MBRX (Moleculin Biotech) Return-on-Tangible-Equity: -1,301.91% (As of Mar. 2026)


MBRX Moleculin Biotech Inc MBRX
30 GF Score
Price $2.64
! 1 Warning Sign
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What is Moleculin Biotech Return-on-Tangible-Equity?

Moleculin Biotech MBRX -1.86% 30 Return-on-Tangible-Equity is -1,301.91% as of Mar. 2026. GuruFocus rates MBRX with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 1,199 Biotechnology companies, Moleculin Biotech ranks worse than 83402.75% on this metric.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. Moleculin Biotech's annualized net income for the quarter that ended in Mar. 2026 was $-51.38 Mil. Moleculin Biotech's average shareholder tangible equity for the quarter that ended in Mar. 2026 was $3.95 Mil. Therefore, Moleculin Biotech's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 was -1,301.91%.

The historical rank and industry rank for Moleculin Biotech's Return-on-Tangible-Equity or its related term are showing as below:

MBRX's Return-on-Tangible-Equity is not ranked *
in the Biotechnology industry.
Industry Median: -42.4
* Ranked among companies with meaningful Return-on-Tangible-Equity only.

Moleculin Biotech  (NAS:MBRX) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


Moleculin Biotech Return-on-Tangible-Equity Related Terms


Moleculin Biotech Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for Moleculin Biotech's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Moleculin Biotech Return-on-Tangible-Equity Chart

Moleculin Biotech Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Return-on-Tangible-Equity
Get a 7-Day Free Trial Premium Member Only Premium Member Only -42.69 -53.31 -106.38 -347.65 -1,713.12

Moleculin Biotech Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 Negative Tangible Equity -1,301.91

MBRX vs JAGX, BCDA, AKTX: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, Moleculin Biotech's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Moleculin Biotech Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Moleculin Biotech's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where Moleculin Biotech's Return-on-Tangible-Equity falls into.


MBRX
30GF Score
Moleculin Biotech Inc MBRX
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
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Moleculin Biotech Return-on-Tangible-Equity Calculation

Moleculin Biotech's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-33.56/( (0.06+3.858 )/ 2 )
=-33.56/1.959
=-1,713.12 %

Moleculin Biotech's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2026 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2026 )  (Q: Dec. 2025 )(Q: Mar. 2026 )
=-51.38/( (3.858+4.035)/ 2 )
=-51.38/3.9465
=-1,301.91 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2026) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of -1,301.91% mean?
Moleculin Biotech (MBRX) has a Return-on-Tangible-Equity of -1,301.91% as of Mar. 2026. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Moleculin Biotech and its competitors. According to the industry distribution chart, Moleculin Biotech ranks #999999 out of 1199 companies in the Biotechnology industry.
Is Moleculin Biotech's Return-on-Tangible-Equity too high?
Moleculin Biotech's current Return-on-Tangible-Equity is -1,301.91%. Based on the distribution chart, Moleculin Biotech ranks #999999 out of 1199 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Moleculin Biotech has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Moleculin Biotech's Return-on-Tangible-Equity compare to JAGX and BCDA?
According to the Biotechnology industry distribution chart, Moleculin Biotech ranks #999999 out of 1199 companies for Return-on-Tangible-Equity. This places Moleculin Biotech in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on Moleculin Biotech and its competitors. Moleculin Biotech's current Return-on-Tangible-Equity is -1,301.91%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Moleculin Biotech stock overvalued right now?
Moleculin Biotech (MBRX) has a current Return-on-Tangible-Equity of -1,301.91%. The current Return-on-Tangible-Equity is -1,301.91%. Moleculin Biotech's overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For Moleculin Biotech (MBRX), the current Return-on-Tangible-Equity is -1,301.91% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Moleculin Biotech Business Description

Other Exchanges 0K2H:UK
Address 5300 Memorial Drive, Suite 950, Houston, TX, USA, 77007
Moleculin Biotech Inc is a late-stage pharmaceutical development company currently evaluating Annamycin, also known as L-Annamycin and by its generic name naxtarubicin. The company has two additional portfolios of technologies for hard-to-treat cancers and viruses with clinical and preclinical research funded by investigators at academic institutions. The Company operates in one reportable segment, which is the development and commercialization of drug products.
30GF Score

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