Oxford Nanopore Technologies (LSE:ONT) ROCE %: -25.98% (As of Dec. 2025)


LSE:ONT Oxford Nanopore Technologies PLC LSE:ONT
74 GF Score
Price £1.24
GF Value £1.87
Valuation Significantly Undervalued
! 2 Warning Signs
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What is Oxford Nanopore Technologies ROCE %?

Oxford Nanopore Technologies LSE:ONT +2.31% 74 ROCE % is -25.98% as of Dec. 2025. GuruFocus rates LSE:ONT with a GF Score™ of 74/100 and a GF Value™ of £1.87 (Significantly Undervalued). The stock has 2 warning signs investors should review.

ROCE % measures how well a company generates profits from its capital. It is calculated as EBIT divided by Capital Employed, where Capital Employed is calculated as Total Assets minus Total Current Liabilities. Oxford Nanopore Technologies's annualized ROCE % for the quarter that ended in Dec. 2025 was -25.98%.

Oxford Nanopore Technologies  (LSE:ONT) ROCE % Explanation

ROCE % can be especially useful when comparing the performance of capital-intensive companies. Unlike ROE %, which indicates the profitability of Shareholders Equity, ROCE % also considers long-term debt in Capital Employed. This can be helpful when analyzing companies with significant debt, as the result is neutralized by taking debt into consideration.

Generally speaking, a higher ROCE % indicates a stonger profitability for a company. Moreover, it is important to look at the ratio from a long term perspective. Investors tend to favor companies with stable and rising ROCE % trend over those with volatile ones.

Oxford Nanopore Technologies ROCE % Related Terms

Oxford Nanopore Technologies ROCE % Historical Data

* Premium members only.

The historical data trend for Oxford Nanopore Technologies's ROCE % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oxford Nanopore Technologies ROCE % Chart

Oxford Nanopore Technologies Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROCE %
Get a 7-Day Free Trial -34.91 -11.13 -20.78 -20.69 -24.16

Oxford Nanopore Technologies Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROCE % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -24.21 -21.17 -21.37 -22.60 -25.98
LSE:ONT
74GF Score
Oxford Nanopore Technologies PLC LSE:ONT
ROCE % is just one metric. See GF Score™, valuation, warning signs, and more.
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Oxford Nanopore Technologies ROCE % Calculation

Oxford Nanopore Technologies's annualized ROCE % for the fiscal year that ended in Dec. 2025 is calculated as:

ROCE %=EBIT/( (Capital Employed+Capital Employed)/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=EBIT/( ( (Total Assets - Total Current Liabilities)+(Total Assets - Total Current Liabilities) )/ count )
(A: Dec. 2025 )  (A: Dec. 2024 )(A: Dec. 2025 )
=-137.1/( ( (742 - 111.5) + (622.5 - 118) )/ 2 )
=-137.1/( (630.5+504.5)/ 2 )
=-137.1/567.5
=-24.16 %

Oxford Nanopore Technologies's ROCE % of for the quarter that ended in Dec. 2025 is calculated as:

ROCE %=EBIT (1)/( (Capital Employed+Capital Employed)/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=EBIT/( ( (Total Assets - Total Current Liabilities)+(Total Assets - Total Current Liabilities) )/ count )
(Q: Dec. 2025 )  (Q: Jun. 2025 )(Q: Dec. 2025 )
=-139/( ( (671.7 - 106) + (622.5 - 118) )/ 2 )
=-139/( ( 565.7 + 504.5 )/ 2 )
=-139/535.1
=-25.98 %

(1) Note: The EBIT data used here is two times the semi-annual (Dec. 2025) EBIT data.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about ROCE % →
What does a ROCE % of -25.98% mean?
Oxford Nanopore Technologies (LSE:ONT) has a ROCE % of -25.98% as of Dec. 2025.
Is Oxford Nanopore Technologies' ROCE % too high?
Oxford Nanopore Technologies' current ROCE % is -25.98%. Overall, Oxford Nanopore Technologies has a GF Score™ of 74/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Oxford Nanopore Technologies' ROCE % compare to VRTX and REGN?
Oxford Nanopore Technologies' ROCE % of -25.98% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROCE % for a Biotechnology company?
A good ROCE % depends on the Biotechnology industry context. However, ROCE % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROCE % mean?
A high ROCE % can signal that a stock is expensive relative to its fundamentals. Oxford Nanopore Technologies's current ROCE % is -25.98%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford Nanopore Technologies stock overvalued right now?
Based on GuruFocus' analysis, Oxford Nanopore Technologies (LSE:ONT) is currently considered Significantly Undervalued. The stock's GF Value™ is £1.87, compared to a current price of £1.24 — trading 33.6% below its estimated fair value. The current ROCE % is -25.98%. Oxford Nanopore Technologies' overall GF Score™ is 74/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROCE % calculated?
ROCE % is calculated from a company's financial statements. For Oxford Nanopore Technologies (LSE:ONT), the current ROCE % is -25.98% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oxford Nanopore Technologies (LSE:ONT) Overvalued in 2026?

Based on GuruFocus' analysis, Oxford Nanopore Technologies stock appears to be undervalued. The current stock price of £1.24 is trading 33.6% below its estimated GF Value™ of £1.87. GuruFocus considers Oxford Nanopore Technologies to be Significantly Undervalued.

Key valuation signals for LSE:ONT:

  • ROCE %: -25.98%
  • GF Value™: £1.87 vs. price of £1.24 (33.6% below fair value)
  • GF Score™: 74/100 with 2 warning signs

No single metric tells the full story. See the LSE:ONT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Oxford Nanopore Technologies Business Description

Address Edmund Halley Road, Gosling Building, Oxford Science Park, Oxford, Oxfordshire, GBR, OX4 4DQ
Oxford Nanopore Technologies PLC is involved in researching, developing, manufacturing and commercializing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing technology that provides rich data, is fast, accessible and easy to use, and which allows the real-time analysis of DNA or RNA. It has developed and brought to market a new generation molecular sensing platform based on nanopores. The first application is DNA/RNA sequencing and the platform is also being developed for the analysis of proteins and metabolites. It operates in single segment of providing products and services related to the sale and use of its nanopore-based sensing technology. Geographically its operations are spread across EMES, AMR, and APAC.
74GF Score

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ROCE % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£1.24
Price
£1.87
GF Value