CRDF (Cardiff Oncology) ROE % Adjusted to Book Value: -38.65% (As of Mar. 2026)


CRDF Cardiff Oncology Inc CRDF
53 GF Score
Price $1.25
GF Value $1.48
Valuation Modestly Undervalued
! 4 Warning Signs
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What is Cardiff Oncology ROE % Adjusted to Book Value?

Cardiff Oncology CRDF +3.31% 53 ROE % Adjusted to Book Value is -38.65% as of Mar. 2026. GuruFocus rates CRDF with a GF Score™ of 53/100 and a GF Value™ of $1.48 (Modestly Undervalued). The stock has 4 warning signs investors should review.

Cardiff Oncology's ROE % for the quarter that ended in Mar. 2026 was -123.30%. Cardiff Oncology's PB Ratio for the quarter that ended in Mar. 2026 was 3.19. Cardiff Oncology's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -38.65%.


Cardiff Oncology ROE % Adjusted to Book Value Related Terms


Cardiff Oncology ROE % Adjusted to Book Value Historical Data

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The historical data trend for Cardiff Oncology's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cardiff Oncology ROE % Adjusted to Book Value Chart

Cardiff Oncology Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -11.71 -53.17 -49.55 -17.10 -16.89

Cardiff Oncology Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -23.68 -24.06 -29.63 -14.49 -38.65

CRDF vs VTVT, GUTS, BDTX: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Cardiff Oncology's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cardiff Oncology ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cardiff Oncology's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Cardiff Oncology's ROE % Adjusted to Book Value falls into.


CRDF
53GF Score
Cardiff Oncology Inc CRDF
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Cardiff Oncology ROE % Adjusted to Book Value Calculation

Cardiff Oncology's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-71.45% / 4.23
=-16.89%

Cardiff Oncology's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-123.30% / 3.19
=-38.65%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -38.65% mean?
Cardiff Oncology (CRDF) has a ROE % Adjusted to Book Value of -38.65% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Cardiff Oncology and its competitors.
Is Cardiff Oncology's ROE % Adjusted to Book Value too high?
Cardiff Oncology's current ROE % Adjusted to Book Value is -38.65%. Overall, Cardiff Oncology has a GF Score™ of 53/100 and is considered Modestly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Cardiff Oncology's ROE % Adjusted to Book Value compare to VTVT and GUTS?
Cardiff Oncology's ROE % Adjusted to Book Value of -38.65% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Cardiff Oncology and its competitors. Cardiff Oncology's current ROE % Adjusted to Book Value is -38.65%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cardiff Oncology stock overvalued right now?
Based on GuruFocus' analysis, Cardiff Oncology (CRDF) is currently considered Modestly Undervalued. The stock's GF Value™ is $1.48, compared to a current price of $1.25 — trading 15.5% below its estimated fair value. The current ROE % Adjusted to Book Value is -38.65%. Cardiff Oncology's overall GF Score™ is 53/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Cardiff Oncology (CRDF), the current ROE % Adjusted to Book Value is -38.65% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Cardiff Oncology (CRDF) Overvalued in 2026?

Based on GuruFocus' analysis, Cardiff Oncology stock appears to be undervalued. The current stock price of $1.25 is trading 15.5% below its estimated GF Value™ of $1.48. GuruFocus considers Cardiff Oncology to be Modestly Undervalued.

Key valuation signals for CRDF:

  • ROE % Adjusted to Book Value: -38.65%
  • GF Value™: $1.48 vs. price of $1.25 (15.5% below fair value)
  • GF Score™: 53/100 with 4 warning signs

No single metric tells the full story. See the CRDF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Cardiff Oncology Business Description

Other Exchanges XE7C:Germany
Address 11055 Flintkote Avenue, San Diego, CA, USA, 92121
Cardiff Oncology Inc is a clinical-stage biotechnology company that leverages PLK1 inhibition, a well-validated oncology drug target, to develop novel therapies for various cancers with unmet medical needs. The company focuses on targeting tumor vulnerabilities with treatment combinations of onvansertib, its oral and selective PLK1 inhibitor, and standard-of-care (SoC) therapeutics. The firm's clinical program pipeline focuses on indications such as RAS-mutated metastatic colorectal cancer (mCRC), investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma (mPDAC), small cell lung cancer (SCLC), metastatic triple negative breast cancer (mTNBC), and Chronic Myelomonocytic Leukemia (CMML). Geographically, it operates only in the United States.
53GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.25
Price
$1.48
GF Value