COTXF (Coiled Therapeutics) ROE % Adjusted to Book Value: -146.98% (As of Dec. 2025)


COTXF Coiled Therapeutics PLC COTXF
21 GF Score
Price $0.15
! 4 Warning Signs
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What is Coiled Therapeutics ROE % Adjusted to Book Value?

Coiled Therapeutics COTXF 21 ROE % Adjusted to Book Value is -146.98% as of Dec. 2025. GuruFocus rates COTXF with a GF Score™ of 21/100. The stock has 4 warning signs investors should review.

Coiled Therapeutics's ROE % for the quarter that ended in Dec. 2025 was -158.74%. Coiled Therapeutics's PB Ratio for the quarter that ended in Dec. 2025 was 1.08. Coiled Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 was -146.98%.

Coiled Therapeutics ROE % Adjusted to Book Value Related Terms

Coiled Therapeutics ROE % Adjusted to Book Value Historical Data

* Premium members only.

The historical data trend for Coiled Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Coiled Therapeutics ROE % Adjusted to Book Value Chart

Coiled Therapeutics Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
0.00 0.00 -12.59 -17.00 -88.47

Coiled Therapeutics Semi-Annual Data
Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only -14.44 -18.11 -14.48 -17.26 -146.98

COTXF vs VRTX, REGN, ALNY: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Coiled Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Coiled Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Coiled Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Coiled Therapeutics's ROE % Adjusted to Book Value falls into.


COTXF
21GF Score
Coiled Therapeutics PLC COTXF
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Coiled Therapeutics ROE % Adjusted to Book Value Calculation

Coiled Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-95.55% / 1.08
=-88.47%

Coiled Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-158.74% / 1.08
=-146.98%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -146.98% mean?
Coiled Therapeutics (COTXF) has a ROE % Adjusted to Book Value of -146.98% as of Dec. 2025. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Coiled Therapeutics and its competitors.
Is Coiled Therapeutics' ROE % Adjusted to Book Value too high?
Coiled Therapeutics' current ROE % Adjusted to Book Value is -146.98%. Overall, Coiled Therapeutics has a GF Score™ of 21/100, reflecting its overall financial health beyond just this single metric.
How does Coiled Therapeutics' ROE % Adjusted to Book Value compare to VRTX and REGN?
Coiled Therapeutics' ROE % Adjusted to Book Value of -146.98% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Coiled Therapeutics and its competitors. Coiled Therapeutics's current ROE % Adjusted to Book Value is -146.98%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Coiled Therapeutics stock overvalued right now?
Coiled Therapeutics (COTXF) has a current ROE % Adjusted to Book Value of -146.98%. The current ROE % Adjusted to Book Value is -146.98%. Coiled Therapeutics' overall GF Score™ is 21/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Coiled Therapeutics (COTXF), the current ROE % Adjusted to Book Value is -146.98% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Coiled Therapeutics Business Description

Other Exchanges COIL:UK0AG0:Germany
Address 85 Great Portland Street, First Floor, London, GBR, W1W 7LT
Coiled Therapeutics PLC principal activity of the Company is to develop pre-clinical next generation medicines focused on hard-to-treat cancers. The Group operated in the single business segment of biotechnology.
21GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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