ERNA (Ernexa Therapeutics) ROE % Adjusted to Book Value: -559.62% (As of Mar. 2026)


ERNA Ernexa Therapeutics Inc ERNA
30 GF Score
Price $6.60
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What is Ernexa Therapeutics ROE % Adjusted to Book Value?

Ernexa Therapeutics ERNA +0.61% 30 ROE % Adjusted to Book Value is -559.62% as of Mar. 2026. GuruFocus rates ERNA with a GF Score™ of 30/100. The stock has 4 warning signs investors should review.

Ernexa Therapeutics's ROE % for the quarter that ended in Mar. 2026 was -475.68%. Ernexa Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 0.85. Ernexa Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -559.62%.

Ernexa Therapeutics ROE % Adjusted to Book Value Related Terms

Ernexa Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Ernexa Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ernexa Therapeutics ROE % Adjusted to Book Value Chart

Ernexa Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial -86.14 -93.36 -71.61 -254.99 -174.73

Ernexa Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 -51.36 -51.21 -559.62

ERNA vs PMCB, SYBX, ASBP: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Ernexa Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Ernexa Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ernexa Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Ernexa Therapeutics's ROE % Adjusted to Book Value falls into.


ERNA
30GF Score
Ernexa Therapeutics Inc ERNA
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Ernexa Therapeutics ROE % Adjusted to Book Value Calculation

Ernexa Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-686.69% / 3.93
=-174.73%

Ernexa Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-475.68% / 0.85
=-559.62%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -559.62% mean?
Ernexa Therapeutics (ERNA) has a ROE % Adjusted to Book Value of -559.62% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Ernexa Therapeutics and its competitors.
Is Ernexa Therapeutics' ROE % Adjusted to Book Value too high?
Ernexa Therapeutics' current ROE % Adjusted to Book Value is -559.62%. Overall, Ernexa Therapeutics has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Ernexa Therapeutics' ROE % Adjusted to Book Value compare to PMCB and SYBX?
Ernexa Therapeutics' ROE % Adjusted to Book Value of -559.62% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Ernexa Therapeutics and its competitors. Ernexa Therapeutics's current ROE % Adjusted to Book Value is -559.62%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ernexa Therapeutics stock overvalued right now?
Ernexa Therapeutics (ERNA) has a current ROE % Adjusted to Book Value of -559.62%. The current ROE % Adjusted to Book Value is -559.62%. Ernexa Therapeutics' overall GF Score™ is 30/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Ernexa Therapeutics (ERNA), the current ROE % Adjusted to Book Value is -559.62% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Ernexa Therapeutics Business Description

Address 1035 Cambridge Street, Suite 18A, Cambridge, MA, USA, 02141
Ernexa Therapeutics Inc is a preclinical-stage synthetic allogeneic iMSC therapy company developing medicines to treat various forms of cancer and other diseases with high unmet medical needs. Its main product candidate, ERNA-101, capitalizes on the intrinsic tumor-homing ability of MSCs (mesenchymal stem cells) to slip through the tumor's defenses and to deliver potent pro-inflammatory factors directly to the tumor microenvironment. The firm's initial focus is to develop ERNA-101 in platinum-resistant ovarian cancer. Through another product candidate, ERNA-201, it is investigating anti-inflammatory cytokine (IL-10) secreting iMSCs in autoimmune disorders like rheumatoid arthritis. The company operates in a single reportable segment, the research and development of cellular therapies.
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