Bicycle Therapeutics (STU:50BA) ROIC %: -457.44% (As of Mar. 2026)


STU:50BA Bicycle Therapeutics PLC STU:50BA
54 GF Score
Price €3.48
GF Value €13.23
Valuation Possible Value Trap
! 5 Warning Signs
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What is Bicycle Therapeutics ROIC %?

Bicycle Therapeutics STU:50BA +1.16% 54 ROIC % is -457.44% as of Mar. 2026. GuruFocus rates STU:50BA with a GF Score™ of 54/100 and a GF Value™ of €13.23 (Possible Value Trap). The stock has 5 warning signs investors should review.

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. Bicycle Therapeutics's annualized return on invested capital (ROIC %) for the quarter that ended in Mar. 2026 was -457.44%.

As of today (2026-06-24), Bicycle Therapeutics's WACC % is 14.18%. Bicycle Therapeutics's ROIC % is -383.89% (calculated using TTM income statement data). Bicycle Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Bicycle Therapeutics  (STU:50BA) ROIC % Explanation

ROIC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROIC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Bicycle Therapeutics's WACC % is 14.18%. Bicycle Therapeutics's ROIC % is -383.89% (calculated using TTM income statement data). Bicycle Therapeutics earns returns that do not match up to its cost of capital. It will destroy value as it grows.


Be Aware

Like ROE % and ROA %, ROIC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Bicycle Therapeutics ROIC % Related Terms


Bicycle Therapeutics ROIC % Historical Data

* Premium members only.

The historical data trend for Bicycle Therapeutics's ROIC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Bicycle Therapeutics ROIC % Chart

Bicycle Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROIC %
Get a 7-Day Free Trial Premium Member Only -184.50 -187.24 -244.47 -302.61 -395.56

Bicycle Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROIC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -456.32 -549.12 -363.74 -145.22 -457.44

STU:50BA vs ABEO, DMAC, FATE: ROIC % Comparison

For the Biotechnology subindustry, Bicycle Therapeutics's ROIC %, along with its competitors' market caps and ROIC % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Bicycle Therapeutics ROIC % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Bicycle Therapeutics's ROIC % distribution charts can be found below:

* The bar in red indicates where Bicycle Therapeutics's ROIC % falls into.


STU:50BA
54GF Score
Bicycle Therapeutics PLC STU:50BA
ROIC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Bicycle Therapeutics ROIC % Calculation

Bicycle Therapeutics's annualized Return on Invested Capital (ROIC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROIC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=-211.551 * ( 1 - 0% )/( (57.803 + 49.16)/ 2 )
=-211.551/53.4815
=-395.56 %

where

Invested Capital(A: Dec. 2024 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=913.809 - 33.393 - ( 839.942 - max(0, 64.205 - 886.818+839.942))
=57.803

Bicycle Therapeutics's annualized Return on Invested Capital (ROIC %) for the quarter that ended in Mar. 2026 is calculated as:

ROIC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=-226.936 * ( 1 - 0% )/( (49.16 + 50.06)/ 2 )
=-226.936/49.61
=-457.44 %

where

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROIC % →
What does a ROIC % of -457.44% mean?
Bicycle Therapeutics (STU:50BA) has a ROIC % of -457.44% as of Mar. 2026. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Bicycle Therapeutics and its competitors.
Is Bicycle Therapeutics' ROIC % too high?
Bicycle Therapeutics' current ROIC % is -457.44%. Overall, Bicycle Therapeutics has a GF Score™ of 54/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Bicycle Therapeutics' ROIC % compare to ABEO and DMAC?
Bicycle Therapeutics' ROIC % of -457.44% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROIC % for a Biotechnology company?
A good ROIC % depends on the Biotechnology industry context. However, ROIC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROIC % mean?
A high ROIC % can signal that a stock is expensive relative to its fundamentals. Return on invested capital is the ratio of current-period net income to average two-period invested capital. View historical data on Bicycle Therapeutics and its competitors. Bicycle Therapeutics's current ROIC % is -457.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bicycle Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Bicycle Therapeutics (STU:50BA) is currently considered Possible Value Trap. The stock's GF Value™ is €13.23, compared to a current price of €3.48 — trading 73.7% below its estimated fair value. The current ROIC % is -457.44%. Bicycle Therapeutics' overall GF Score™ is 54/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROIC % calculated?
ROIC % is calculated from a company's financial statements. For Bicycle Therapeutics (STU:50BA), the current ROIC % is -457.44% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Bicycle Therapeutics (STU:50BA) Overvalued in 2026?

Based on GuruFocus' analysis, Bicycle Therapeutics stock appears to be undervalued. The current stock price of €3.48 is trading 73.7% below its estimated GF Value™ of €13.23. GuruFocus considers Bicycle Therapeutics to be Possible Value Trap.

Key valuation signals for STU:50BA:

  • ROIC %: -457.44%
  • GF Value™: €13.23 vs. price of €3.48 (73.7% below fair value)
  • GF Score™: 54/100 with 5 warning signs

No single metric tells the full story. See the STU:50BA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Bicycle Therapeutics Business Description

Other Exchanges BCYC:USA
Address Granta Park, Great Abington, Blocks A and B, Portway Building, Cambridge, GBR, CB21 6GS
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops that stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical needs. The company's product candidate, BT1718, is a Bicycle Toxin Conjugate, or BTC. The company has two segments: the United Kingdom and the United States. It derives maximum revenue from United Kingdom.
54GF Score

Get the complete analysis for STU:50BA

ROIC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€3.48
Price
€13.23
GF Value