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TME Pharma NVXPAR:ALTME +1.65% Return-on-Tangible-Equity is 0.00% as of Dec. 2025. The stock has 4 warning signs investors should review. Among 1,199 Biotechnology companies, TME Pharma NV ranks worse than 99.92% on this metric.
Return-on-Tangible-Equity is calculated as Net Income divided by its average total shareholder tangible equity. Total shareholder tangible equity equals to Total Stockholders Equity minus Intangible Assets. TME Pharma NV's annualized net income for the quarter that ended in Dec. 2025 was €-2.37 Mil. TME Pharma NV's average shareholder tangible equity for the quarter that ended in Dec. 2025 was €-1.08 Mil. Therefore, TME Pharma NV's annualized Return-on-Tangible-Equity for the quarter that ended in Dec. 2025 was N/A%.
The historical rank and industry rank for TME Pharma NV's Return-on-Tangible-Equity or its related term are showing as below:
XPAR:ALTME'
s Return-on-Tangible-Equity Range Over the Past 10 Years
Min: -24333.33 Med: -872.26 Max: -236.59
Current: -24333.33
During the past 12 years, TME Pharma NV's highest Return-on-Tangible-Equity was -236.59%. The lowest was -24,333.33%. And the median was -872.26%.
XPAR:ALTME's Return-on-Tangible-Equity is ranked worse than 99.92% of 1199
companies
in the Biotechnology industry
Industry Median: -42.21
vs XPAR:ALTME: -24333.33
Return-on-Tangible-Equity measures the rate of return on the ownership interest (shareholder's tangible equity) of the common stock owners. It measures a firm's efficiency at generating profits from every unit of shareholders' tangible equity (shareholders equity minus intangibles). Return-on-Tangible-Equity shows how well a company uses investment funds to generate earnings growth. Return-on-Tangible-Equitys between 15% and 20% are considered desirable.
Be Aware
Net Income is used.
Because a company can increase its Return-on-Tangible-Equity by having more financial leverage, it is important to watch the leverage ratio when investing in high Return-on-Tangible-Equity companies. Like Return-on-Tangible-Asset, Return-on-Tangible-Equity is calculated with only 12 months data. Fluctuations in company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.
Asset light businesses require very few assets to generate very high earnings. Their Return-on-Tangible-Equitys can be extremely high.
TME Pharma NV Return-on-Tangible-Equity Related Terms
TME Pharma NV Return-on-Tangible-Equity Historical Data
* Premium members only.
The historical data trend for TME Pharma NV's Return-on-Tangible-Equity can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
XPAR:ALTME vs VRTX, REGN, ALNY: Return-on-Tangible-Equity Comparison
For the Biotechnology subindustry, TME Pharma NV's Return-on-Tangible-Equity, along with its competitors' market caps and Return-on-Tangible-Equity data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
TME Pharma NV Return-on-Tangible-Equity vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, TME Pharma NV's Return-on-Tangible-Equity distribution charts can be found below:
* The bar in red indicates where TME Pharma NV's Return-on-Tangible-Equity falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual Return-on-Tangible-Equity, the net income of the last fiscal year and the average total shareholder tangible equity over the fiscal year are used. In calculating the quarterly data,
the net income data used here is two times the semi-annual (Dec. 2025) net income data.
Return-on-Tangible-Equity is displayed in the 10-year financial page.
What does a Return-on-Tangible-Equity of 0.00% mean?
TME Pharma NV (XPAR:ALTME) has a Return-on-Tangible-Equity of 0.00% as of Dec. 2025. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on TME Pharma NV and its competitors. According to the industry distribution chart, TME Pharma NV ranks #1198 out of 1199 companies in the Biotechnology industry, placing it in the top 99.9%.
Is TME Pharma NV's Return-on-Tangible-Equity too high?
TME Pharma NV's current Return-on-Tangible-Equity is 0.00%. Based on the distribution chart, TME Pharma NV ranks #1198 out of 1199 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does TME Pharma NV's Return-on-Tangible-Equity compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, TME Pharma NV ranks #1198 out of 1199 companies for Return-on-Tangible-Equity. This places TME Pharma NV in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Return-on-Tangible-Equity for a Biotechnology company?
A good Return-on-Tangible-Equity depends on the Biotechnology industry context. However, Return-on-Tangible-Equity should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Return-on-Tangible-Equity mean?
A high Return-on-Tangible-Equity can signal that a stock is expensive relative to its fundamentals. Return on tangible equity is the ratio of current-period net income to average two-period tangible equity. View historical data on TME Pharma NV and its competitors. TME Pharma NV's current Return-on-Tangible-Equity is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is TME Pharma NV stock overvalued right now?
TME Pharma NV (XPAR:ALTME) has a current Return-on-Tangible-Equity of 0.00%. The current Return-on-Tangible-Equity is 0.00%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Return-on-Tangible-Equity calculated?
Return-on-Tangible-Equity is calculated from a company's financial statements. For TME Pharma NV (XPAR:ALTME), the current Return-on-Tangible-Equity is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
TME Pharma NV is a clinical-stage biopharmaceutical company focused on developing novel therapies for treatment of the aggressive cancers and specializing in approaches targeting the tumor microenvironment. Its enhances the effectiveness of cancer treatments including current standards of care (such as antivascular agents, chemotherapy and radiotherapy) and immune-oncology approaches (such as immune checkpoint inhibitors). The company's Spiegelmer platform has generated a proprietary pipeline of clinical-stage product candidates including its cancer drug candidate NOX-A12 and its second clinical-stage asset, NOX-E36, now planned to be developed in eye diseases. The company has one segment active in pioneering the development of a new class of proprietary therapeutics called Spiegelmers.
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