CRDF (Cardiff Oncology) ROA %: -88.93% (As of Mar. 2026)


CRDF Cardiff Oncology Inc CRDF
53 GF Score
Price $1.21
GF Value $1.49
Valuation Modestly Undervalued
! 4 Warning Signs
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What is Cardiff Oncology ROA %?

Cardiff Oncology CRDF -3.97% 53 ROA % is -88.93% as of Mar. 2026. GuruFocus rates CRDF with a GF Score™ of 53/100 and a GF Value™ of $1.49 (Modestly Undervalued). The stock has 4 warning signs investors should review. Among 1,423 Biotechnology companies, Cardiff Oncology ranks worse than 72.45% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Cardiff Oncology's annualized Net Income for the quarter that ended in Mar. 2026 was $-49.38 Mil. Cardiff Oncology's average Total Assets over the quarter that ended in Mar. 2026 was $55.53 Mil. Therefore, Cardiff Oncology's annualized ROA % for the quarter that ended in Mar. 2026 was -88.93%.

The historical rank and industry rank for Cardiff Oncology's ROA % or its related term are showing as below:

CRDF' s ROA % Range Over the Past 10 Years
Min: -124.44   Med: -54.23   Max: -19.9
Current: -66.73

During the past 13 years, Cardiff Oncology's highest ROA % was -19.90%. The lowest was -124.44%. And the median was -54.23%.

CRDF's ROA % is ranked worse than
72.45% of 1423 companies
in the Biotechnology industry
Industry Median: -32.9 vs CRDF: -66.73

Cardiff Oncology  (NAS:CRDF) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-49.38/55.528
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-49.38 / 0.164)*(0.164 / 55.528)
=Net Margin %*Asset Turnover
=-30109.76 %*0.003
=-88.93 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


Cardiff Oncology ROA % Related Terms


Cardiff Oncology ROA % Historical Data

* Premium members only.

The historical data trend for Cardiff Oncology's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cardiff Oncology ROA % Chart

Cardiff Oncology Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -19.90 -29.13 -41.90 -50.81 -57.65

Cardiff Oncology Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -59.05 -69.48 -64.55 -45.94 -88.93

CRDF vs VTVT, GUTS, BDTX: ROA % Comparison

For the Biotechnology subindustry, Cardiff Oncology's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cardiff Oncology ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cardiff Oncology's ROA % distribution charts can be found below:

* The bar in red indicates where Cardiff Oncology's ROA % falls into.


CRDF
53GF Score
Cardiff Oncology Inc CRDF
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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Cardiff Oncology ROA % Calculation

Cardiff Oncology's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-45.851/( (97.19+61.884)/ 2 )
=-45.851/79.537
=-57.65 %

Cardiff Oncology's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-49.38/( (61.884+49.172)/ 2 )
=-49.38/55.528
=-88.93 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -88.93% mean?
Cardiff Oncology (CRDF) has a ROA % of -88.93% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Cardiff Oncology and its competitors. According to the industry distribution chart, Cardiff Oncology ranks #1031 out of 1423 companies in the Biotechnology industry, placing it in the top 72.5%.
Is Cardiff Oncology's ROA % too high?
Cardiff Oncology's current ROA % is -88.93%. Based on the distribution chart, Cardiff Oncology ranks #1031 out of 1423 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Cardiff Oncology has a GF Score™ of 53/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Cardiff Oncology's ROA % compare to VTVT and GUTS?
According to the Biotechnology industry distribution chart, Cardiff Oncology ranks #1031 out of 1423 companies for ROA %. This places Cardiff Oncology in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Cardiff Oncology and its competitors. Cardiff Oncology's current ROA % is -88.93%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cardiff Oncology stock overvalued right now?
Based on GuruFocus' analysis, Cardiff Oncology (CRDF) is currently considered Modestly Undervalued. The stock's GF Value™ is $1.49, compared to a current price of $1.21 — trading 18.8% below its estimated fair value. The current ROA % is -88.93%. Cardiff Oncology's overall GF Score™ is 53/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Cardiff Oncology (CRDF), the current ROA % is -88.93% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cardiff Oncology (CRDF) Overvalued in 2026?

Based on GuruFocus' analysis, Cardiff Oncology stock appears to be undervalued. The current stock price of $1.21 is trading 18.8% below its estimated GF Value™ of $1.49. GuruFocus considers Cardiff Oncology to be Modestly Undervalued.

Key valuation signals for CRDF:

  • ROA %: -88.93%
  • GF Value™: $1.49 vs. price of $1.21 (18.8% below fair value)
  • GF Score™: 53/100 with 4 warning signs

No single metric tells the full story. See the CRDF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cardiff Oncology Business Description

Other Exchanges XE7C:Germany
Address 11055 Flintkote Avenue, San Diego, CA, USA, 92121
Cardiff Oncology Inc is a clinical-stage biotechnology company that leverages PLK1 inhibition, a well-validated oncology drug target, to develop novel therapies for various cancers with unmet medical needs. The company focuses on targeting tumor vulnerabilities with treatment combinations of onvansertib, its oral and selective PLK1 inhibitor, and standard-of-care (SoC) therapeutics. The firm's clinical program pipeline focuses on indications such as RAS-mutated metastatic colorectal cancer (mCRC), investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma (mPDAC), small cell lung cancer (SCLC), metastatic triple negative breast cancer (mTNBC), and Chronic Myelomonocytic Leukemia (CMML). Geographically, it operates only in the United States.
53GF Score

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$1.21
Price
$1.49
GF Value