2seventy bio (MEX:TSVT) Piotroski F-Score: 0 (As of Aug. 25, 2026)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
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Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

MEX:TSVT 2seventy bio Inc MEX:TSVT
9 GF Score
Price MXN170.00
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What is 2seventy bio Piotroski F-Score?

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

2seventy bio has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for 2seventy bio's Piotroski F-Score or its related term are showing as below:

2seventy bio  (MEX:TSVT) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


2seventy bio Piotroski F-Score Related Terms


2seventy bio Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for 2seventy bio's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

2seventy bio Piotroski F-Score Chart

2seventy bio Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24
Piotroski F-Score
Get a 7-Day Free Trial N/A N/A 5.00 5.00 2.00

2seventy bio Quarterly Data
Dec19 Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.00 2.00 2.00 2.00 3.00
MEX:TSVT
9GF Score
2seventy bio Inc MEX:TSVT
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Mar25) TTM:Last Year (Mar24) TTM:
Net Income was 455.786 + -195.584 + -407.103 + 9.861 = MXN-137.0 Mil.
Cash Flow from Operations was -423.964 + -206.847 + -197.587 + -224.488 = MXN-1,052.9 Mil.
Revenue was 164.276 + 266.489 + 61.024 + 469.27 = MXN961.1 Mil.
Gross Profit was 101.017 + 152.915 + -123.403 + 363.849 = MXN494.4 Mil.
Average Total Assets from the begining of this year (Mar24)
to the end of this year (Mar25) was
(8481.533 + 9487.908 + 9920.879 + 10000.517 + 9820.038) / 5 = MXN9542.175 Mil.
Total Assets at the begining of this year (Mar24) was MXN8,481.5 Mil.
Long-Term Debt & Capital Lease Obligation was MXN4,562.2 Mil.
Total Current Assets was MXN4,062.6 Mil.
Total Current Liabilities was MXN846.9 Mil.
Net Income was -721.57 + -1247.855 + -964.511 + -874.175 = MXN-3,808.1 Mil.

Revenue was 618.003 + 209.619 + 181.353 + 206.374 = MXN1,215.3 Mil.
Gross Profit was 540.564 + 123.239 + 127.935 + 131.708 = MXN923.4 Mil.
Average Total Assets from the begining of last year (Mar23)
to the end of last year (Mar24) was
(13382.427 + 12098.673 + 11162.134 + 9597.681 + 8481.533) / 5 = MXN10944.4896 Mil.
Total Assets at the begining of last year (Mar23) was MXN13,382.4 Mil.
Long-Term Debt & Capital Lease Obligation was MXN3,984.3 Mil.
Total Current Assets was MXN3,532.4 Mil.
Total Current Liabilities was MXN1,002.5 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

2seventy bio's current Net Income (TTM) was -137.0. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

2seventy bio's current Cash Flow from Operations (TTM) was -1,052.9. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Mar24)
=-137.04/8481.533
=-0.01615746

ROA (Last Year)=Net Income/Total Assets (Mar23)
=-3808.111/13382.427
=-0.28456057

2seventy bio's return on assets of this year was -0.01615746. 2seventy bio's return on assets of last year was -0.28456057. ==> This year is higher. ==> Score 1.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

2seventy bio's current Net Income (TTM) was -137.0. 2seventy bio's current Cash Flow from Operations (TTM) was -1,052.9. ==> -1,052.9 <= -137.0 ==> CFROA <= ROA ==> Score 0.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Mar25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar24 to Mar25
=4562.22/9542.175
=0.47811112

Gearing (Last Year: Mar24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar23 to Mar24
=3984.28/10944.4896
=0.36404439

2seventy bio's gearing of this year was 0.47811112. 2seventy bio's gearing of last year was 0.36404439. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Mar25)=Total Current Assets/Total Current Liabilities
=4062.63/846.908
=4.79701455

Current Ratio (Last Year: Mar24)=Total Current Assets/Total Current Liabilities
=3532.38/1002.513
=3.52352538

2seventy bio's current ratio of this year was 4.79701455. 2seventy bio's current ratio of last year was 3.52352538. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

2seventy bio's number of shares in issue this year was 53.433. 2seventy bio's number of shares in issue last year was 52.071. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=494.378/961.059
=0.51440963

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=923.446/1215.349
=0.75981961

2seventy bio's gross margin of this year was 0.51440963. 2seventy bio's gross margin of last year was 0.75981961. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Mar24)
=961.059/8481.533
=0.11331194

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Mar23)
=1215.349/13382.427
=0.09081679

2seventy bio's asset turnover of this year was 0.11331194. 2seventy bio's asset turnover of last year was 0.09081679. ==> This year's asset turnover is higher. ==> Score 1.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+1+0+0+1+0+0+1
=3

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

2seventy bio has an F-score of 3. It is a bad or low score, which usually implies poor business operation.


2seventy bio Business Description

Address 60 Binney Street, Cambridge, MA, USA, 02142
2seventy bio Inc is a cell and gene therapy company focused on the research, development, and commercialization of transformative treatments for cancer. The company operates in a single segment focusing on researching, developing and commercializing potentially transformative treatments for cancer.
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MXN170.00
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