ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. Bicycle Therapeutics's annualizedNet Income for the quarter that ended in Mar. 2026 was €-210.46 Mil.
Bicycle Therapeutics's average Total Assets over the quarter that ended in Mar. 2026 was €588.58 Mil. Therefore, Bicycle Therapeutics's annualized ROA % for the quarter that ended in Mar. 2026 was -35.76%.
The historical rank and industry rank for Bicycle Therapeutics's ROA % or its related term are showing as below:
STU:50BA'
s ROA % Range Over the Past 10 Years
Min: -37.6 Med: -26.15 Max: -20.85
Current: -28.45
During the past 9 years, Bicycle Therapeutics's highest ROA % was -20.85%. The lowest was -37.60%. And the median was -26.15%.
STU:50BA's ROA % is ranked better than 52.64% of 1423
companies
in the Biotechnology industry
Industry Median: -33.07
vs STU:50BA: -28.45
Bicycle Therapeutics (STU:50BA) ROA % Explanation
ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A banks ROA % is typically well under 2%.
Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:
Note:
The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Be Aware
Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).
Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.
E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Bicycle Therapeutics's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Bicycle Therapeutics ROA % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Bicycle Therapeutics's ROA % distribution charts can be found below:
* The bar in red indicates where Bicycle Therapeutics's ROA % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data,
the Net Income data used here is four times the quarterly (Mar. 2026) net income data.
ROA % is displayed in the 30-year financial page.
Bicycle Therapeutics (STU:50BA) has a ROA % of -35.76% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Bicycle Therapeutics and its competitors. According to the industry distribution chart, Bicycle Therapeutics ranks #674 out of 1423 companies in the Biotechnology industry, placing it in the top 47.4%.
Is Bicycle Therapeutics' ROA % too high?
Bicycle Therapeutics' current ROA % is -35.76%. Based on the distribution chart, Bicycle Therapeutics ranks #674 out of 1423 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Bicycle Therapeutics has a GF Score™ of 54/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Bicycle Therapeutics' ROA % compare to ABEO and DMAC?
According to the Biotechnology industry distribution chart, Bicycle Therapeutics ranks #674 out of 1423 companies for ROA %. This puts Bicycle Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on Bicycle Therapeutics and its competitors. Bicycle Therapeutics's current ROA % is -35.76%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bicycle Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Bicycle Therapeutics (STU:50BA) is currently considered Possible Value Trap. The stock's GF Value™ is €13.23, compared to a current price of €3.48 — trading 73.7% below its estimated fair value. The current ROA % is -35.76%. Bicycle Therapeutics' overall GF Score™ is 54/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For Bicycle Therapeutics (STU:50BA), the current ROA % is -35.76% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Bicycle Therapeutics (STU:50BA) Overvalued in 2026?
Based on GuruFocus' analysis, Bicycle Therapeutics stock appears to be undervalued.
The current stock price of €3.48 is trading 73.7% below its estimated GF Value™ of €13.23.
GuruFocus considers Bicycle Therapeutics to be Possible Value Trap.
Key valuation signals for STU:50BA:
ROA %: -35.76%
GF Value™: €13.23 vs. price of €3.48 (73.7% below fair value)
No single metric tells the full story. See the STU:50BA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops that stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical needs. The company's product candidate, BT1718, is a Bicycle Toxin Conjugate, or BTC. The company has two segments: the United Kingdom and the United States. It derives maximum revenue from United Kingdom.
54GF Score
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