ZVSA (ZyVersa Therapeutics) ROA %: -1,315.96% (As of Mar. 2026)


ZVSA ZyVersa Therapeutics Inc ZVSA
30 GF Score
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What is ZyVersa Therapeutics ROA %?

ZyVersa Therapeutics ZVSA -9.60% 30 ROA % is -1,315.96% as of Mar. 2026. GuruFocus rates ZVSA with a GF Score™ of 30/100. The stock has 1 warning sign investors should review. Among 1,423 Biotechnology companies, ZyVersa Therapeutics ranks worse than 95.92% on this metric.

ROA % is calculated as Net Income divided by its average Total Assets over a certain period of time. ZyVersa Therapeutics's annualized Net Income for the quarter that ended in Mar. 2026 was $-7.17 Mil. ZyVersa Therapeutics's average Total Assets over the quarter that ended in Mar. 2026 was $0.55 Mil. Therefore, ZyVersa Therapeutics's annualized ROA % for the quarter that ended in Mar. 2026 was -1,315.96%.

The historical rank and industry rank for ZyVersa Therapeutics's ROA % or its related term are showing as below:

ZVSA' s ROA % Range Over the Past 10 Years
Min: -1848.83   Med: -189.03   Max: -23.49
Current: -286.37

During the past 6 years, ZyVersa Therapeutics's highest ROA % was -23.49%. The lowest was -1848.83%. And the median was -189.03%.

ZVSA's ROA % is ranked worse than
95.92% of 1423 companies
in the Biotechnology industry
Industry Median: -32.9 vs ZVSA: -286.37

ZyVersa Therapeutics  (OTCPK:ZVSA) ROA % Explanation

ROA % measures the rate of return on the total assets (shareholder equity plus liabilities). It measures a firm's efficiency at generating profits from shareholders' equity plus its liabilities. ROA % shows how well a company uses what it has to generate earnings. ROA %s can vary drastically across industries. Therefore, ROA % should not be used to compare companies in different industries. For retailers, a ROA % of higher than 5% is expected. For example, Wal-Mart (WMT) has a ROA % of about 8% as of 2012. For banks, ROA % is close to their interest spread. A bank’s ROA % is typically well under 2%.

Similar to ROE, ROA % is affected by profit margins and asset turnover. This can be seen from the Du Pont Formula:

ROA %(Q: Mar. 2026 )
=Net Income/Total Assets
=-7.172/0.545
=(Net Income / Revenue)*(Revenue / Total Assets)
=(-7.172 / 0)*(0 / 0.545)
=Net Margin %*Asset Turnover
=N/A %*0
=-1,315.96 %

Note: The Net Income data used here is four times the quarterly (Mar. 2026) net income data. The Revenue data used here is four times the quarterly (Mar. 2026) revenue data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.


Be Aware

Like ROE, ROA % is calculated with only 12 months data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective. ROA % can be affected by events such as stock buyback or issuance, and by goodwill, a company's tax rate and its interest payment. ROA % may not reflect the true earning power of the assets. A more accurate measurement is ROC % (ROC).

Many analysts argue the higher return the better. Buffett states that really high ROA % may indicate vulnerability in the durability of the competitive advantage.

E.g. Raising $43b to take on KO is impossible, but $1.7b to take on Moody's is. Although Moody's ROA % and underlying economics is far superior to Coca Cola, the durability is far weaker because of lower entry cost.


ZyVersa Therapeutics ROA % Related Terms


ZyVersa Therapeutics ROA % Historical Data

* Premium members only.

The historical data trend for ZyVersa Therapeutics's ROA % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ZyVersa Therapeutics ROA % Chart

ZyVersa Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROA %
Get a 7-Day Free Trial -892.27 -23.49 -139.81 -44.08 -238.24

ZyVersa Therapeutics Quarterly Data
Dec20 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROA % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -43.42 -43.54 -766.15 -391.35 -1,315.96

ZVSA vs CLSDQ, ADAPY, BPTH: ROA % Comparison

For the Biotechnology subindustry, ZyVersa Therapeutics's ROA %, along with its competitors' market caps and ROA % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ZyVersa Therapeutics ROA % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ZyVersa Therapeutics's ROA % distribution charts can be found below:

* The bar in red indicates where ZyVersa Therapeutics's ROA % falls into.


