Oxford Nanopore Technologies (LSE:ONT) Net Margin %: -62.05% (As of Dec. 2025)


LSE:ONT Oxford Nanopore Technologies PLC LSE:ONT
74 GF Score
Price £1.15
GF Value £1.87
Valuation Significantly Undervalued
! 2 Warning Signs
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What is Oxford Nanopore Technologies Net Margin %?

Oxford Nanopore Technologies LSE:ONT +1.33% 74 Net Margin % is -62.05% as of Dec. 2025. GuruFocus rates LSE:ONT with a GF Score™ of 74/100 and a GF Value™ of £1.87 (Significantly Undervalued). The stock has 2 warning signs investors should review. Among 947 Biotechnology companies, Oxford Nanopore Technologies ranks better than 52.8% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Oxford Nanopore Technologies's Net Income for the six months ended in Dec. 2025 was £-73.4 Mil. Oxford Nanopore Technologies's Revenue for the six months ended in Dec. 2025 was £118.3 Mil. Therefore, Oxford Nanopore Technologies's net margin for the quarter that ended in Dec. 2025 was -62.05%.

The historical rank and industry rank for Oxford Nanopore Technologies's Net Margin % or its related term are showing as below:

LSE:ONT' s Net Margin % Range Over the Past 10 Years
Min: -163.34   Med: -85.43   Max: -45.83
Current: -64.85


LSE:ONT's Net Margin % is ranked better than
52.8% of 947 companies
in the Biotechnology industry
Industry Median: -89.56 vs LSE:ONT: -64.85

Oxford Nanopore Technologies  (LSE:ONT) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Oxford Nanopore Technologies Net Margin % Related Terms


Oxford Nanopore Technologies Net Margin % Historical Data

* Premium members only.

The historical data trend for Oxford Nanopore Technologies's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Oxford Nanopore Technologies Net Margin % Chart

Oxford Nanopore Technologies Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial -125.40 -45.83 -91.06 -79.80 -64.85

Oxford Nanopore Technologies Semi-Annual Data
Dec18 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -100.89 -88.82 -72.15 -67.99 -62.05

LSE:ONT vs VRTX, REGN, ALNY: Net Margin % Comparison

For the Biotechnology subindustry, Oxford Nanopore Technologies's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Oxford Nanopore Technologies Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Oxford Nanopore Technologies's Net Margin % distribution charts can be found below:

* The bar in red indicates where Oxford Nanopore Technologies's Net Margin % falls into.


LSE:ONT
74GF Score
Oxford Nanopore Technologies PLC LSE:ONT
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Oxford Nanopore Technologies Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Oxford Nanopore Technologies's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-145.2/223.9
=-64.85 %

Oxford Nanopore Technologies's Net Margin for the quarter that ended in Dec. 2025 is calculated as

Net Margin=Net Income (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-73.4/118.3
=-62.05 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -62.05% mean?
Oxford Nanopore Technologies (LSE:ONT) has a Net Margin % of -62.05% as of Dec. 2025. Net margin is the ratio of total net income to net sales. View historical data on Oxford Nanopore Technologies and its competitors. According to the industry distribution chart, Oxford Nanopore Technologies ranks #447 out of 947 companies in the Biotechnology industry, placing it in the top 47.2%.
Is Oxford Nanopore Technologies' Net Margin % too high?
Oxford Nanopore Technologies' current Net Margin % is -62.05%. Based on the distribution chart, Oxford Nanopore Technologies ranks #447 out of 947 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Oxford Nanopore Technologies has a GF Score™ of 74/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Oxford Nanopore Technologies' Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Oxford Nanopore Technologies ranks #447 out of 947 companies for Net Margin %. This puts Oxford Nanopore Technologies in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Oxford Nanopore Technologies and its competitors. Oxford Nanopore Technologies's current Net Margin % is -62.05%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oxford Nanopore Technologies stock overvalued right now?
Based on GuruFocus' analysis, Oxford Nanopore Technologies (LSE:ONT) is currently considered Significantly Undervalued. The stock's GF Value™ is £1.87, compared to a current price of £1.15 — trading 38.7% below its estimated fair value. The current Net Margin % is -62.05%. Oxford Nanopore Technologies' overall GF Score™ is 74/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Oxford Nanopore Technologies (LSE:ONT), the current Net Margin % is -62.05% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Oxford Nanopore Technologies (LSE:ONT) Overvalued in 2026?

Based on GuruFocus' analysis, Oxford Nanopore Technologies stock appears to be undervalued. The current stock price of £1.15 is trading 38.7% below its estimated GF Value™ of £1.87. GuruFocus considers Oxford Nanopore Technologies to be Significantly Undervalued.

Key valuation signals for LSE:ONT:

  • Net Margin %: -62.05%
  • GF Value™: £1.87 vs. price of £1.15 (38.7% below fair value)
  • GF Score™: 74/100 with 2 warning signs

No single metric tells the full story. See the LSE:ONT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Oxford Nanopore Technologies Business Description

Address Edmund Halley Road, Gosling Building, Oxford Science Park, Oxford, Oxfordshire, GBR, OX4 4DQ
Oxford Nanopore Technologies PLC is involved in researching, developing, manufacturing and commercializing deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) sequencing technology that provides rich data, is fast, accessible and easy to use, and which allows the real-time analysis of DNA or RNA. It has developed and brought to market a new generation molecular sensing platform based on nanopores. The first application is DNA/RNA sequencing and the platform is also being developed for the analysis of proteins and metabolites. It operates in single segment of providing products and services related to the sale and use of its nanopore-based sensing technology. Geographically its operations are spread across EMES, AMR, and APAC.
74GF Score

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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

£1.15
Price
£1.87
GF Value