2seventy bio (MEX:TSVT) Return-on-Tangible-Equity: 0.92% (As of Mar. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MEX:TSVT 2seventy bio Inc MEX:TSVT
9 GF Score
Price MXN170.00
View Full Analysis

What is 2seventy bio Return-on-Tangible-Equity?

2seventy bio MEX:TSVT 9 Return-on-Tangible-Equity is 0.92% as of Mar. 2025. GuruFocus rates MEX:TSVT with a GF Score™ of 9/100.

Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. 2seventy bio's annualized net income for the quarter that ended in Mar. 2025 was MXN39.4 Mil. 2seventy bio's average shareholder tangible equity for the quarter that ended in Mar. 2025 was MXN4,267.1 Mil. Therefore, 2seventy bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2025 was 0.92%.

The historical rank and industry rank for 2seventy bio's Return-on-Tangible-Equity or its related term are showing as below:

MEX:TSVT's Return-on-Tangible-Equity is not ranked *
in the Biotechnology industry.
Industry Median: -41.98
* Ranked among companies with meaningful Return-on-Tangible-Equity only.

2seventy bio  (MEX:TSVT) Return-on-Tangible-Equity Explanation

Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.


Be Aware

Net Income is used.

Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.

Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.


2seventy bio Return-on-Tangible-Equity Related Terms


2seventy bio Return-on-Tangible-Equity Historical Data

* Premium members only.

The historical data trend for 2seventy bio's Return-on-Tangible-Equity can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2seventy bio Return-on-Tangible-Equity Chart

2seventy bio Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Return-on-Tangible-Equity
Get a 7-Day Free Trial -316.43 -149.07 -78.61 -74.63 -28.11

2seventy bio Quarterly Data
Dec19 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25
Return-on-Tangible-Equity Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -92.53 48.47 -18.28 -37.67 0.92

MEX:TSVT vs ALMS, TERN, CRVS: Return-on-Tangible-Equity Comparison

For the Biotechnology subindustry, 2seventy bio's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


2seventy bio Return-on-Tangible-Equity vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, 2seventy bio's Return-on-Tangible-Equity distribution charts can be found below:

* The bar in red indicates where 2seventy bio's Return-on-Tangible-Equity falls into.


MEX:TSVT
9GF Score
2seventy bio Inc MEX:TSVT
Return-on-Tangible-Equity is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

2seventy bio Return-on-Tangible-Equity Calculation

2seventy bio's annualized Return-on-Tangible-Equity for the fiscal year that ended in Dec. 2024 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(A: Dec. 2024 )  (A: Dec. 2023 )(A: Dec. 2024 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets )/ count )
(A: Dec. 2024 )  (A: Dec. 2023 )(A: Dec. 2024 )
=-1193.926/( (4221.598+4273.771 )/ 2 )
=-1193.926/4247.6845
=-28.11 %

2seventy bio's annualized Return-on-Tangible-Equity for the quarter that ended in Mar. 2025 is calculated as

Return-on-Tangible-Equity=Net Income/( (Total Tangible Equity+Total Tangible Equity)/ count )
(Q: Mar. 2025 )  (Q: Dec. 2024 )(Q: Mar. 2025 )
=Net Income/( (Total Stockholders Equity - Intangible Assets+Total Stockholders Equity - Intangible Assets)/ count )
(Q: Mar. 2025 )  (Q: Dec. 2024 )(Q: Mar. 2025 )
=39.444/( (4273.771+4260.482)/ 2 )
=39.444/4267.1265
=0.92 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data, the net income data used here is four times the quarterly (Mar. 2025) net income data. Return-on-Tangible-Equity is displayed in the 10-year financial page.

What does a Return-on-Tangible-Equity of 0.92% mean?
2seventy bio (MEX:TSVT) has a Return-on-Tangible-Equity of 0.92% as of Mar. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on 2seventy bio and its competitors.
Is 2seventy bio's Return-on-Tangible-Equity too high?
2seventy bio's current Return-on-Tangible-Equity is 0.92%. Overall, 2seventy bio has a GF Score™ of 9/100, reflecting its overall financial health beyond just this single metric.
How does 2seventy bio's Return-on-Tangible-Equity compare to ALMS and TERN?
2seventy bio's Return-on-Tangible-Equity of 0.92% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on 2seventy bio and its competitors. 2seventy bio's current Return-on-Tangible-Equity is 0.92%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is 2seventy bio stock overvalued right now?
2seventy bio (MEX:TSVT) has a current Return-on-Tangible-Equity of 0.92%. The current Return-on-Tangible-Equity is 0.92%. 2seventy bio's overall GF Score™ is 9/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For 2seventy bio (MEX:TSVT), the current Return-on-Tangible-Equity is 0.92% as of Mar. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

2seventy bio Business Description

Address 60 Binney Street, Cambridge, MA, USA, 02142
2seventy bio Inc is a cell and gene therapy company focused on the research, development, and commercialization of transformative treatments for cancer. The company operates in a single segment focusing on researching, developing and commercializing potentially transformative treatments for cancer.
9GF Score

Get the complete analysis for MEX:TSVT

Return-on-Tangible-Equity is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

MXN170.00
Price