Illumina (XTER:ILU) ROC %: 15.29% (As of Mar. 2026)


XTER:ILU Illumina Inc XTER:ILU
76 GF Score
Price €124.28
GF Value €90.37
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Illumina ROC %?

Illumina XTER:ILU +0.60% 76 ROC % is 15.29% as of Mar. 2026. GuruFocus rates XTER:ILU with a GF Score™ of 76/100 and a GF Value™ of €90.37 (Significantly Overvalued). The stock has 7 warning signs investors should review.

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. Illumina's annualized return on capital (ROC %) for the quarter that ended in Mar. 2026 was 15.29%.

As of today (2026-06-26), Illumina's WACC % is 11.95%. Illumina's ROC % is 14.83% (calculated using TTM income statement data). Illumina generates higher returns on investment than it costs the company to raise the capital needed for that investment. It is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases.


Illumina  (XTER:ILU) ROC % Explanation

ROC % measures how well a company generates cash flow relative to the capital it has invested in its business. It is also called ROIC %. The reason book values of debt and equity are used is because the book values are the capital the company received when issuing the debt or receiving the equity investments.

There are four key components to this definition. The first is the use of operating income or EBIT rather than net income in the numerator. The second is the tax adjustment to this operating income or EBIT, computed as a hypothetical tax based on an effective or marginal tax rate. The third is the use of book values for invested capital, rather than market values. The final is the timing difference; the capital invested is from the end of the prior year whereas the operating income or EBIT is the current year's number.

Why is ROC % important?

Because it costs money to raise capital. A firm that generates higher returns on investment than it costs the company to raise the capital needed for that investment is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases, whereas a firm that earns returns that do not match up to its cost of capital will destroy value as it grows.

As of today, Illumina's WACC % is 11.95%. Illumina's ROC % is 14.83% (calculated using TTM income statement data). Illumina generates higher returns on investment than it costs the company to raise the capital needed for that investment. It is earning excess returns. A firm that expects to continue generating positive excess returns on new investments in the future will see its value increase as growth increases.


Be Aware

Like ROE % and ROA %, ROC % is calculated with only 12 months of data. Fluctuations in the company's earnings or business cycles can affect the ratio drastically. It is important to look at the ratio from a long term perspective.


Illumina ROC % Related Terms


Illumina ROC % Historical Data

* Premium members only.

The historical data trend for Illumina's ROC % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Illumina ROC % Chart

Illumina Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROC %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -1.24 3.09 -2.36 9.69 13.16

Illumina Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROC % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 10.11 14.06 13.02 15.85 15.29
XTER:ILU
76GF Score
Illumina Inc XTER:ILU
ROC % is just one metric. See GF Score™, valuation, warning signs, and more.
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Illumina ROC % Calculation

Illumina's annualized Return on Capital (ROC %) for the fiscal year that ended in Dec. 2025 is calculated as:

ROC % (A: Dec. 2025 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (A: Dec. 2024 ) + Invested Capital (A: Dec. 2025 ))/ count )
=697.718 * ( 1 - 21.73% )/( (4437.885 + 3861.788)/ 2 )
=546.1038786/4149.8365
=13.16 %

where

Invested Capital(A: Dec. 2024 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=6019.365 - 436.435 - ( 1165.1 - max(0, 1477.385 - 2622.43+1165.1))
=4437.885

Invested Capital(A: Dec. 2025 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=5673.976 - 417.606 - ( 1394.582 - max(0, 1353.59 - 2808.806+1394.582))
=3861.788

Illumina's annualized Return on Capital (ROC %) for the quarter that ended in Mar. 2026 is calculated as:

ROC % (Q: Mar. 2026 )
=NOPAT/Average Invested Capital
=Operating Income * ( 1 - Tax Rate % )/( (Invested Capital (Q: Dec. 2025 ) + Invested Capital (Q: Mar. 2026 ))/ count )
=723.14 * ( 1 - 14.65% )/( (3861.788 + 4210.82)/ 2 )
=617.19999/4036.304
=15.29 %

where

Invested Capital(Q: Dec. 2025 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=5673.976 - 417.606 - ( 1394.582 - max(0, 1353.59 - 2808.806+1394.582))
=3861.788

Invested Capital(Q: Mar. 2026 )
=Total Assets - Accounts Payable & Accrued Expense - Excess Cash
=Total Assets - Accounts Payable & Accrued Expense - ( Cash, Cash Equivalents, Marketable Securities - max(0, Total Current Liabilities - Total Current Assets+Cash, Cash Equivalents, Marketable Securities))
=5673.535 - 463.64 - ( 999.075 - max(0, 1354.59 - 2368.37+999.075))
=4210.82

Note: The Operating Income data used here is four times the quarterly (Mar. 2026) data. The tax rate is limited to between 0% and 100%.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROC % →
What does a ROC % of 15.29% mean?
Illumina (XTER:ILU) has a ROC % of 15.29% as of Mar. 2026. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Illumina and its competitors.
Is Illumina's ROC % too high?
Illumina's current ROC % is 15.29%. Overall, Illumina has a GF Score™ of 76/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Illumina's ROC % compare to MTD and DGX?
Illumina's ROC % of 15.29% can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROC % for a Medical Diagnostics & Research company?
A good ROC % depends on the Medical Diagnostics & Research industry context. However, ROC % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROC % mean?
A high ROC % can signal that a stock is expensive relative to its fundamentals. Return on capital is the ratio of current-period net income to average two-period capital. View historical data on Illumina and its competitors. Illumina's current ROC % is 15.29%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Illumina stock overvalued right now?
Based on GuruFocus' analysis, Illumina (XTER:ILU) is currently considered Significantly Overvalued. The stock's GF Value™ is €90.37, compared to a current price of €124.28 — trading 37.5% above its estimated fair value. The current ROC % is 15.29%. Illumina's overall GF Score™ is 76/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROC % calculated?
ROC % is calculated from a company's financial statements. For Illumina (XTER:ILU), the current ROC % is 15.29% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Illumina (XTER:ILU) Overvalued in 2026?

Based on GuruFocus' analysis, Illumina stock appears to be overvalued. The current stock price of €124.28 is trading 37.5% above its estimated GF Value™ of €90.37. GuruFocus considers Illumina to be Significantly Overvalued.

Key valuation signals for XTER:ILU:

  • ROC %: 15.29%
  • GF Value™: €90.37 vs. price of €124.28 (37.5% above fair value)
  • GF Score™: 76/100 with 7 warning signs

No single metric tells the full story. See the XTER:ILU stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Illumina Business Description

Address 5200 Illumina Way, San Diego, CA, USA, 92122
Illumina provides tools and services to analyze genetic material with life science and clinical lab applications. The company generates over 90% of its revenue from sequencing instruments, consumables, and services. Illumina's high-throughput technology enables whole genome sequencing in humans and other large organisms. Its lower throughput tools enable applications that require smaller data outputs, such as viral and cancer tumor screening. Illumina also sells microarrays (9% of 2024 sales) that enable lower-cost, focused genetic screening with primarily consumer and agricultural applications.
76GF Score

Get the complete analysis for XTER:ILU

ROC % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€124.28
Price
€90.37
GF Value