MBRX (Moleculin Biotech) 3-Year Sortino Ratio: 6.49 (As of Sep. 10, 2026)

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MBRX Moleculin Biotech Inc MBRX
29 GF Score
Price $0.77
! 1 Warning Sign
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What is Moleculin Biotech 3-Year Sortino Ratio?

Moleculin Biotech MBRX +0.53% 29 3-Year Sortino Ratio is 6.49 as of Sep. 10, 2026. GuruFocus rates MBRX with a GF Score™ of 29/100. The stock has 1 warning sign investors should review.

The 3-Year Sortino Ratio measures the additional return that an investor receives per unit of the downside risk over the past three years. As of today (2026-09-10), Moleculin Biotech's 3-Year Sortino Ratio is 6.49.


Moleculin Biotech  (NAS:MBRX) 3-Year Sortino Ratio Explanation

The 3-Year Sortino Ratio inidicates the risk-adjusted return of an investment over the past three year. It is calculated as the annualized result of the average three-year monthly excess returns divided by the standard deviation of negative returns in the three-year period. The monthly excess return is the monthly investment return minus the monthly risk-free rate (typically the 10-year Treasury Constant Maturity Rate). If the risk-free rate for a specific region is not available, U.S. data is used by default.

Differnt from the Sharpe Ratio that penalizes both upside and downside volatility equally, the Sortino Ratio penalizes only those returns falling below a user-specified target or required rate of return. The expected returns here is set to the risk-free rate as well.


Moleculin Biotech 3-Year Sortino Ratio Related Terms


MBRX vs BCLI, ANEB, ASBP: 3-Year Sortino Ratio Comparison

For the Biotechnology subindustry, Moleculin Biotech's 3-Year Sortino Ratio, along with its competitors' market caps and 3-Year Sortino Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Moleculin Biotech 3-Year Sortino Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Moleculin Biotech's 3-Year Sortino Ratio distribution charts can be found below:

* The bar in red indicates where Moleculin Biotech's 3-Year Sortino Ratio falls into.


MBRX
29GF Score
Moleculin Biotech Inc MBRX
3-Year Sortino Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
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Moleculin Biotech 3-Year Sortino Ratio Calculation

The 3-Year Sortino Ratio measures the risk-adjusted return of an investment asset or portfolio in the last three year, focusing specifically on downside risk rather than total risk. A stock / portfolio's 3-Year Sortino Ratio can be calculated by dividing the difference between the three-year average monthly returns of the investment and the risk-free rate, by the standard deviation of the downside risks over the past three year.

A downside risk is a potential loss from the asset or investment. The Downside risk here is measured by the downside deviation, which is the standard deviation of negative returns.

Frequently Asked Questions Learn more about 3-Year Sortino Ratio →
What does a 3-Year Sortino Ratio of 6.49 mean?
Moleculin Biotech (MBRX) has a 3-Year Sortino Ratio of 6.49 as of Sep. 10, 2026. 3-Year Sortino Ratio measures the additional return that an investor receives per unit of the downside risk over the past three years. View historical data for Moleculin Biotech and its competitors.
Is Moleculin Biotech's 3-Year Sortino Ratio too high?
Moleculin Biotech's current 3-Year Sortino Ratio is 6.49. Overall, Moleculin Biotech has a GF Score™ of 29/100, reflecting its overall financial health beyond just this single metric.
How does Moleculin Biotech's 3-Year Sortino Ratio compare to BCLI and ANEB?
Moleculin Biotech's 3-Year Sortino Ratio of 6.49 can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good 3-Year Sortino Ratio for a Biotechnology company?
A good 3-Year Sortino Ratio depends on the Biotechnology industry context. However, 3-Year Sortino Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high 3-Year Sortino Ratio mean?
A high 3-Year Sortino Ratio can signal that a stock is expensive relative to its fundamentals. 3-Year Sortino Ratio measures the additional return that an investor receives per unit of the downside risk over the past three years. View historical data for Moleculin Biotech and its competitors. Moleculin Biotech's current 3-Year Sortino Ratio is 6.49. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Moleculin Biotech stock overvalued right now?
Moleculin Biotech (MBRX) has a current 3-Year Sortino Ratio of 6.49. The current 3-Year Sortino Ratio is 6.49. Moleculin Biotech's overall GF Score™ is 29/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is 3-Year Sortino Ratio calculated?
3-Year Sortino Ratio is calculated from a company's financial statements. For Moleculin Biotech (MBRX), the current 3-Year Sortino Ratio is 6.49 as of Sep. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Moleculin Biotech Business Description

Other Exchanges 0K2H:UK
Address 5300 Memorial Drive, Suite 950, Houston, TX, USA, 77007
Moleculin Biotech Inc is a late-stage pharmaceutical development company currently evaluating Annamycin, also known as L-Annamycin and by its generic name naxtarubicin. The company has two additional portfolios of technologies for hard-to-treat cancers and viruses with clinical and preclinical research funded by investigators at academic institutions. The Company operates in one reportable segment, which is the development and commercialization of drug products.
29GF Score

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3-Year Sortino Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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