ZVSA
30GF Score
ZyVersa Therapeutics Inc ZVSA
ROA % is just one metric. See GF Score™, valuation, warning signs, and more.
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ZyVersa Therapeutics ROA % Calculation

ZyVersa Therapeutics's annualized ROA % for the fiscal year that ended in Dec. 2025 is calculated as:

ROA %=Net Income (A: Dec. 2025 )/( (Total Assets (A: Dec. 2024 )+Total Assets (A: Dec. 2025 ))/ count )
=-24.952/( (20.599+0.348)/ 2 )
=-24.952/10.4735
=-238.24 %

ZyVersa Therapeutics's annualized ROA % for the quarter that ended in Mar. 2026 is calculated as:

ROA %=Net Income (Q: Mar. 2026 )/( (Total Assets (Q: Dec. 2025 )+Total Assets (Q: Mar. 2026 ))/ count )
=-7.172/( (0.348+0.742)/ 2 )
=-7.172/0.545
=-1,315.96 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

In the calculation of annual ROA %, the net income of the last fiscal year and the average total assets over the fiscal year are used. In calculating the quarterly data, the Net Income data used here is four times the quarterly (Mar. 2026) net income data. ROA % is displayed in the 30-year financial page.

Frequently Asked Questions Learn more about ROA % →
What does a ROA % of -1,315.96% mean?
ZyVersa Therapeutics (ZVSA) has a ROA % of -1,315.96% as of Mar. 2026. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on ZyVersa Therapeutics and its competitors. According to the industry distribution chart, ZyVersa Therapeutics ranks #1365 out of 1423 companies in the Biotechnology industry, placing it in the top 95.9%.
Is ZyVersa Therapeutics' ROA % too high?
ZyVersa Therapeutics' current ROA % is -1,315.96%. Based on the distribution chart, ZyVersa Therapeutics ranks #1365 out of 1423 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, ZyVersa Therapeutics has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does ZyVersa Therapeutics' ROA % compare to CLSDQ and ADAPY?
According to the Biotechnology industry distribution chart, ZyVersa Therapeutics ranks #1365 out of 1423 companies for ROA %. This places ZyVersa Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROA % for a Biotechnology company?
A good ROA % depends on the Biotechnology industry context. However, ROA % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROA % mean?
A high ROA % can signal that a stock is expensive relative to its fundamentals. Return on assets is the ratio of current-period net income to average two-period total assets. View historical data on ZyVersa Therapeutics and its competitors. ZyVersa Therapeutics's current ROA % is -1,315.96%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ZyVersa Therapeutics stock overvalued right now?
ZyVersa Therapeutics (ZVSA) has a current ROA % of -1,315.96%. The current ROA % is -1,315.96%. ZyVersa Therapeutics' overall GF Score™ is 30/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROA % calculated?
ROA % is calculated from a company's financial statements. For ZyVersa Therapeutics (ZVSA), the current ROA % is -1,315.96% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ZyVersa Therapeutics Business Description

Address 2200 North Commerce Parkway, Suite 208, Weston, FL, USA, 33326
ZyVersa Therapeutics Inc is a clinical-stage biopharmaceutical company leveraging proprietary technologies to develop drugs for patients with chronic renal or inflammatory diseases with high unmet medical needs. The company has two proprietary globally licensed drug development platforms which are Cholesterol Efflux MediatorTM, VAR 200 (2-hydroxypropyl-beta-cyclodextrin) is an injectable drug in clinical development for the treatment of renal diseases. and IC 100 is a monoclonal antibody inflammasome ASC inhibitor in preclinical development for the treatment of inflammatory conditions.
30GF Score

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