSpecimen (ISPC), the current Return-on-Tangible-Equity is 0.00% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is iSpecimen (ISPC) Overvalued in 2026?

Based on GuruFocus' analysis, iSpecimen stock appears to be undervalued. The current stock price of $2.63 is trading 60.7% below its estimated GF Value™ of $6.69. GuruFocus considers iSpecimen to be Possible Value Trap.

Key valuation signals for ISPC:

  • Return-on-Tangible-Equity: 0.00%
  • GF Value™: $6.69 vs. price of $2.63 (60.7% below fair value)
  • GF Score™: 49/100 with 7 warning signs

No single metric tells the full story. See the ISPC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


iSpecimen Business Description

Address 8 Cabot Road, Suite 1800, Woburn, MA, USA, 01801
iSpecimen Inc is a technology-driven company focused on connecting life science researchers who need human biofluids, solid tissues, and hematopoietic stem and immune cells for their research with the available biospecimens. The company generates revenue by procuring various specimens from hospitals, laboratories, and other supply sites. Geographically, it has a presence in the Americas, Europe, the Middle East, Africa, and the Asia Pacific, with the majority coming from the Americas. The Company has one reportable segment: biospecimens.
49GF Score

Get the complete analysis for ISPC

Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$2.63
Price
$6.69
GF Value